LBT15
Laboratory Test Shifts to NCI-CTCAE
Grade 3-4 Post-Baseline Table.
Examples
run(lbt15, syn_data)
#> Laboratory Test A: Drug X B: Placebo C: Combination
#> Analysis Toxicity Grade (N=15) (N=15) (N=15)
#> ———————————————————————————————————————————————————————————————————————————————————
#> CHEMISTRY
#> Alanine Aminotransferase Measurement
#> Low 1/8 (12.5%) 0/3 0/9
#> High 0/8 0/2 0/9
#> C-Reactive Protein Measurement
#> Low 0/8 0/3 2/7 (28.6%)
#> High 0/9 0/3 0/8
#> Immunoglobulin A Measurement
#> Low 2/6 (33.3%) 1/9 (11.1%) 0/6
#> High 0/6 0/9 0/7
#> COAGULATION
#> Alanine Aminotransferase Measurement
#> Low 0/5 1/6 (16.7%) 0/5
#> High 0/6 1/7 (14.3%) 0/5
#> C-Reactive Protein Measurement
#> Low 0/6 0/6 0/4
#> High 1/6 (16.7%) 1/7 (14.3%) 0/4
#> Immunoglobulin A Measurement
#> Low 0/8 0/10 0/7
#> High 1/7 (14.3%) 0/10 0/7
#> HEMATOLOGY
#> Alanine Aminotransferase Measurement
#> Low 0/5 0/5 0/4
#> High 0/6 0/4 0/4
#> C-Reactive Protein Measurement
#> Low 0/4 0/4 1/9 (11.1%)
#> High 0/5 0/5 0/10
#> Immunoglobulin A Measurement
#> Low 0/3 0/4 2/8 (25.0%)
#> High 0/4 1/4 (25.0%) 0/8