LBT04 Laboratory Abnormalities Not Present at Baseline Table.

The LBT04 table provides an overview of laboratory abnormalities not present at baseline.

Usage

lbt04_main(
  adam_db,
  arm_var = "ACTARM",
  lbl_overall = NULL,
  analysis_abn_var = "ANRIND",
  baseline_abn_var = "BNRIND",
  row_split_var = "PARCAT1",
  page_var = tail(row_split_var, 1L),
  ...
)

lbt04_pre(adam_db, ...)

lbt04_post(tlg, ...)

lbt04

Format

An object of class chevron_t of length 1.

Arguments

adam_db: (list of data.frames) object containing the ADaM datasets
arm_var: (string) variable used for column splitting
lbl_overall: (string) label used for overall column, if set to NULL the overall column is omitted
analysis_abn_var: (string) column describing anomaly magnitude
baseline_abn_var: (string) column describing anomaly at baseline.
row_split_var: (character) additional row split variables.
page_var: (string) variable name prior to which the row split is by page.
...: not used.
tlg: (TableTree, Listing or ggplot) object typically produced by a main function.

Value

the main function returns an rtables object.

the preprocessing function returns a list of data.frame.

the postprocessing function returns an rtables object or an ElementaryTable (null report).

Details

Only count LOW or HIGH values.
Lab test results with missing analysis_abn_var values are excluded.
Split columns by arm, typically ACTARM.
Does not include a total column by default.

Functions

lbt04_main(): Main TLG function
lbt04_pre(): Preprocessing
lbt04_post(): Postprocessing

Note

adam_db object must contain an adlb table with columns "PARCAT1", "PARCAT2", "PARAM", "ANRIND", and column specified by arm_var.

Examples

run(lbt04, syn_data)
#>   Laboratory Test                           A: Drug X    B: Placebo    C: Combination
#>       Direction of Abnormality               (N=15)        (N=15)          (N=15)    
#>   ———————————————————————————————————————————————————————————————————————————————————
#>   CHEMISTRY                                                                          
#>     Alanine Aminotransferase Measurement                                             
#>       Low                                  1/7 (14.3%)   1/3 (33.3%)        0/8      
#>       High                                 2/7 (28.6%)       0/2        1/9 (11.1%)  
#>     C-Reactive Protein Measurement                                                   
#>       Low                                      0/8           0/2        2/7 (28.6%)  
#>       High                                     0/8           0/3            0/7      
#>     Immunoglobulin A Measurement                                                     
#>       Low                                  2/5 (40.0%)   1/8 (12.5%)    1/6 (16.7%)  
#>       High                                 2/5 (40.0%)   1/9 (11.1%)        0/6      
#>   COAGULATION                                                                        
#>     Alanine Aminotransferase Measurement                                             
#>       Low                                      0/5       1/5 (20.0%)        0/5      
#>       High                                     0/6       1/6 (16.7%)    1/5 (20.0%)  
#>     C-Reactive Protein Measurement                                                   
#>       Low                                  1/6 (16.7%)       0/5        1/4 (25.0%)  
#>       High                                 1/5 (20.0%)   1/6 (16.7%)        0/3      
#>     Immunoglobulin A Measurement                                                     
#>       Low                                      0/7           0/9            0/7      
#>       High                                 1/7 (14.3%)      0/10            0/6      
#>   HEMATOLOGY                                                                         
#>     Alanine Aminotransferase Measurement                                             
#>       Low                                  1/5 (20.0%)   1/5 (20.0%)        0/4      
#>       High                                     0/5           0/4            0/4      
#>     C-Reactive Protein Measurement                                                   
#>       Low                                  1/4 (25.0%)       0/2        3/9 (33.3%)  
#>       High                                     0/4           0/5            0/9      
#>     Immunoglobulin A Measurement                                                     
#>       Low                                      0/2           0/3        2/8 (25.0%)  
#>       High                                     0/4       1/4 (25.0%)        0/7