EGT03 Shift Table of ECG Interval Data - Baseline versus Minimum or Maximum Post-Baseline.

The EGT03 Table entries provide the number of patients by baseline assessment and minimum or maximum post-baseline assessment. Percentages are based on the total number of patients in a treatment group. Baseline is the patient's last observation prior to initiation of study drug.

Usage

egt03_main(
  adam_db,
  arm_var = "ACTARMCD",
  summaryvar = "BNRIND",
  splitvar = "ANRIND",
  visitvar = "AVISIT",
  page_var = "PARAMCD",
  ...
)

egt03_pre(adam_db, ...)

egt03_post(tlg, prune_0 = FALSE, ...)

egt03

Format

An object of class chevron_t of length 1.

Arguments

adam_db: (list of data.frames) object containing the ADaM datasets
arm_var: (character) the arm variables used for row split, typically "ACTARMCD".
summaryvar: (character) variables to be analyzed, typically "BNRIND". Labels of the corresponding columns are used as subtitles.
splitvar: (character) variables to be analyzed, typically "ANRIND". Labels of the corresponding columns are used as subtitles.
visitvar: (string) typically "AVISIT" or user-defined visit incorporating "ATPT".
page_var: (string) variable name prior to which the row split is by page.
...: not used.
tlg: (TableTree, Listing or ggplot) object typically produced by a main function.
prune_0: (flag) remove 0 count rows

Value

the main function returns an rtables object.

the preprocessing function returns a list of data.frame.

the postprocessing function returns an rtables object or an ElementaryTable (null report).

Details

ADEG data are subsetted to contain only "POST-BASELINE MINIMUM"/"POST-BASELINE MAXIMUM" visit according to the preprocessing.
Percentages are based on the total number of patients in a treatment group.
Split columns by Analysis Reference Range Indicator, typically ANRIND.
Does not include a total column by default.
Sorted based on factor level.

Functions

egt03_main(): Main TLG function
egt03_pre(): Preprocessing
egt03_post(): Postprocessing

Note

adam_db object must contain an adeg table with a "ACTARMCD" column as well as columns specified in summaryvar and splitvar.

Examples

library(dunlin)

proc_data <- log_filter(syn_data, PARAMCD == "HR", "adeg")
run(egt03, proc_data)
#>   Actual Arm Code                            Minimum Post-Baseline Assessment     
#>     Baseline Reference Range Indicator       LOW         NORMAL     HIGH   Missing
#>   ————————————————————————————————————————————————————————————————————————————————
#>   Heart Rate                                                                      
#>     ARM A (N=134)                                                                 
#>       LOW                                 1 (0.7%)      5 (3.7%)     0        0   
#>       NORMAL                             36 (26.9%)    85 (63.4%)    0        0   
#>       HIGH                                3 (2.2%)      4 (3.0%)     0        0   
#>       Missing                                 0            0         0        0   
#>     ARM B (N=134)                                                                 
#>       LOW                                 1 (0.7%)      9 (6.7%)     0        0   
#>       NORMAL                             41 (30.6%)    78 (58.2%)    0        0   
#>       HIGH                                1 (0.7%)      4 (3.0%)     0        0   
#>       Missing                                 0            0         0        0   
#>     ARM C (N=132)                                                                 
#>       LOW                                 4 (3.0%)     11 (8.3%)     0        0   
#>       NORMAL                             32 (24.2%)    75 (56.8%)    0        0   
#>       HIGH                                1 (0.8%)      9 (6.8%)     0        0   
#>       Missing                                 0            0         0        0