Average OS Hazard Ratio from Constant Transition Hazards

Average OS Hazard Ratio from Constant Transition Hazards

Usage

avgHRExpOS(transitionByArm, alpha = 0.5, upper = Inf)

Arguments

transitionByArm

(list)
transition parameters for each treatment group. See exponential_transition(), piecewise_exponential() and weibull_transition() for details.

alpha

(number)
assigns weights to time points, where values higher than 0.5 assign greater weight to earlier times and values lower than 0.5 assign greater weight to later times.

upper

(number)
upper (time) limit of integration.

Value

This returns the value of the average hazard ratio.

Examples

transitionTrt <- exponential_transition(h01 = 0.18, h02 = 0.06, h12 = 0.17)
transitionCtl <- exponential_transition(h01 = 0.23, h02 = 0.07, h12 = 0.19)
transitionList <- list(transitionCtl, transitionTrt)
avgHRExpOS(transitionByArm = transitionList, alpha = 0.5, upper = 100)
#> [1] 0.8319853