MHT01 Table 1 (Default) Medical History Table 1.

The MHT01 table provides an overview of the subjects medical history by SOC and Preferred Term.

Usage

mht01_1_main(
  adam_db,
  arm_var = "ARM",
  lbl_overall = NULL,
  lbl_mhbodsys = "MedDRA System Organ Class",
  lbl_mhdecod = "MedDRA Preferred Term",
  deco = std_deco("MHT01"),
  ...
)

mht01_1_lyt(arm_var, lbl_overall, lbl_mhbodsys, lbl_mhdecod, deco)

mht01_1_pre(adam_db, ...)

mht01_1_post(tlg, prune_0 = TRUE, ...)

mht01_1

Format

An object of class chevron_t of length 1.

Arguments

adam_db: (dm) object containing the ADaM datasets
arm_var: (string) variable used for column splitting
lbl_overall: (string) label used for overall column, if set to NULL the overall column is omitted
lbl_mhbodsys: (string) text label for MHBODSYS. If NULL, the value of the argument defaults to the label of the corresponding column in the admh table.
lbl_mhdecod: (string) text label for MHDECOD. If NULL, the value of the argument defaults to the label of the corresponding column in the admh table.
deco: (character) decoration with title, subtitles and main_footer content
...: not used.
tlg: (TableTree, Listing or ggplot) object typically produced by a main function.
prune_0: (flag) remove 0 count rows

Details

Numbers represent absolute numbers of patients and fraction of N, or absolute number of event when specified.
Remove zero-count rows unless overridden with prune_0 = FALSE.
Split columns by arm.
Does not include a total column by default.
Order by body system alphabetically and within body system and medical condition by decreasing total number of patients with the specific condition.

Functions

mht01_1_main(): Main TLG function
mht01_1_lyt(): Layout
mht01_1_pre(): Preprocessing
mht01_1_post(): Postprocessing

Note

adam_db object must contain an admh table with columns "MHBODSYS" and "MHDECOD".

Examples

run(mht01_1, syn_data)
#>   MedDRA System Organ Class                                 A: Drug X    B: Placebo    C: Combination
#>     MedDRA Preferred Term                                    (N=134)       (N=134)        (N=132)    
#>   ———————————————————————————————————————————————————————————————————————————————————————————————————
#>   Total number of patients with at least one condition     122 (91.0%)   123 (91.8%)    120 (90.9%)  
#>   Total number of conditions                                   609           622            703      
#>   cl A                                                                                               
#>     Total number of patients with at least one condition   78 (58.2%)    75 (56.0%)      89 (67.4%)  
#>     Total number of conditions                                 132           130            160      
#>     trm A_1/2                                              50 (37.3%)    45 (33.6%)      63 (47.7%)  
#>     trm A_2/2                                              48 (35.8%)    48 (35.8%)      50 (37.9%)  
#>   cl B                                                                                               
#>     Total number of patients with at least one condition   96 (71.6%)    89 (66.4%)      97 (73.5%)  
#>     Total number of conditions                                 185           198            205      
#>     trm B_3/3                                              48 (35.8%)    54 (40.3%)      51 (38.6%)  
#>     trm B_2/3                                              49 (36.6%)    44 (32.8%)      52 (39.4%)  
#>     trm B_1/3                                              47 (35.1%)    49 (36.6%)      43 (32.6%)  
#>   cl C                                                                                               
#>     Total number of patients with at least one condition   67 (50.0%)    75 (56.0%)      79 (59.8%)  
#>     Total number of conditions                                 103           116            129      
#>     trm C_2/2                                              35 (26.1%)    48 (35.8%)      55 (41.7%)  
#>     trm C_1/2                                              43 (32.1%)    46 (34.3%)      43 (32.6%)  
#>   cl D                                                                                               
#>     Total number of patients with at least one condition   96 (71.6%)    90 (67.2%)      98 (74.2%)  
#>     Total number of conditions                                 189           178            209      
#>     trm D_3/3                                              47 (35.1%)    58 (43.3%)      57 (43.2%)  
#>     trm D_1/3                                              50 (37.3%)    42 (31.3%)      51 (38.6%)  
#>     trm D_2/3                                              48 (35.8%)    42 (31.3%)      50 (37.9%)