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chevron is a collection of function to create standard tables, listings, and graphs for clinical trials reporting.

Installation

It is recommended that you create and use a GitHub PAT to install the latest version of this package. Once you have the PAT, run the following:

Sys.setenv(GITHUB_PAT = "your_access_token_here")
if (!require("remotes")) install.packages("remotes")
remotes::install_github("insightsengineering/chevron@*release")

Usage

library(chevron)

data(syn_data)
run(aet02_1, syn_data)

which returns

  MedDRA System Organ Class                                     A: Drug X    B: Placebo    C: Combination
    MedDRA Preferred Term                                        (N=134)       (N=134)        (N=132)    
  ———————————————————————————————————————————————————————————————————————————————————————————————————————
  Total number of patients with at least one adverse event     122 (91.0%)   123 (91.8%)    120 (90.9%)  
  Overall total number of events                                   609           622            703      
  cl A.1                                                                                                 
    Total number of patients with at least one adverse event   78 (58.2%)    75 (56.0%)      89 (67.4%)  
    Total number of events                                         132           130            160      
    dcd A.1.1.1.1                                              50 (37.3%)    45 (33.6%)      63 (47.7%)  
    dcd A.1.1.1.2                                              48 (35.8%)    48 (35.8%)      50 (37.9%)  
  cl B.2                                                                                                 
    Total number of patients with at least one adverse event   79 (59.0%)    74 (55.2%)      85 (64.4%)  
    Total number of events                                         129           138            143      
    dcd B.2.2.3.1                                              48 (35.8%)    54 (40.3%)      51 (38.6%)  
    dcd B.2.1.2.1                                              49 (36.6%)    44 (32.8%)      52 (39.4%)  
  cl D.1                                                                                                 
    Total number of patients with at least one adverse event   79 (59.0%)    67 (50.0%)      80 (60.6%)  
    Total number of events                                         127           106            135      
    dcd D.1.1.1.1                                              50 (37.3%)    42 (31.3%)      51 (38.6%)  
    dcd D.1.1.4.2                                              48 (35.8%)    42 (31.3%)      50 (37.9%)  
  cl D.2                                                                                                 
    Total number of patients with at least one adverse event   47 (35.1%)    58 (43.3%)      57 (43.2%)  
    Total number of events                                         62            72              74      
    dcd D.2.1.5.3                                              47 (35.1%)    58 (43.3%)      57 (43.2%)  
  cl B.1                                                                                                 
    Total number of patients with at least one adverse event   47 (35.1%)    49 (36.6%)      43 (32.6%)  
    Total number of events                                         56            60              62      
    dcd B.1.1.1.1                                              47 (35.1%)    49 (36.6%)      43 (32.6%)  
  cl C.2                                                                                                 
    Total number of patients with at least one adverse event   35 (26.1%)    48 (35.8%)      55 (41.7%)  
    Total number of events                                         48            53              65      
    dcd C.2.1.2.1                                              35 (26.1%)    48 (35.8%)      55 (41.7%)  
  cl C.1                                                                                                 
    Total number of patients with at least one adverse event   43 (32.1%)    46 (34.3%)      43 (32.6%)  
    Total number of events                                         55            63              64      
    dcd C.1.1.1.3                                              43 (32.1%)    46 (34.3%)      43 (32.6%)