DSL01

Listing of Patients with Study Drug Withdrawn Due to Adverse Events

Standard Listing
Data Setup

Preview
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Code

lsting <- as_listing(
  out,
  key_cols = "TRT01A",
  disp_cols = names(out),
  main_title = "Listing of Patients with Study Drug Withdrawn Due to Adverse Events"
)

head(lsting, 20)

Listing of Patients with Study Drug Withdrawn Due to Adverse Events

————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
                                                                                      Date of First                                     
                                                                                        Study Drug       Study Day       Discontinued   
  Treatment      Center/Patient ID                    Age/Sex/Race                    Administration   of Withdrawal   Early from Study?
————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
  A: Drug X        RUS-18/id-359             47/F/BLACK OR AFRICAN AMERICAN             08JUN2019          1096               No        
                    BRA-1/id-42              36/M/BLACK OR AFRICAN AMERICAN             01JAN2020           NA                No        
                   CHN-11/id-256                       23/M/ASIAN                       17MAR2020          1096               No        
                    CHN-1/id-26                        29/M/WHITE                       16JUL2020          1096               No        
                    CHN-1/id-62                        36/F/WHITE                       22NOV2020           455               Yes       
  B: Placebo        CHN-7/id-28          40/M/AMERICAN INDIAN OR ALASKA NATIVE          11MAR2019          1096               No        
                   CHN-13/id-102                       37/M/ASIAN                       23MAR2019          1096               No        
                   CHN-3/id-333              30/F/BLACK OR AFRICAN AMERICAN             13JAN2020           NA                No        
                   USA-12/id-226                       30/M/WHITE                       29JAN2020           NA                No        
                   CHN-9/id-147                        26/F/ASIAN                       06FEB2020           NA                No        
                   USA-11/id-157                       50/M/WHITE                       14JUN2020          1096               No        
                    CHN-9/id-11      28/F/NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER     27JAN2021           388               Yes       
C: Combination     CHN-15/id-262             35/M/BLACK OR AFRICAN AMERICAN             26FEB2019          1096               No        
                   NGA-11/id-173             24/F/BLACK OR AFRICAN AMERICAN             10MAR2019          1096               No        
                   CHN-11/id-263                       34/F/ASIAN                       03APR2019          1096               No        
                   PAK-2/id-191          38/F/AMERICAN INDIAN OR ALASKA NATIVE          07APR2019          1096               No        
                   USA-11/id-136                       38/F/ASIAN                       02OCT2019           865               Yes       
                   CHN-17/id-31                        35/F/ASIAN                       17NOV2019           NA                No        
                   BRA-11/id-237                       64/F/ASIAN                       10MAR2020          1096               No        
                   USA-11/id-100                       40/F/ASIAN                       10MAR2020           705               Yes

Experimental use!

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Code

library(dplyr)
library(rlistings)

adsl <- random.cdisc.data::cadsl

out <- adsl %>%
  filter(AEWITHFL == "Y") %>%
  mutate(
    ID = paste(SITEID, SUBJID, sep = "/"),
    ASR = paste(AGE, SEX, RACE, sep = "/"),
    SSADM = toupper(format(as.Date(TRTSDTM), format = "%d%b%Y")),
    STDWD = as.numeric(ceiling(difftime(TRTEDTM, TRTSDTM, units = "days"))),
    DISCONT = ifelse(!is.na(DCSREAS) & toupper(EOSSTT) == "DISCONTINUED", "Yes", "No")
  ) %>%
  select(ID, ASR, TRT01A, SSADM, STDWD, DISCONT)

var_labels(out) <- c(
  ID = "Center/Patient ID",
  ASR = "Age/Sex/Race",
  TRT01A = "Treatment",
  SSADM = "Date of First\nStudy Drug\nAdministration",
  STDWD = "Study Day\nof Withdrawal",
  DISCONT = "Discontinued\nEarly from Study?"
)

Reproducibility

Timestamp

[1] "2024-11-02 18:24:35 UTC"

Session Info

─ Session info ───────────────────────────────────────────────────────────────
 setting  value
 version  R version 4.4.1 (2024-06-14)
 os       Ubuntu 22.04.5 LTS
 system   x86_64, linux-gnu
 ui       X11
 language (EN)
 collate  en_US.UTF-8
 ctype    en_US.UTF-8
 tz       Etc/UTC
 date     2024-11-02
 pandoc   3.4 @ /usr/bin/ (via rmarkdown)

─ Packages ───────────────────────────────────────────────────────────────────
 package           * version     date (UTC) lib source
 backports           1.5.0       2024-05-23 [1] CRAN (R 4.4.1)
 brio                1.1.5       2024-04-24 [1] CRAN (R 4.4.1)
 checkmate           2.3.2       2024-07-29 [1] CRAN (R 4.4.1)
 cli                 3.6.3       2024-06-21 [1] CRAN (R 4.4.1)
 codetools           0.2-20      2024-03-31 [2] CRAN (R 4.4.1)
 digest              0.6.37      2024-08-19 [1] CRAN (R 4.4.1)
 dplyr             * 1.1.4       2023-11-17 [1] CRAN (R 4.4.1)
 evaluate            1.0.1       2024-10-10 [1] CRAN (R 4.4.1)
 fansi               1.0.6       2023-12-08 [1] CRAN (R 4.4.1)
 fastmap             1.2.0       2024-05-15 [1] CRAN (R 4.4.1)
 formatters        * 0.5.9.9003  2024-11-02 [1] git2r (https://github.com/insightsengineering/formatters.git@84e8c3e)
 generics            0.1.3       2022-07-05 [1] CRAN (R 4.4.1)
 glue                1.8.0       2024-09-30 [1] CRAN (R 4.4.1)
 htmltools           0.5.8.1     2024-04-04 [1] CRAN (R 4.4.1)
 htmlwidgets         1.6.4       2023-12-06 [1] CRAN (R 4.4.1)
 jsonlite            1.8.9       2024-09-20 [1] CRAN (R 4.4.1)
 knitr               1.48        2024-07-07 [1] CRAN (R 4.4.1)
 lifecycle           1.0.4       2023-11-07 [1] CRAN (R 4.4.1)
 magrittr            2.0.3       2022-03-30 [1] CRAN (R 4.4.1)
 pillar              1.9.0       2023-03-22 [1] CRAN (R 4.4.1)
 pkgconfig           2.0.3       2019-09-22 [1] CRAN (R 4.4.1)
 R6                  2.5.1       2021-08-19 [1] CRAN (R 4.4.1)
 random.cdisc.data   0.3.16.9001 2024-11-02 [1] git2r (https://github.com/insightsengineering/random.cdisc.data.git@a65bfbe)
 rlang               1.1.4       2024-06-04 [1] CRAN (R 4.4.1)
 rlistings         * 0.2.9.9008  2024-11-02 [1] git2r (https://github.com/insightsengineering/rlistings.git@f6bb1fb)
 rmarkdown           2.28        2024-08-17 [1] CRAN (R 4.4.1)
 sessioninfo         1.2.2       2021-12-06 [1] CRAN (R 4.4.1)
 stringi             1.8.4       2024-05-06 [1] CRAN (R 4.4.1)
 stringr             1.5.1       2023-11-14 [1] CRAN (R 4.4.1)
 testthat            3.2.1.1     2024-04-14 [1] CRAN (R 4.4.1)
 tibble            * 3.2.1       2023-03-20 [1] CRAN (R 4.4.1)
 tidyselect          1.2.1       2024-03-11 [1] CRAN (R 4.4.1)
 utf8                1.2.4       2023-10-22 [1] CRAN (R 4.4.1)
 vctrs               0.6.5       2023-12-01 [1] CRAN (R 4.4.1)
 withr               3.0.1       2024-07-31 [1] CRAN (R 4.4.1)
 xfun                0.48        2024-10-03 [1] CRAN (R 4.4.1)
 yaml                2.3.10      2024-07-26 [1] CRAN (R 4.4.1)

 [1] /usr/local/lib/R/site-library
 [2] /usr/local/lib/R/library

──────────────────────────────────────────────────────────────────────────────

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Reproducibility

Timestamp

Session Info

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