TLG Catalog - Stable
  • Stable
    • Dev
  1. Listings
  2. Pharmacokinetic
  3. PKPL01
  • Introduction

  • Tables
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      • LBT11_BL
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      • LBT12_BL
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      • LBT15
    • Medical History
      • MHT01
    • Pharmacokinetic
      • PKCT01
      • PKPT02
      • PKPT03
      • PKPT04
      • PKPT05
      • PKPT06
      • PKPT07
      • PKPT08
      • PKPT11
    • Risk Management Plan
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      • VST01
      • VST02
  • Listings
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      • ADAL02
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    • Development Safety Update Report
      • DSUR4
    • Disposition
      • DSL01
      • DSL02
    • ECG
      • EGL01
    • Efficacy
      • ONCL01
    • Exposure
      • EXL01
    • Lab Results
      • LBL01
      • LBL01_RLS
      • LBL02A
      • LBL02A_RLS
      • LBL02B
    • Medical History
      • MHL01
    • Pharmacokinetic
      • ADAL01
      • PKCL01
      • PKCL02
      • PKPL01
      • PKPL02
      • PKPL04
    • Vital Signs
      • VSL01
  • Graphs
    • Efficacy
      • FSTG01
      • FSTG02
      • KMG01
      • MMRMG01
      • MMRMG02
    • Other
      • BRG01
      • BWG01
      • CIG01
      • IPPG01
      • LTG01
      • MNG01
    • Pharmacokinetic
      • PKCG01
      • PKCG02
      • PKCG03
      • PKPG01
      • PKPG02
      • PKPG03
      • PKPG04
      • PKPG06

  • Appendix
    • Reproducibility

  • Index

On this page

  • Output
  • Reproducibility
    • Timestamp
    • Session Info
    • .lock file
  • Edit this page
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  1. Listings
  2. Pharmacokinetic
  3. PKPL01

PKPL01

Listing of Drug A Plasma PK Parameters


Output

  • Standard Listing
  • Data Setup
  • Preview
  • Try this using WebR
Code
lsting <- as_listing(
  out,
  key_cols = c("TRT01A", "USUBJID", "AVISIT"),
  disp_cols = names(out),
  main_title = paste("Listing of", drug_a, spec, "PK Parameters, PK Population\nProtocol: xxnnnnn"),
  subtitles = paste("Analyte:", drug_a)
)

head(lsting, 20)
Listing of Plasma Drug X Plasma PK Parameters, PK Population
Protocol: xxnnnnn
Analyte: Plasma Drug X

————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
Treatment Group        Subject ID             Visit       AUC Infinity Obs (day*ug/mL)   Max Conc (ug/mL)   Total CL Obs (ml/day/kg)
————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
   A: Drug X      AB12345-BRA-1-id-105      SCREENING           145.191684898102         35.5067335878638       5.1567601025515     
                                          CYCLE 1 DAY 1         246.349321001289         31.2264481880236       4.41386730113941    
                                          CYCLE 1 DAY 2         225.443483077171         43.4987268488453       4.81490455551286    
                  AB12345-BRA-1-id-134      SCREENING           157.461703380688         32.1171292884992       6.0374125711965     
                                          CYCLE 1 DAY 1         248.519038520728         21.7795763901966        4.561839813278     
                                          CYCLE 1 DAY 2         230.794839837734         21.0627132276049       6.95200595313275    
                   AB12345-BRA-1-id-42      SCREENING           194.224015921831         20.4565798423567       6.33709739029277    
                                          CYCLE 1 DAY 1         210.528307366678         26.7845825535397       3.50776680376268    
                                          CYCLE 1 DAY 2         167.592869235882         34.8276545020143       4.11969088323673    
                   AB12345-BRA-1-id-93      SCREENING           186.75868084484          27.3983170052516       3.40495133575408    
                                          CYCLE 1 DAY 1         160.406798051843         17.5296885232566       3.8508725098954     
                                          CYCLE 1 DAY 2         252.04512291352          32.4903879259459       6.21586252565961    
                  AB12345-BRA-11-id-217     SCREENING           215.367414313054         20.8879942219526       6.55883385955605    
                                          CYCLE 1 DAY 1         272.094354596647         34.2812274648873       5.04441608634882    
                                          CYCLE 1 DAY 2         174.183265394136          23.04243406023        4.07416508597243    
                  AB12345-BRA-11-id-345     SCREENING           235.746948097021         26.5740342881269       5.52059967823211    
                                          CYCLE 1 DAY 1         228.51025073098          39.7523164840323       6.32996327499752    
                                          CYCLE 1 DAY 2         120.712762389698          24.37143486359        5.02620823564574    
                  AB12345-BRA-11-id-397     SCREENING           165.925716319045         21.8770819414152       6.3713157196375     
                                          CYCLE 1 DAY 1         201.536920713046         36.5841424116449       4.32440907316618    
Experimental use!

WebR is a tool allowing you to run R code in the web browser. Modify the code below and click run to see the results. Alternatively, copy the code and click here to open WebR in a new tab.

Code
library(dplyr)
library(rlistings)

drug_a <- "Plasma Drug X"
spec <- "Plasma"

adpp <- random.cdisc.data::cadpp
adpp_x <- adpp %>% filter(
  PPCAT == drug_a,
  PPSPEC == spec
)

out <- adpp_x %>%
  mutate(PARAM = paste0(PARAM, " (", AVALU, ")")) %>%
  select(TRT01A, USUBJID, AVISIT, PARAM, AVAL) %>%
  tidyr::pivot_wider(
    id_cols = c(TRT01A, USUBJID, AVISIT),
    names_from = PARAM,
    values_from = AVAL
  )

var_labels(out) <- names(out)
out <- out %>% var_relabel(
  TRT01A = "Treatment Group",
  USUBJID = "Subject ID",
  AVISIT = "Visit"
)

Reproducibility

Timestamp

[1] "2025-07-09 17:35:46 UTC"

Session Info

─ Session info ───────────────────────────────────────────────────────────────
 setting  value
 version  R version 4.5.0 (2025-04-11)
 os       Ubuntu 24.04.2 LTS
 system   x86_64, linux-gnu
 ui       X11
 language (EN)
 collate  en_US.UTF-8
 ctype    en_US.UTF-8
 tz       Etc/UTC
 date     2025-07-09
 pandoc   3.7.0.2 @ /usr/bin/ (via rmarkdown)
 quarto   1.7.32 @ /usr/local/bin/quarto

─ Packages ───────────────────────────────────────────────────────────────────
 package           * version date (UTC) lib source
 backports           1.5.0   2024-05-23 [1] RSPM
 brio                1.1.5   2024-04-24 [1] RSPM
 checkmate           2.3.2   2024-07-29 [1] RSPM
 cli                 3.6.5   2025-04-23 [1] RSPM
 codetools           0.2-20  2024-03-31 [2] CRAN (R 4.5.0)
 curl                6.4.0   2025-06-22 [1] RSPM
 digest              0.6.37  2024-08-19 [1] RSPM
 dplyr             * 1.1.4   2023-11-17 [1] RSPM
 evaluate            1.0.4   2025-06-18 [1] RSPM
 fastmap             1.2.0   2024-05-15 [1] RSPM
 formatters        * 0.5.11  2025-04-09 [1] RSPM
 generics            0.1.4   2025-05-09 [1] RSPM
 glue                1.8.0   2024-09-30 [1] RSPM
 htmltools           0.5.8.1 2024-04-04 [1] RSPM
 htmlwidgets         1.6.4   2023-12-06 [1] RSPM
 jsonlite            2.0.0   2025-03-27 [1] RSPM
 knitr               1.50    2025-03-16 [1] RSPM
 lifecycle           1.0.4   2023-11-07 [1] RSPM
 magrittr            2.0.3   2022-03-30 [1] RSPM
 pillar              1.11.0  2025-07-04 [1] RSPM
 pkgcache            2.2.4   2025-05-26 [1] RSPM
 pkgconfig           2.0.3   2019-09-22 [1] RSPM
 processx            3.8.6   2025-02-21 [1] RSPM
 ps                  1.9.1   2025-04-12 [1] RSPM
 purrr               1.0.4   2025-02-05 [1] RSPM
 R6                  2.6.1   2025-02-15 [1] RSPM
 random.cdisc.data   0.3.16  2024-10-10 [1] RSPM
 rlang               1.1.6   2025-04-11 [1] RSPM
 rlistings         * 0.2.12  2025-06-15 [1] RSPM
 rmarkdown           2.29    2024-11-04 [1] RSPM
 sessioninfo         1.2.3   2025-02-05 [1] any (@1.2.3)
 stringi             1.8.7   2025-03-27 [1] RSPM
 stringr             1.5.1   2023-11-14 [1] RSPM
 testthat            3.2.3   2025-01-13 [1] RSPM
 tibble            * 3.3.0   2025-06-08 [1] RSPM
 tidyr               1.3.1   2024-01-24 [1] RSPM
 tidyselect          1.2.1   2024-03-11 [1] RSPM
 vctrs               0.6.5   2023-12-01 [1] RSPM
 withr               3.0.2   2024-10-28 [1] RSPM
 xfun                0.52    2025-04-02 [1] RSPM
 yaml                2.3.10  2024-07-26 [1] RSPM

 [1] /usr/local/lib/R/site-library
 [2] /usr/local/lib/R/library
 [3] /github/home/R/x86_64-pc-linux-gnu-library/4.5
 * ── Packages attached to the search path.

──────────────────────────────────────────────────────────────────────────────

.lock file

Download the .lock file and use renv::restore() on it to recreate environment used to generate this website.

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PKCL02
PKPL02
Source Code
---
title: PKPL01
subtitle: Listing of Drug A Plasma PK Parameters
---

------------------------------------------------------------------------

{{< include ../../_utils/envir_hook.qmd >}}

```{r setup, echo = FALSE, warning = FALSE, message = FALSE}
library(dplyr)
library(rlistings)

drug_a <- "Plasma Drug X"
spec <- "Plasma"

adpp <- random.cdisc.data::cadpp
adpp_x <- adpp %>% filter(
  PPCAT == drug_a,
  PPSPEC == spec
)

out <- adpp_x %>%
  mutate(PARAM = paste0(PARAM, " (", AVALU, ")")) %>%
  select(TRT01A, USUBJID, AVISIT, PARAM, AVAL) %>%
  tidyr::pivot_wider(
    id_cols = c(TRT01A, USUBJID, AVISIT),
    names_from = PARAM,
    values_from = AVAL
  )

var_labels(out) <- names(out)
out <- out %>% var_relabel(
  TRT01A = "Treatment Group",
  USUBJID = "Subject ID",
  AVISIT = "Visit"
)
```

```{r include = FALSE}
webr_code_labels <- c("setup")
```

{{< include ../../_utils/webr_no_include.qmd >}}

## Output

:::: panel-tabset
## Standard Listing

::: {.panel-tabset .nav-justified group="webr"}
## {{< fa regular file-lines sm fw >}} Preview

```{r lsting, test = list(lsting = "lsting")}
lsting <- as_listing(
  out,
  key_cols = c("TRT01A", "USUBJID", "AVISIT"),
  disp_cols = names(out),
  main_title = paste("Listing of", drug_a, spec, "PK Parameters, PK Population\nProtocol: xxnnnnn"),
  subtitles = paste("Analyte:", drug_a)
)

head(lsting, 20)
```

```{r include = FALSE}
webr_code_labels <- c("lsting")
```

{{< include ../../_utils/webr.qmd >}}
:::

## Data Setup

```{r setup}
#| code-fold: show
```
::::

{{< include ../../_utils/save_results.qmd >}}

{{< include ../../repro.qmd >}}

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