AET05_ALL Table 1 (Default) Adverse Event Rate Adjusted for Patient-Years at Risk - All Occurrences.

The AET05_ALL table produces the standard adverse event rate adjusted for patient-years at risk summary considering all occurrences.

Usage

aet05_all_pre(adam_db, dataset = "adsaftte", ...)

aet05_all

Format

An object of class chevron_t of length 1.

Arguments

adam_db: (list of data.frames) object containing the ADaM datasets
dataset: (string) the name of a table in the adam_db object.
...: not used.

Value

the preprocessing function returns a list of data.frame.

Functions

aet05_all_pre(): Preprocessing

Examples

library(dplyr)
library(dunlin)

proc_data <- log_filter(syn_data, PARAMCD == "AETOT1" | PARAMCD == "AEREPTTE", "adsaftte")

run(aet05_all, proc_data)
#>                                                  A: Drug X        B: Placebo      C: Combination 
#>                                                    (N=15)           (N=15)            (N=15)     
#>   ———————————————————————————————————————————————————————————————————————————————————————————————
#>   Number of occurrences of any adverse event                                                     
#>     Total patient-years at risk                     44.4             44.2              44.4      
#>     Number of adverse events observed                29               49                56       
#>     AE rate per 100 patient-years                  65.32            110.76            126.15     
#>     95% CI                                     (41.54, 89.09)   (79.75, 141.77)   (93.11, 159.19)

run(aet05_all, proc_data, conf_level = 0.90, conf_type = "exact")
#>                                                  A: Drug X        B: Placebo      C: Combination 
#>                                                    (N=15)           (N=15)            (N=15)     
#>   ———————————————————————————————————————————————————————————————————————————————————————————————
#>   Number of occurrences of any adverse event                                                     
#>     Total patient-years at risk                     44.4             44.2              44.4      
#>     Number of adverse events observed                29               49                56       
#>     AE rate per 100 patient-years                  65.32            110.76            126.15     
#>     90% CI                                     (46.73, 89.06)   (86.08, 140.53)   (99.76, 157.60)