MHT01 Table 1 (Default) Medical History Table 1.

The MHT01 table provides an overview of the subjects medical history by SOC and Preferred Term.

Usage

mht01_1_main(
  adam_db,
  armvar = .study$planarm,
  lbl_overall = .study$lbl_overall,
  lbl_mhbodsys = "MedDRA System Organ Class",
  lbl_mhdecod = "MedDRA Preferred Term",
  prune_0 = TRUE,
  deco = std_deco("MHT01"),
  .study = list(planarm = "ARM", lbl_overall = NULL)
)

mht01_1_lyt(
  armvar = .study$planarm,
  lbl_overall = .study$lbl_overall,
  lbl_mhbodsys = "MedDRA System Organ Class",
  lbl_mhdecod = "MedDRA preferred Term",
  deco = std_deco("MHT01"),
  .study = list(planarm = "ARM", lbl_overall = NULL)
)

mht01_1_pre(adam_db, ...)

mht01_1

Format

An object of class chevron_tlg of length 1.

Arguments

adam_db: (dm) object containing the ADaM datasets
armvar: (character) variable used for column splitting
lbl_overall: (character) label used for overall column, if set to NULL the overall column is omitted
lbl_mhbodsys: (string) text label for MHBODSYS. If NULL, the value of the argument defaults to the label of the corresponding column in the admh table.
lbl_mhdecod: (string) text label for MHDECOD. If NULL, the value of the argument defaults to the label of the corresponding column in the admh table.
prune_0: (logical) remove 0 count rows
deco: (character) decoration with title, subtitles and main_footer content
.study: (list) with default values for the arguments of the function
...: not used.

Details

Numbers represent absolute numbers of patients and fraction of N, or absolute number of event when specified.
Remove zero-count rows unless overridden with prune_0 = FALSE.
Split columns by arm.
Does not include a total column by default.
Order by body system alphabetically and within body system and medical condition by decreasing total number of patients with the specific condition.

Functions

mht01_1_main(): Main TLG function
mht01_1_lyt(): Layout
mht01_1_pre(): Preprocessing

Examples

run(mht01_1, syn_test_data())
#> MedDRA System Organ Class                                A: Drug X    B: Placebo    C: Combination
#>   MedDRA Preferred Term                                   (N=134)       (N=134)        (N=132)    
#> ——————————————————————————————————————————————————————————————————————————————————————————————————
#> Total number of patients with at least one condition     122 (91%)    123 (91.8%)    120 (90.9%)  
#> Total number of conditions                                  609           622            703      
#> cl A                                                                                              
#>   Total number of patients with at least one condition   78 (58.2%)    75 (56%)       89 (67.4%)  
#>   Total number of conditions                                132           130            160      
#>   trm A_1/2                                              50 (37.3%)   45 (33.6%)      63 (47.7%)  
#>   trm A_2/2                                              48 (35.8%)   48 (35.8%)      50 (37.9%)  
#> cl B                                                                                              
#>   Total number of patients with at least one condition   96 (71.6%)   89 (66.4%)      97 (73.5%)  
#>   Total number of conditions                                185           198            205      
#>   trm B_3/3                                              48 (35.8%)   54 (40.3%)      51 (38.6%)  
#>   trm B_2/3                                              49 (36.6%)   44 (32.8%)      52 (39.4%)  
#>   trm B_1/3                                              47 (35.1%)   49 (36.6%)      43 (32.6%)  
#> cl C                                                                                              
#>   Total number of patients with at least one condition    67 (50%)     75 (56%)       79 (59.8%)  
#>   Total number of conditions                                103           116            129      
#>   trm C_2/2                                              35 (26.1%)   48 (35.8%)      55 (41.7%)  
#>   trm C_1/2                                              43 (32.1%)   46 (34.3%)      43 (32.6%)  
#> cl D                                                                                              
#>   Total number of patients with at least one condition   96 (71.6%)   90 (67.2%)      98 (74.2%)  
#>   Total number of conditions                                189           178            209      
#>   trm D_3/3                                              47 (35.1%)   58 (43.3%)      57 (43.2%)  
#>   trm D_1/3                                              50 (37.3%)   42 (31.3%)      51 (38.6%)  
#>   trm D_2/3                                              48 (35.8%)   42 (31.3%)      50 (37.9%)