LBT01 Table 1 (Default) Laboratory Test Results and Change from Baseline by Visit.
lbt01_1.RdThe LBT01 table provides an
overview of the analysis values and its change from baseline of each respective arm over the course of the trial.
Usage
lbt01_1_main(
adam_db,
arm_var = "ACTARM",
summaryvars = list(`Value at Visit` = "AVAL", `Change from \nBaseline` = "CHG"),
visitvar = "AVISIT",
precision = list(),
default_precision = 2,
deco = std_deco("LBT01"),
...
)
lbt01_1_lyt(
arm_var,
summaryvars,
summaryvars_lbls,
visitvar,
lbl_avisit,
lbl_param,
deco,
precision,
default_precision
)
lbt01_1_pre(adam_db, ...)
lbt01_1_post(tlg, prune_0 = TRUE, ...)
lbt01_1Arguments
- adam_db
(
dm) object containing theADaMdatasets- arm_var
(
string) variable used for column splitting- summaryvars
(
character) the variables to be analyzed. For this table,AVALandCHGby default.- visitvar
(
string) typically one of"AVISIT"(Default) or"ATPTN"depending on the type of time point to be displayed.- precision
(named
listofinteger) where names are values found in thePARAMCDcolumn and the the values indicate the number of digits that should be represented formin,maxandmedian.Meanandsdare represented with one more decimal of precision.- default_precision
(
integer) the default number of digits.- deco
(
character) decoration withtitle,subtitlesandmain_footercontent- ...
not used.
- summaryvars_lbls
(
character) the label of the variables to be analyzed.- lbl_avisit
(
string) label of thevisitvarvariable.- lbl_param
(
string) label of thePARAMvariable.- tlg
(
TableTree,Listingorggplot) object typically produced by amainfunction.- prune_0
(
flag) remove 0 count rows
Details
The
Analysis Valuecolumn, displays the number of patients, the mean, standard deviation, median and range of the analysis value for each visit.The
Change from Baselinecolumn, displays the number of patient and the mean, standard deviation, median and range of changes relative to the baseline.Remove zero-count rows unless overridden with
prune_0 = FALSE.Split columns by arm, typically
ACTARM.Does not include a total column by default.
Sorted based on factor level; first by
PARAMlabels in alphabetic order then by chronological time point given byAVISIT. Re-level to customize order.
Functions
lbt01_1_main(): Main TLG functionlbt01_1_lyt(): Layoutlbt01_1_pre(): Preprocessinglbt01_1_post(): Postprocessing
Examples
run(lbt01_1, syn_data, precision = list(
"ALT" = 0,
"CRP" = 1
))
#> Parameter
#> Analysis Visit A: Drug X B: Placebo C: Combination
#> Change from Change from Change from
#> Value at Visit Baseline Value at Visit Baseline Value at Visit Baseline
#> ——————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
#> Alanine Aminotransferase Measurement
#> BASELINE
#> n 134 134 132
#> Mean (SD) 19.786 (4.161) 20.153 (4.171) 20.451 (3.911)
#> Median 19.786 20.077 20.387
#> Min - Max 6.99 - 30.43 8.11 - 34.56 8.82 - 28.72
#> WEEK 1 DAY 8
#> n 134 134 134 134 132 132
#> Mean (SD) 19.301 (3.981) -0.485 (5.850) 20.221 (3.974) 0.068 (6.036) 20.553 (3.895) 0.102 (5.461)
#> Median 19.209 -0.511 20.090 -0.725 20.402 0.025
#> Min - Max 8.86 - 27.32 -12.52 - 19.70 5.84 - 28.75 -12.29 - 17.41 9.87 - 30.70 -13.69 - 15.54
#> WEEK 2 DAY 15
#> n 134 134 134 134 132 132
#> Mean (SD) 19.704 (4.233) -0.082 (6.003) 20.123 (4.265) -0.030 (6.263) 19.247 (3.592) -1.204 (5.485)
#> Median 19.168 0.038 19.986 -0.371 19.608 -0.482
#> Min - Max 7.17 - 30.53 -13.15 - 17.17 7.19 - 30.54 -18.37 - 14.39 8.11 - 26.68 -14.28 - 15.65
#> WEEK 3 DAY 22
#> n 134 134 134 134 132 132
#> Mean (SD) 20.130 (3.757) 0.344 (5.761) 19.837 (3.871) -0.316 (5.604) 19.428 (3.944) -1.023 (5.550)
#> Median 20.044 0.451 19.873 -0.178 18.838 -1.065
#> Min - Max 11.52 - 29.49 -16.04 - 16.26 11.86 - 28.24 -18.52 - 15.00 10.20 - 28.49 -12.33 - 11.10
#> WEEK 4 DAY 29
#> n 134 134 134 134 132 132
#> Mean (SD) 20.351 (4.583) 0.565 (6.506) 19.632 (4.346) -0.521 (6.293) 19.823 (3.995) -0.627 (5.311)
#> Median 19.763 0.353 19.151 -1.186 19.884 -0.646
#> Min - Max 9.88 - 34.50 -17.00 - 18.79 11.49 - 31.98 -16.58 - 17.23 7.76 - 29.31 -12.13 - 15.30
#> WEEK 5 DAY 36
#> n 134 134 134 134 132 132
#> Mean (SD) 20.418 (3.925) 0.632 (6.053) 19.859 (4.223) -0.294 (6.315) 19.990 (4.169) -0.460 (5.570)
#> Median 20.718 0.926 20.113 0.728 20.503 -0.990
#> Min - Max 10.95 - 30.17 -16.03 - 16.09 10.32 - 29.06 -19.04 - 12.64 7.41 - 27.78 -15.62 - 16.61
#> C-Reactive Protein Measurement
#> BASELINE
#> n 134 134 132
#> Mean (SD) 0.974 (0.236) 1.002 (0.197) 1.005 (0.210)
#> Median 0.989 1.003 0.996
#> Min - Max 0.47 - 1.63 0.50 - 1.58 0.51 - 1.56
#> WEEK 1 DAY 8
#> n 134 134 134 134 132 132
#> Mean (SD) 1.047 (0.202) 0.073 (0.312) 1.007 (0.220) 0.005 (0.289) 1.006 (0.234) 0.001 (0.327)
#> Median 1.031 0.074 1.031 0.015 1.017 -0.008
#> Min - Max 0.46 - 1.57 -0.71 - 1.03 0.42 - 1.43 -0.78 - 0.93 0.44 - 1.53 -0.80 - 0.75
#> WEEK 2 DAY 15
#> n 134 134 134 134 132 132
#> Mean (SD) 0.994 (0.207) 0.020 (0.314) 1.022 (0.186) 0.020 (0.267) 0.978 (0.206) -0.027 (0.278)
#> Median 1.011 0.012 1.038 0.021 0.967 -0.035
#> Min - Max 0.48 - 1.48 -0.85 - 0.76 0.52 - 1.44 -0.55 - 0.68 0.27 - 1.51 -0.76 - 0.50
#> WEEK 3 DAY 22
#> n 134 134 134 134 132 132
#> Mean (SD) 1.002 (0.208) 0.028 (0.309) 0.982 (0.188) -0.020 (0.266) 0.995 (0.191) -0.010 (0.301)
#> Median 0.998 0.078 0.969 0.004 0.987 -0.029
#> Min - Max 0.42 - 1.48 -0.92 - 0.79 0.52 - 1.44 -0.77 - 0.75 0.50 - 1.57 -0.72 - 0.86
#> WEEK 4 DAY 29
#> n 134 134 134 134 132 132
#> Mean (SD) 1.040 (0.203) 0.067 (0.306) 0.987 (0.205) -0.015 (0.278) 0.994 (0.190) -0.011 (0.289)
#> Median 1.056 0.079 0.970 -0.032 1.004 0.018
#> Min - Max 0.54 - 1.53 -0.78 - 1.04 0.43 - 1.43 -0.62 - 0.59 0.55 - 1.46 -0.82 - 0.82
#> WEEK 5 DAY 36
#> n 134 134 134 134 132 132
#> Mean (SD) 0.993 (0.219) 0.019 (0.334) 1.021 (0.190) 0.019 (0.282) 0.976 (0.191) -0.029 (0.290)
#> Median 0.981 -0.006 1.006 0.011 0.980 -0.037
#> Min - Max 0.40 - 1.49 -1.00 - 0.84 0.58 - 1.51 -0.64 - 0.83 0.55 - 1.59 -0.84 - 0.79
#> Immunoglobulin A Measurement
#> BASELINE
#> n 134 134 132
#> Mean (SD) 1.996 (0.372) 1.987 (0.415) 2.015 (0.453)
#> Median 1.934 1.964 1.987
#> Min - Max 1.19 - 2.80 0.79 - 3.07 0.80 - 3.00
#> WEEK 1 DAY 8
#> n 134 134 134 134 132 132
#> Mean (SD) 1.970 (0.404) -0.026 (0.534) 2.056 (0.409) 0.069 (0.562) 2.038 (0.421) 0.022 (0.645)
#> Median 1.989 -0.007 2.026 0.077 2.055 0.023
#> Min - Max 0.97 - 2.97 -1.42 - 1.08 1.06 - 3.23 -1.27 - 1.78 0.81 - 3.05 -1.49 - 1.55
#> WEEK 2 DAY 15
#> n 134 134 134 134 132 132
#> Mean (SD) 2.036 (0.393) 0.040 (0.576) 1.994 (0.417) 0.007 (0.583) 1.969 (0.374) -0.046 (0.602)
#> Median 1.989 0.068 2.034 0.047 1.978 -0.010
#> Min - Max 1.17 - 3.09 -1.29 - 1.61 0.89 - 2.99 -1.48 - 1.38 0.97 - 2.75 -1.64 - 1.45
#> WEEK 3 DAY 22
#> n 134 134 134 134 132 132
#> Mean (SD) 1.974 (0.402) -0.022 (0.519) 1.999 (0.396) 0.012 (0.577) 2.048 (0.391) 0.033 (0.602)
#> Median 1.964 0.023 1.957 0.039 2.056 0.013
#> Min - Max 0.71 - 2.81 -1.44 - 1.21 0.75 - 2.89 -1.60 - 1.21 0.99 - 2.99 -1.81 - 1.23
#> WEEK 4 DAY 29
#> n 134 134 134 134 132 132
#> Mean (SD) 1.962 (0.384) -0.035 (0.543) 1.955 (0.381) -0.032 (0.551) 1.979 (0.420) -0.037 (0.622)
#> Median 2.025 -0.001 1.945 0.028 1.993 -0.068
#> Min - Max 0.80 - 2.73 -1.53 - 1.33 1.07 - 2.81 -1.38 - 1.09 0.99 - 2.95 -1.35 - 1.59
#> WEEK 5 DAY 36
#> n 134 134 134 134 132 132
#> Mean (SD) 1.983 (0.384) -0.013 (0.505) 2.018 (0.433) 0.031 (0.635) 1.965 (0.427) -0.050 (0.609)
#> Median 1.961 -0.012 1.987 0.071 2.009 0.034
#> Min - Max 1.04 - 3.07 -1.69 - 1.28 0.92 - 3.35 -1.38 - 1.64 0.62 - 2.88 -1.60 - 1.32