TLG Catalog - Stable
  • Stable
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  1. Listings
  2. Disposition
  3. DSL02
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  • Appendix
    • Reproducibility

  • Index

On this page

  • Output
  • Reproducibility
    • Timestamp
    • Session Info
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  1. Listings
  2. Disposition
  3. DSL02

DSL02

Listing of Patients Who Discontinued Early from Study


Output

  • Standard Listing
  • Data Setup
  • Preview
  • Try this using WebR
Code
lsting <- as_listing(
  out,
  key_cols = "TRT01A",
  disp_cols = names(out),
  main_title = "Listing of Patients Who Discontinued Early from Study"
)

head(lsting, 20)
Listing of Patients Who Discontinued Early from Study

——————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
                                                                                                                          Day of Study                                        
                                                                                                                         Discontinuation     Day of Study                     
                                                                                      Date of First     Day of Last     Relative to First   Discontinuation                   
                                                                                        Study Drug       Study Drug        Study Drug         Relative to        Reason for   
  Treatment      Center/Patient ID                    Age/Sex/Race                    Administration   Administration    Administration      Randomization    Discontinuation 
——————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
  A: Drug X         CHN-1/id-62                        36/F/WHITE                       2020-11-22          455                454                455              DEATH      
  B: Placebo        CHN-9/id-11      28/F/NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER     2021-01-27          388                387                388              DEATH      
C: Combination     USA-11/id-136                       38/F/ASIAN                       2019-10-02          865                864                868              DEATH      
                   USA-11/id-100                       40/F/ASIAN                       2020-03-10          705                705                707         LACK OF EFFICACY
                   CHN-11/id-91              44/M/BLACK OR AFRICAN AMERICAN             2020-05-29          625                625                626              DEATH      
Experimental use!

WebR is a tool allowing you to run R code in the web browser. Modify the code below and click run to see the results. Alternatively, copy the code and click here to open WebR in a new tab.

Code
library(dplyr)
library(rlistings)

adsl <- random.cdisc.data::cadsl

out <- adsl %>%
  filter(AEWITHFL == "Y") %>%
  mutate(
    ID = paste(SITEID, SUBJID, sep = "/"),
    ASR = paste(AGE, SEX, RACE, sep = "/"),
    DISCONT = ifelse(!is.na(DCSREAS) & EOSSTT != "COMPLETED", "Yes", "No"),
    SSADTM = as.POSIXct(
      strftime(TRTSDTM, format = "%Y-%m-%d %H:%M:%S"),
      format = "%Y-%m-%d",
      tz = "UTC"
    ),
    SSAEDY = as.numeric(ceiling(difftime(EOSDT, SSADTM, units = "days"))),
    RANDEDY = as.numeric(ceiling(difftime(EOSDT, RANDDT, units = "days"))),
  ) %>%
  filter(DISCONT == "Yes") %>%
  select(ID, ASR, TRT01A, SSADTM, EOSDY, SSAEDY, RANDEDY, DCSREAS)

var_labels(out) <- c(
  ID = "Center/Patient ID",
  ASR = "Age/Sex/Race",
  TRT01A = "Treatment",
  SSADTM = "Date of First\nStudy Drug\nAdministration",
  EOSDY = "Day of Last\nStudy Drug\nAdministration",
  SSAEDY = "Day of Study\nDiscontinuation\nRelative to First\nStudy Drug\nAdministration",
  RANDEDY = "Day of Study\nDiscontinuation\nRelative to\nRandomization",
  DCSREAS = "Reason for\nDiscontinuation"
)

Reproducibility

Timestamp

[1] "2025-07-05 17:29:33 UTC"

Session Info

─ Session info ───────────────────────────────────────────────────────────────
 setting  value
 version  R version 4.5.0 (2025-04-11)
 os       Ubuntu 24.04.2 LTS
 system   x86_64, linux-gnu
 ui       X11
 language (EN)
 collate  en_US.UTF-8
 ctype    en_US.UTF-8
 tz       Etc/UTC
 date     2025-07-05
 pandoc   3.7.0.2 @ /usr/bin/ (via rmarkdown)
 quarto   1.7.32 @ /usr/local/bin/quarto

─ Packages ───────────────────────────────────────────────────────────────────
 package           * version date (UTC) lib source
 backports           1.5.0   2024-05-23 [1] RSPM
 brio                1.1.5   2024-04-24 [1] RSPM
 checkmate           2.3.2   2024-07-29 [1] RSPM
 cli                 3.6.5   2025-04-23 [1] RSPM
 codetools           0.2-20  2024-03-31 [2] CRAN (R 4.5.0)
 curl                6.4.0   2025-06-22 [1] RSPM
 digest              0.6.37  2024-08-19 [1] RSPM
 dplyr             * 1.1.4   2023-11-17 [1] RSPM
 evaluate            1.0.4   2025-06-18 [1] RSPM
 fastmap             1.2.0   2024-05-15 [1] RSPM
 formatters        * 0.5.11  2025-04-09 [1] RSPM
 generics            0.1.4   2025-05-09 [1] RSPM
 glue                1.8.0   2024-09-30 [1] RSPM
 htmltools           0.5.8.1 2024-04-04 [1] RSPM
 htmlwidgets         1.6.4   2023-12-06 [1] RSPM
 jsonlite            2.0.0   2025-03-27 [1] RSPM
 knitr               1.50    2025-03-16 [1] RSPM
 lifecycle           1.0.4   2023-11-07 [1] RSPM
 magrittr            2.0.3   2022-03-30 [1] RSPM
 pillar              1.11.0  2025-07-04 [1] RSPM
 pkgcache            2.2.4   2025-05-26 [1] RSPM
 pkgconfig           2.0.3   2019-09-22 [1] RSPM
 processx            3.8.6   2025-02-21 [1] RSPM
 ps                  1.9.1   2025-04-12 [1] RSPM
 R6                  2.6.1   2025-02-15 [1] RSPM
 random.cdisc.data   0.3.16  2024-10-10 [1] RSPM
 rlang               1.1.6   2025-04-11 [1] RSPM
 rlistings         * 0.2.12  2025-06-15 [1] RSPM
 rmarkdown           2.29    2024-11-04 [1] RSPM
 sessioninfo         1.2.3   2025-02-05 [1] any (@1.2.3)
 stringi             1.8.7   2025-03-27 [1] RSPM
 stringr             1.5.1   2023-11-14 [1] RSPM
 testthat            3.2.3   2025-01-13 [1] RSPM
 tibble            * 3.3.0   2025-06-08 [1] RSPM
 tidyselect          1.2.1   2024-03-11 [1] RSPM
 vctrs               0.6.5   2023-12-01 [1] RSPM
 withr               3.0.2   2024-10-28 [1] RSPM
 xfun                0.52    2025-04-02 [1] RSPM
 yaml                2.3.10  2024-07-26 [1] RSPM

 [1] /usr/local/lib/R/site-library
 [2] /usr/local/lib/R/library
 [3] /github/home/R/x86_64-pc-linux-gnu-library/4.5
 * ── Packages attached to the search path.

──────────────────────────────────────────────────────────────────────────────

.lock file

Download the .lock file and use renv::restore() on it to recreate environment used to generate this website.

Download

DSL01
EGL01
Source Code
---
title: DSL02
subtitle: Listing of Patients Who Discontinued Early from Study
---

------------------------------------------------------------------------

{{< include ../../_utils/envir_hook.qmd >}}

```{r setup, echo = FALSE, warning = FALSE, message = FALSE}
library(dplyr)
library(rlistings)

adsl <- random.cdisc.data::cadsl

out <- adsl %>%
  filter(AEWITHFL == "Y") %>%
  mutate(
    ID = paste(SITEID, SUBJID, sep = "/"),
    ASR = paste(AGE, SEX, RACE, sep = "/"),
    DISCONT = ifelse(!is.na(DCSREAS) & EOSSTT != "COMPLETED", "Yes", "No"),
    SSADTM = as.POSIXct(
      strftime(TRTSDTM, format = "%Y-%m-%d %H:%M:%S"),
      format = "%Y-%m-%d",
      tz = "UTC"
    ),
    SSAEDY = as.numeric(ceiling(difftime(EOSDT, SSADTM, units = "days"))),
    RANDEDY = as.numeric(ceiling(difftime(EOSDT, RANDDT, units = "days"))),
  ) %>%
  filter(DISCONT == "Yes") %>%
  select(ID, ASR, TRT01A, SSADTM, EOSDY, SSAEDY, RANDEDY, DCSREAS)

var_labels(out) <- c(
  ID = "Center/Patient ID",
  ASR = "Age/Sex/Race",
  TRT01A = "Treatment",
  SSADTM = "Date of First\nStudy Drug\nAdministration",
  EOSDY = "Day of Last\nStudy Drug\nAdministration",
  SSAEDY = "Day of Study\nDiscontinuation\nRelative to First\nStudy Drug\nAdministration",
  RANDEDY = "Day of Study\nDiscontinuation\nRelative to\nRandomization",
  DCSREAS = "Reason for\nDiscontinuation"
)
```

```{r include = FALSE}
webr_code_labels <- c("setup")
```

{{< include ../../_utils/webr_no_include.qmd >}}

## Output

:::: panel-tabset
## Standard Listing

::: {.panel-tabset .nav-justified group="webr"}
## {{< fa regular file-lines sm fw >}} Preview

```{r lsting, test = list(lsting = "lsting")}
lsting <- as_listing(
  out,
  key_cols = "TRT01A",
  disp_cols = names(out),
  main_title = "Listing of Patients Who Discontinued Early from Study"
)

head(lsting, 20)
```

```{r include = FALSE}
webr_code_labels <- c("lsting")
```

{{< include ../../_utils/webr.qmd >}}
:::

## Data Setup

```{r setup}
#| code-fold: show
```
::::

{{< include ../../_utils/save_results.qmd >}}

{{< include ../../repro.qmd >}}

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