lsting <-as_listing( out,key_cols =c("USUBJID", "VISIT"),disp_cols =names(out),main_title =paste0("Listing of Anti-", drugcd, " Antibody Data for Patients with At Least One ADA Sample Datum by Treatment, ","PK Population\nProtocol: ", drug_a ),subtitles =paste("\nTreatment Group:", trt),main_footer ="(1) Minimum reportable titer = 1.10 (example only)(2) Minimum reportable titer = 1.10 (example only)(3) Minimum reportable concentration = 3.0 (example only)BLQ = Below Limit of Quantitation, LTR = Lower than Reportable, N/A = Not Applicable, N.C. = Not Calculable,ADA = Anti-Drug Antibodies (is also referred to as ATA, or Anti-Therapeutic Antibodies)ROXXXXXXX is also known as [drug]")tail(lsting, 50)[1:24, ]
Listing of Anti-R1800000 Antibody Data for Patients with At Least One ADA Sample Datum by Treatment, PK Population
Protocol: A: Drug X Antibody
Treatment Group: A: Drug X
———————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
ADA NAb Sample Patient Patient
Nominal Titer Titer Sample Neutralizing Treatment Treatment Drug
Time Units Units ADA Antibody Emergent ADA Emergent NAb Concentration
Subject ID Visit Timepoint (hr) (1) (2) Result (NAb) Result Status Status (ug/mL) (3)
———————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
AB12345-PAK-11-id-145 Day 1 Predose 0.00 N/A N/A Negative Negative Negative Negative N/A
Day 2 24H 1.00 N/A N/A Negative Negative N/A
AB12345-PAK-11-id-187 Day 1 Predose 0.00 N/A N/A Negative Negative Positive Negative N/A
Day 2 24H 1.00 1.16 1.16 Positive Positive N/A
AB12345-PAK-11-id-268 Day 1 Predose 0.00 N/A N/A Negative Negative Negative Negative N/A
Day 2 24H 1.00 N/A N/A Negative Negative N/A
AB12345-PAK-11-id-68 Day 1 Predose 0.00 1.08 1.08 Positive Positive Positive Negative N/A
Day 2 24H 1.00 1.19 1.19 Positive Positive N/A
AB12345-PAK-12-id-328 Day 1 Predose 0.00 1.11 1.11 Positive Positive Negative Negative N/A
Day 2 24H 1.00 N/A N/A Negative Negative N/A
AB12345-PAK-12-id-85 Day 1 Predose 0.00 1.06 1.06 Positive Positive Positive Negative N/A
Day 2 24H 1.00 1.35 1.35 Positive Positive N/A
AB12345-PAK-13-id-251 Day 1 Predose 0.00 N/A N/A Negative Negative Positive Negative N/A
Day 2 24H 1.00 1.14 1.14 Positive Positive N/A
AB12345-PAK-14-id-117 Day 1 Predose 0.00 1.04 1.04 Positive Positive Positive Negative N/A
Day 2 24H 1.00 1.06 1.06 Positive Positive N/A
AB12345-PAK-15-id-314 Day 1 Predose 0.00 N/A N/A Negative Negative Positive Negative N/A
Day 2 24H 1.00 1.02 1.02 Positive Positive N/A
AB12345-PAK-2-id-213 Day 1 Predose 0.00 1.24 1.24 Positive Positive Negative Negative N/A
Day 2 24H 1.00 N/A N/A Negative Negative N/A
AB12345-RUS-1-id-52 Day 1 Predose 0.00 N/A N/A Negative Negative Positive Negative N/A
Day 2 24H 1.00 1.22 1.22 Positive Positive N/A
AB12345-RUS-13-id-70 Day 1 Predose 0.00 N/A N/A Negative Negative Negative Negative N/A
Day 2 24H 1.00 N/A N/A Negative Negative N/A
———————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
(1) Minimum reportable titer = 1.10 (example only)
(2) Minimum reportable titer = 1.10 (example only)
(3) Minimum reportable concentration = 3.0 (example only)
BLQ = Below Limit of Quantitation, LTR = Lower than Reportable, N/A = Not Applicable, N.C. = Not Calculable,
ADA = Anti-Drug Antibodies (is also referred to as ATA, or Anti-Therapeutic Antibodies)
ROXXXXXXX is also known as [drug]
Experimental use!
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```{r, echo = FALSE, results = “asis”, opts.label = “skip_if_testing”} if (!exists(“webr_code_labels”)) { webr_code_labels <- character(0L) } if (!all(webr_code_labels %in% knitr::all_labels())) { stop(sprintf( “Not all of provided labels exist in the current document!found labels are: %s.”, paste0(setdiff(webr_code_labels, knitr::all_labels()), collapse = “,”) )) }