AET03 Table 1 (Default) Advert Events by Greatest Intensity Table 1.

An adverse events table categorized by System Organ Class, Dictionary-Derived Term and Greatest intensity.

Usage

aet03_main(adam_db, arm_var = "ACTARM", lbl_overall = NULL, ...)

aet03_pre(adam_db, ...)

aet03_post(tlg, prune_0 = TRUE, ...)

aet03

Format

An object of class chevron_t of length 1.

Arguments

adam_db: (list of data.frames) object containing the ADaM datasets
arm_var: (string) variable used for column splitting
lbl_overall: (string) label used for overall column, if set to NULL the overall column is omitted
...: not used.
tlg: (TableTree, Listing or ggplot) object typically produced by a main function.
prune_0: (flag) remove 0 count rows

Value

the main function returns an rtables object.

the preprocessing function returns a list of data.frame.

the postprocessing function returns an rtables object or an ElementaryTable (null report).

Details

Default Adverse Events by Greatest Intensity table.
Numbers represent absolute numbers of patients and fraction of N.
Remove zero-count rows unless overridden with prune_0 = FALSE.
Split columns by arm.
Does not include a total column by default.
Sort by Body System or Organ Class (SOC) and Dictionary-Derived Term (PT).

Functions

aet03_main(): Main TLG function
aet03_pre(): Preprocessing
aet03_post(): Postprocessing

Note

adam_db object must contain an adae table with the columns "AEBODSYS", "AEDECOD" and "ASEV".

Examples

run(aet03, syn_data)
#>   MedDRA System Organ Class   A: Drug X    B: Placebo   C: Combination
#>     MedDRA Preferred Term       (N=15)       (N=15)         (N=15)    
#>   ————————————————————————————————————————————————————————————————————
#>   - Any Intensity -           13 (86.7%)   14 (93.3%)     15 (100%)   
#>   MILD                            0         1 (6.7%)       1 (6.7%)   
#>   MODERATE                    2 (13.3%)    3 (20.0%)      2 (13.3%)   
#>   SEVERE                      11 (73.3%)   10 (66.7%)     12 (80.0%)  
#>   cl B.2                                                              
#>     - Any Intensity -         11 (73.3%)   8 (53.3%)      10 (66.7%)  
#>     MILD                      6 (40.0%)    2 (13.3%)      5 (33.3%)   
#>     MODERATE                  5 (33.3%)    6 (40.0%)      5 (33.3%)   
#>     dcd B.2.2.3.1                                                     
#>       - Any Intensity -       8 (53.3%)    6 (40.0%)      7 (46.7%)   
#>       MILD                    8 (53.3%)    6 (40.0%)      7 (46.7%)   
#>     dcd B.2.1.2.1                                                     
#>       - Any Intensity -       5 (33.3%)    6 (40.0%)      5 (33.3%)   
#>       MODERATE                5 (33.3%)    6 (40.0%)      5 (33.3%)   
#>   cl D.1                                                              
#>     - Any Intensity -         9 (60.0%)    5 (33.3%)      11 (73.3%)  
#>     MODERATE                  5 (33.3%)     1 (6.7%)      4 (26.7%)   
#>     SEVERE                    4 (26.7%)    4 (26.7%)      7 (46.7%)   
#>     dcd D.1.1.1.1                                                     
#>       - Any Intensity -       4 (26.7%)    4 (26.7%)      7 (46.7%)   
#>       SEVERE                  4 (26.7%)    4 (26.7%)      7 (46.7%)   
#>     dcd D.1.1.4.2                                                     
#>       - Any Intensity -       6 (40.0%)    2 (13.3%)      7 (46.7%)   
#>       MODERATE                6 (40.0%)    2 (13.3%)      7 (46.7%)   
#>   cl A.1                                                              
#>     - Any Intensity -         7 (46.7%)    6 (40.0%)      10 (66.7%)  
#>     MILD                      2 (13.3%)        0          4 (26.7%)   
#>     MODERATE                  5 (33.3%)    6 (40.0%)      6 (40.0%)   
#>     dcd A.1.1.1.2                                                     
#>       - Any Intensity -       5 (33.3%)    6 (40.0%)      6 (40.0%)   
#>       MODERATE                5 (33.3%)    6 (40.0%)      6 (40.0%)   
#>     dcd A.1.1.1.1                                                     
#>       - Any Intensity -       3 (20.0%)     1 (6.7%)      6 (40.0%)   
#>       MILD                    3 (20.0%)     1 (6.7%)      6 (40.0%)   
#>   cl B.1                                                              
#>     - Any Intensity -         5 (33.3%)    6 (40.0%)      8 (53.3%)   
#>     SEVERE                    5 (33.3%)    6 (40.0%)      8 (53.3%)   
#>     dcd B.1.1.1.1                                                     
#>       - Any Intensity -       5 (33.3%)    6 (40.0%)      8 (53.3%)   
#>       SEVERE                  5 (33.3%)    6 (40.0%)      8 (53.3%)   
#>   cl C.2                                                              
#>     - Any Intensity -         6 (40.0%)    4 (26.7%)      8 (53.3%)   
#>     MODERATE                  6 (40.0%)    4 (26.7%)      8 (53.3%)   
#>     dcd C.2.1.2.1                                                     
#>       - Any Intensity -       6 (40.0%)    4 (26.7%)      8 (53.3%)   
#>       MODERATE                6 (40.0%)    4 (26.7%)      8 (53.3%)   
#>   cl D.2                                                              
#>     - Any Intensity -         2 (13.3%)    5 (33.3%)      7 (46.7%)   
#>     MILD                      2 (13.3%)    5 (33.3%)      7 (46.7%)   
#>     dcd D.2.1.5.3                                                     
#>       - Any Intensity -       2 (13.3%)    5 (33.3%)      7 (46.7%)   
#>       MILD                    2 (13.3%)    5 (33.3%)      7 (46.7%)   
#>   cl C.1                                                              
#>     - Any Intensity -         4 (26.7%)    4 (26.7%)      5 (33.3%)   
#>     SEVERE                    4 (26.7%)    4 (26.7%)      5 (33.3%)   
#>     dcd C.1.1.1.3                                                     
#>       - Any Intensity -       4 (26.7%)    4 (26.7%)      5 (33.3%)   
#>       SEVERE                  4 (26.7%)    4 (26.7%)      5 (33.3%)