VST01 Table 1 (Default) Vital Sign Results and change from Baseline By Visit Table 1.
vst01_1.RdThe VST01 table provides an
overview of the Vital Sign values and its change from baseline of each respective arm
over the course of the trial.
Usage
vst01_1_main(
adam_db,
arm_var = "ACTARM",
summaryvars = list(`Value at Visit` = "AVAL", `Change from \nBaseline` = "CHG"),
visitvar = "AVISIT",
deco = std_deco("VST01"),
...
)
vst01_1_lyt(
arm_var,
summaryvars,
summaryvars_lbls,
visitvar,
lbl_avisit,
lbl_param,
deco
)
vst01_1_pre(adam_db, ...)
vst01_1_post(tlg, prune_0 = TRUE, ...)
vst01_1Arguments
- adam_db
(
dm) object containing theADaMdatasets- arm_var
(
string) variable used for column splitting- summaryvars
(
character) the variables to be analyzed. For this table,AVALandCHGby default.- visitvar
(
string) typically one of"AVISIT"(Default) or"ATPTN"depending on the type of time point to be displayed.- deco
(
character) decoration withtitle,subtitlesandmain_footercontent- ...
not used.
- summaryvars_lbls
(
character) the label of the variables to be analyzed.- lbl_avisit
(
string) label of thevisitvarvariable.- lbl_param
(
string) label of thePARAMvariable.- tlg
(
TableTree,Listingorggplot) object typically produced by amainfunction.- prune_0
(
flag) remove 0 count rows
Details
The
Analysis Valuecolumn, displays the number of patients, the mean, standard deviation, median and range of the analysis value for each visit.The
Change from Baselinecolumn, displays the number of patient and the mean, standard deviation, median and range of changes relative to the baseline.Remove zero-count rows unless overridden with
prune_0 = FALSE.Split columns by arm, typically
ACTARM.Does not include a total column by default.
Sorted based on factor level; first by
PARAMlabels in alphabetic order then by chronological time point given byAVISIT. Re-level to customize order
Functions
vst01_1_main(): Main TLG functionvst01_1_lyt(): Layoutvst01_1_pre(): Preprocessingvst01_1_post(): Postprocessing
Examples
run(vst01_1, syn_data)
#> Parameter A: Drug X B: Placebo C: Combination
#> Analysis Visit Change from Change from Change from
#> Value at Visit Baseline Value at Visit Baseline Value at Visit Baseline
#> ————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
#> Diastolic Blood Pressure
#> SCREENING
#> n 134 0 134 0 132 0
#> Mean (SD) 50.0 (7.2) NA 50.8 (8.4) NA 50.2 (7.6) NA
#> Median 49.7 NA 50.1 NA 49.6 NA
#> Min - Max 31.7 - 71.2 NA 29.3 - 69.2 NA 26.9 - 70.0 NA
#> BASELINE
#> n 134 134 134 134 132 132
#> Mean (SD) 48.6 (8.0) 0.0 (0.0) 50.4 (7.9) 0.0 (0.0) 51.1 (7.8) 0.0 (0.0)
#> Median 48.4 0.0 50.2 0.0 50.8 0.0
#> Min - Max 27.7 - 64.6 0.0 - 0.0 21.7 - 67.5 0.0 - 0.0 29.7 - 71.4 0.0 - 0.0
#> WEEK 1 DAY 8
#> n 134 134 134 134 132 132
#> Mean (SD) 50.3 (7.5) 1.7 (10.8) 49.7 (7.7) -0.8 (10.9) 48.9 (7.9) -2.3 (10.4)
#> Median 50.1 0.6 49.7 -1.1 47.7 -2.2
#> Min - Max 33.0 - 69.0 -20.4 - 29.9 33.7 - 66.5 -25.8 - 28.4 30.4 - 67.0 -22.1 - 22.4
#> WEEK 2 DAY 15
#> n 134 134 134 134 132 132
#> Mean (SD) 50.8 (7.8) 2.2 (11.8) 49.7 (8.4) -0.7 (12.4) 50.0 (8.3) -1.1 (11.6)
#> Median 51.4 3.1 50.2 -0.7 51.0 -2.3
#> Min - Max 31.9 - 70.3 -23.9 - 39.2 30.6 - 68.1 -28.4 - 37.0 24.8 - 65.6 -29.2 - 30.7
#> WEEK 3 DAY 22
#> n 134 134 134 134 132 132
#> Mean (SD) 50.7 (7.8) 2.1 (10.9) 49.1 (7.9) -1.3 (11.1) 49.9 (7.7) -1.2 (10.9)
#> Median 50.2 2.6 49.5 -2.3 50.0 -0.6
#> Min - Max 29.1 - 74.9 -25.8 - 30.7 24.5 - 67.1 -28.1 - 33.9 31.5 - 68.5 -29.7 - 27.0
#> WEEK 4 DAY 29
#> n 134 134 134 134 132 132
#> Mean (SD) 50.1 (8.1) 1.5 (10.9) 49.6 (7.1) -0.8 (10.6) 49.7 (8.0) -1.4 (11.0)
#> Median 49.3 1.2 49.2 -0.8 49.8 -0.2
#> Min - Max 29.4 - 71.4 -30.9 - 24.8 32.7 - 67.0 -33.2 - 35.9 28.7 - 68.4 -35.5 - 28.4
#> WEEK 5 DAY 36
#> n 134 134 134 134 132 132
#> Mean (SD) 50.6 (7.5) 2.0 (11.2) 48.4 (8.0) -2.1 (11.7) 49.1 (7.6) -2.0 (10.7)
#> Median 49.4 1.6 47.7 -2.9 49.2 -2.2
#> Min - Max 35.1 - 72.2 -25.2 - 31.5 30.4 - 70.6 -31.2 - 29.2 30.6 - 72.9 -30.5 - 34.6
#> Pulse Rate
#> SCREENING
#> n 134 0 134 0 132 0
#> Mean (SD) 49.6 (9.0) NA 49.4 (8.4) NA 49.3 (8.6) NA
#> Median 49.9 NA 48.9 NA 48.6 NA
#> Min - Max 25.9 - 68.8 NA 30.5 - 80.5 NA 26.5 - 67.5 NA
#> BASELINE
#> n 134 134 134 134 132 132
#> Mean (SD) 51.9 (8.1) 0.0 (0.0) 50.3 (8.8) 0.0 (0.0) 50.3 (9.4) 0.0 (0.0)
#> Median 51.2 0.0 51.2 0.0 50.7 0.0
#> Min - Max 28.5 - 72.9 0.0 - 0.0 26.9 - 67.3 0.0 - 0.0 27.8 - 71.2 0.0 - 0.0
#> WEEK 1 DAY 8
#> n 134 134 134 134 132 132
#> Mean (SD) 50.1 (8.3) -1.8 (11.6) 49.3 (7.5) -1.0 (11.6) 49.8 (7.7) -0.5 (12.6)
#> Median 49.9 -2.7 48.8 -2.2 49.5 -1.5
#> Min - Max 26.7 - 69.4 -26.4 - 29.6 30.7 - 67.8 -29.5 - 32.1 30.1 - 72.9 -25.1 - 33.3
#> WEEK 2 DAY 15
#> n 134 134 134 134 132 132
#> Mean (SD) 49.7 (8.8) -2.2 (12.4) 50.8 (7.6) 0.6 (11.8) 49.1 (7.7) -1.2 (11.3)
#> Median 49.2 -3.0 50.3 0.1 49.2 -1.1
#> Min - Max 26.0 - 69.6 -37.6 - 26.4 33.3 - 70.3 -28.9 - 37.7 32.2 - 73.6 -33.7 - 26.3
#> WEEK 3 DAY 22
#> n 134 134 134 134 132 132
#> Mean (SD) 50.5 (7.4) -1.4 (11.1) 49.9 (7.8) -0.4 (11.0) 49.8 (7.2) -0.5 (12.1)
#> Median 50.6 -1.1 49.4 -0.8 49.6 -2.3
#> Min - Max 27.7 - 73.0 -30.0 - 26.5 27.8 - 71.0 -26.5 - 33.4 27.9 - 67.5 -28.7 - 28.0
#> WEEK 4 DAY 29
#> n 134 134 134 134 132 132
#> Mean (SD) 49.0 (8.3) -2.9 (11.1) 50.0 (8.4) -0.3 (12.0) 51.0 (7.7) 0.7 (11.6)
#> Median 48.8 -3.0 49.9 -0.4 51.4 0.7
#> Min - Max 32.3 - 78.4 -28.4 - 30.4 30.4 - 79.8 -29.1 - 28.3 31.4 - 70.3 -30.6 - 25.1
#> WEEK 5 DAY 36
#> n 134 134 134 134 132 132
#> Mean (SD) 48.4 (8.5) -3.5 (11.6) 50.3 (7.2) 0.0 (11.2) 49.7 (7.6) -0.5 (12.4)
#> Median 47.7 -4.0 50.3 -1.5 49.1 -2.7
#> Min - Max 25.0 - 75.7 -41.3 - 31.5 29.4 - 67.7 -24.9 - 27.3 35.3 - 73.7 -24.6 - 34.0
#> Respiratory Rate
#> SCREENING
#> n 134 0 134 0 132 0
#> Mean (SD) 49.2 (8.2) NA 50.3 (8.3) NA 49.6 (8.4) NA
#> Median 49.3 NA 49.9 NA 50.1 NA
#> Min - Max 26.0 - 74.4 NA 31.4 - 69.2 NA 24.3 - 67.9 NA
#> BASELINE
#> n 134 134 134 134 132 132
#> Mean (SD) 49.4 (8.1) 0.0 (0.0) 51.1 (8.2) 0.0 (0.0) 50.8 (8.4) 0.0 (0.0)
#> Median 49.8 0.0 50.5 0.0 51.1 0.0
#> Min - Max 29.3 - 69.3 0.0 - 0.0 31.2 - 74.5 0.0 - 0.0 26.2 - 71.0 0.0 - 0.0
#> WEEK 1 DAY 8
#> n 134 134 134 134 132 132
#> Mean (SD) 49.5 (8.0) 0.1 (11.6) 50.0 (7.9) -1.1 (11.5) 51.0 (7.8) 0.2 (11.1)
#> Median 49.3 0.2 49.1 -1.6 51.1 0.4
#> Min - Max 24.1 - 66.1 -31.6 - 32.1 25.0 - 67.7 -29.1 - 30.9 29.9 - 69.8 -23.6 - 27.7
#> WEEK 2 DAY 15
#> n 134 134 134 134 132 132
#> Mean (SD) 49.7 (7.7) 0.3 (9.7) 50.4 (8.7) -0.8 (12.1) 49.3 (8.5) -1.4 (12.0)
#> Median 49.2 1.4 49.7 -1.6 50.2 -1.6
#> Min - Max 30.8 - 71.3 -24.9 - 27.6 28.5 - 77.0 -29.0 - 28.9 22.4 - 67.6 -43.8 - 27.0
#> WEEK 3 DAY 22
#> n 134 134 134 134 132 132
#> Mean (SD) 50.6 (8.2) 1.2 (11.7) 50.2 (6.9) -1.0 (10.1) 49.1 (7.3) -1.6 (11.1)
#> Median 50.5 0.7 49.7 -0.7 49.6 -0.9
#> Min - Max 33.2 - 70.8 -33.5 - 33.3 32.3 - 67.8 -29.6 - 22.2 27.4 - 63.3 -25.4 - 33.6
#> WEEK 4 DAY 29
#> n 134 134 134 134 132 132
#> Mean (SD) 49.4 (7.7) 0.0 (10.9) 49.9 (7.8) -1.2 (11.0) 50.8 (7.8) 0.1 (11.1)
#> Median 48.9 -1.4 48.9 -2.4 50.4 -0.6
#> Min - Max 25.9 - 69.7 -25.9 - 40.3 33.7 - 68.5 -25.0 - 29.2 31.9 - 72.0 -27.6 - 31.1
#> WEEK 5 DAY 36
#> n 134 134 134 134 132 132
#> Mean (SD) 49.9 (7.7) 0.5 (11.5) 50.6 (8.2) -0.5 (12.0) 49.9 (7.9) -0.8 (10.6)
#> Median 49.8 -0.2 50.3 -0.6 49.6 -1.7
#> Min - Max 34.3 - 70.7 -30.3 - 37.2 28.4 - 69.8 -29.4 - 23.8 29.8 - 68.4 -21.3 - 22.3
#> Systolic Blood Pressure
#> SCREENING
#> n 134 0 134 0 132 0
#> Mean (SD) 49.6 (8.3) NA 50.3 (8.3) NA 50.9 (7.8) NA
#> Median 49.6 NA 50.2 NA 50.8 NA
#> Min - Max 24.0 - 70.9 NA 26.2 - 79.1 NA 27.6 - 67.4 NA
#> BASELINE
#> n 134 134 134 134 132 132
#> Mean (SD) 49.4 (8.5) 0.0 (0.0) 50.2 (8.5) 0.0 (0.0) 48.5 (7.2) 0.0 (0.0)
#> Median 48.3 0.0 50.0 0.0 49.2 0.0
#> Min - Max 24.3 - 71.1 0.0 - 0.0 24.4 - 71.1 0.0 - 0.0 26.2 - 63.4 0.0 - 0.0
#> WEEK 1 DAY 8
#> n 134 134 134 134 132 132
#> Mean (SD) 50.7 (9.2) 1.3 (12.8) 49.3 (8.7) -1.0 (11.2) 49.6 (8.0) 1.2 (10.2)
#> Median 49.5 0.1 48.3 -1.7 49.8 0.1
#> Min - Max 29.8 - 79.0 -29.5 - 37.6 33.0 - 74.0 -27.6 - 24.8 25.5 - 68.6 -22.8 - 31.3
#> WEEK 2 DAY 15
#> n 134 134 134 134 132 132
#> Mean (SD) 49.4 (8.5) -0.0 (11.9) 49.4 (7.0) -0.9 (11.0) 49.3 (7.7) 0.8 (9.7)
#> Median 49.5 -0.2 49.4 -0.9 48.3 -0.2
#> Min - Max 24.2 - 65.4 -39.1 - 32.7 27.6 - 69.2 -37.1 - 33.9 29.4 - 74.7 -24.9 - 29.0
#> WEEK 3 DAY 22
#> n 134 134 134 134 132 132
#> Mean (SD) 49.7 (7.8) 0.3 (11.4) 49.0 (7.8) -1.2 (12.1) 50.5 (8.3) 2.0 (11.1)
#> Median 50.1 1.5 48.8 -1.2 51.7 2.0
#> Min - Max 31.3 - 70.3 -27.5 - 27.1 15.6 - 66.2 -35.6 - 36.4 29.6 - 69.4 -29.7 - 30.6
#> WEEK 4 DAY 29
#> n 134 134 134 134 132 132
#> Mean (SD) 49.4 (7.6) 0.0 (11.5) 49.4 (8.6) -0.8 (12.6) 50.7 (7.4) 2.2 (10.5)
#> Median 49.8 0.6 49.9 -1.3 50.8 3.0
#> Min - Max 22.9 - 69.6 -32.3 - 28.5 22.1 - 72.1 -29.7 - 38.1 29.7 - 65.1 -28.8 - 34.1
#> WEEK 5 DAY 36
#> n 134 134 134 134 132 132
#> Mean (SD) 49.4 (7.9) -0.0 (11.9) 50.2 (8.7) -0.0 (11.8) 50.4 (8.2) 1.9 (10.5)
#> Median 49.6 0.7 49.9 0.2 50.8 2.4
#> Min - Max 26.1 - 69.7 -39.2 - 33.9 27.9 - 74.2 -27.7 - 36.2 34.3 - 74.5 -23.7 - 32.4
#> Temperature
#> SCREENING
#> n 134 0 134 0 132 0
#> Mean (SD) 48.9 (9.4) NA 50.1 (7.9) NA 50.2 (8.4) NA
#> Median 49.6 NA 50.1 NA 49.8 NA
#> Min - Max 29.0 - 75.2 NA 29.9 - 73.4 NA 30.5 - 72.3 NA
#> BASELINE
#> n 134 134 134 134 132 132
#> Mean (SD) 49.7 (8.3) 0.0 (0.0) 50.9 (7.4) 0.0 (0.0) 49.1 (8.2) 0.0 (0.0)
#> Median 50.4 0.0 51.5 0.0 48.7 0.0
#> Min - Max 29.0 - 69.1 0.0 - 0.0 30.7 - 67.7 0.0 - 0.0 20.6 - 70.5 0.0 - 0.0
#> WEEK 1 DAY 8
#> n 134 134 134 134 132 132
#> Mean (SD) 51.6 (8.1) 1.9 (11.8) 49.5 (8.2) -1.4 (9.9) 49.8 (7.6) 0.6 (11.2)
#> Median 52.3 2.3 48.8 -1.1 50.2 0.9
#> Min - Max 31.5 - 71.2 -28.0 - 33.2 27.1 - 67.3 -28.1 - 26.6 32.1 - 68.5 -28.0 - 29.4
#> WEEK 2 DAY 15
#> n 134 134 134 134 132 132
#> Mean (SD) 50.2 (7.5) 0.5 (11.0) 49.5 (7.0) -1.3 (10.2) 51.8 (8.1) 2.6 (11.8)
#> Median 50.7 -0.7 49.7 -0.7 51.6 2.8
#> Min - Max 35.1 - 67.7 -33.9 - 25.4 32.3 - 73.2 -29.7 - 29.0 30.1 - 73.3 -24.9 - 32.8
#> WEEK 3 DAY 22
#> n 134 134 134 134 132 132
#> Mean (SD) 50.1 (8.2) 0.3 (11.1) 49.9 (8.0) -1.0 (10.9) 49.7 (8.2) 0.6 (11.1)
#> Median 49.5 1.1 49.6 -1.1 49.2 0.5
#> Min - Max 29.0 - 68.7 -29.3 - 24.1 32.7 - 70.3 -28.3 - 21.6 35.2 - 75.2 -27.3 - 32.0
#> WEEK 4 DAY 29
#> n 134 134 134 134 132 132
#> Mean (SD) 50.7 (7.7) 0.9 (11.8) 49.8 (8.5) -1.1 (11.8) 49.9 (7.5) 0.8 (11.5)
#> Median 50.7 1.4 49.8 -1.7 49.8 0.1
#> Min - Max 29.7 - 70.8 -25.9 - 29.2 24.4 - 68.9 -28.2 - 37.3 28.4 - 68.6 -25.8 - 32.5
#> WEEK 5 DAY 36
#> n 134 134 134 134 132 132
#> Mean (SD) 50.3 (8.3) 0.6 (12.3) 50.5 (8.1) -0.4 (11.7) 50.1 (7.3) 0.9 (10.8)
#> Median 49.8 -0.5 50.8 -0.3 49.7 0.9
#> Min - Max 33.4 - 75.0 -30.1 - 33.4 34.6 - 78.0 -23.1 - 30.9 31.1 - 73.4 -23.8 - 39.1
#> Weight
#> SCREENING
#> n 134 0 134 0 132 0
#> Mean (SD) 49.9 (7.4) NA 49.7 (8.3) NA 50.3 (9.1) NA
#> Median 48.7 NA 49.3 NA 49.7 NA
#> Min - Max 33.7 - 65.9 NA 25.8 - 71.5 NA 26.0 - 70.0 NA
#> BASELINE
#> n 134 134 134 134 132 132
#> Mean (SD) 50.7 (7.9) 0.0 (0.0) 49.9 (8.3) 0.0 (0.0) 49.4 (7.5) 0.0 (0.0)
#> Median 49.8 0.0 50.7 0.0 49.6 0.0
#> Min - Max 33.3 - 71.9 0.0 - 0.0 27.9 - 69.8 0.0 - 0.0 29.4 - 65.1 0.0 - 0.0
#> WEEK 1 DAY 8
#> n 134 134 134 134 132 132
#> Mean (SD) 49.2 (7.7) -1.5 (11.4) 49.1 (7.6) -0.8 (11.4) 49.6 (8.4) 0.2 (12.1)
#> Median 50.5 -0.2 48.9 -2.7 49.9 -0.5
#> Min - Max 26.0 - 64.5 -42.9 - 21.3 31.5 - 66.1 -25.0 - 23.5 29.7 - 69.1 -31.0 - 32.6
#> WEEK 2 DAY 15
#> n 134 134 134 134 132 132
#> Mean (SD) 50.9 (8.2) 0.2 (11.2) 50.0 (7.8) 0.1 (12.5) 49.7 (7.9) 0.4 (10.8)
#> Median 50.3 2.0 50.2 -0.2 49.8 1.3
#> Min - Max 32.1 - 70.1 -30.0 - 22.8 28.7 - 72.1 -29.2 - 34.6 28.1 - 73.7 -28.0 - 26.6
#> WEEK 3 DAY 22
#> n 134 134 134 134 132 132
#> Mean (SD) 49.0 (8.0) -1.8 (11.4) 49.6 (8.3) -0.3 (12.5) 50.4 (8.1) 1.1 (10.8)
#> Median 48.9 -1.3 48.5 -1.0 50.8 -0.2
#> Min - Max 31.7 - 75.4 -29.7 - 24.9 32.4 - 76.0 -36.8 - 34.4 27.8 - 70.9 -28.9 - 31.7
#> WEEK 4 DAY 29
#> n 134 134 134 134 132 132
#> Mean (SD) 50.1 (8.1) -0.7 (11.2) 49.5 (8.1) -0.4 (10.4) 49.7 (7.5) 0.3 (10.4)
#> Median 50.9 -0.9 49.4 -0.5 49.6 -1.2
#> Min - Max 30.1 - 68.9 -29.5 - 24.3 29.0 - 69.5 -24.9 - 26.3 30.8 - 77.4 -23.4 - 29.9
#> WEEK 5 DAY 36
#> n 134 134 134 134 132 132
#> Mean (SD) 49.0 (8.1) -1.7 (11.5) 51.6 (8.5) 1.7 (11.5) 49.9 (7.4) 0.5 (10.9)
#> Median 49.8 -0.8 51.8 1.2 49.6 -0.2
#> Min - Max 26.4 - 66.7 -34.8 - 29.7 26.3 - 76.6 -24.0 - 29.3 28.7 - 67.9 -36.1 - 31.0