DTHT01 Table 1 (Default) Death Table. — dtht01_1

A description of the causes of death optionally with the breakdown of the OTHER category and/or post-study reporting of death.

Usage

dtht01_1_main(
  adam_db,
  armvar = .study$actualarm,
  time_since_last_dose = FALSE,
  other_category = FALSE,
  lbl_overall = .study$lbl_overall,
  prune_0 = TRUE,
  deco = std_deco("DTHT01"),
  .study = list(actualarm = "ACTARM", lbl_overall = NULL)
)

dtht01_1_lyt(
  armvar = .study$actualarm,
  lbl_overall = .study$lbl_overall,
  other_category = TRUE,
  deco = std_deco("DTHT01"),
  .study = list(actualarm = "ACTARM", lbl_overall = NULL)
)

dtht01_1_opt_lyt(
  armvar = .study$actualarm,
  lbl_overall = .study$lbl_overall,
  deco = std_deco("DTHT01"),
  .study = list(actualarm = "ACTARM", lbl_overall = NULL)
)

dtht01_1_pre(adam_db, ...)

dtht01_1

Format

An object of class chevron_tlg of length 1.

Arguments

adam_db: (dm) object containing the ADaM datasets
armvar: (character) variable used for column splitting
time_since_last_dose: (logical) should the time to event information be displayed.
other_category: (logical) should the breakdown of the OTHER category be displayed.
lbl_overall: (character) label used for overall column, if set to NULL the overall column is omitted
prune_0: (logical) remove 0 count rows
deco: (character) decoration with title, subtitles and main_footer content
.study: (list) with default values for the arguments of the function
...: not used.

Details

Numbers represent absolute numbers of subjects and fraction of N, or absolute numbers when specified.
Remove zero-count rows unless overridden with prune_0 = FALSE.
Does not include a total column by default.

Functions

dtht01_1_main(): Main TLG function
dtht01_1_lyt(): Layout
dtht01_1_opt_lyt(): Optional Layout
dtht01_1_pre(): Preprocessing

Examples


db <- syn_test_data()

run(dtht01_1, db)
#>                          A: Drug X    B: Placebo   C: Combination
#>                           (N=134)      (N=134)        (N=132)    
#> —————————————————————————————————————————————————————————————————
#> Total number of deaths   22 (16.4%)   26 (19.4%)     19 (14.4%)  
#> Primary cause of death                                           
#>   n                          22           26             19      
#>   ADVERSE EVENT          6 (27.3%)    12 (46.2%)     7 (36.8%)   
#>   PROGRESSIVE DISEASE    7 (31.8%)    9 (34.6%)      8 (42.1%)   
#>   OTHER                  9 (40.9%)    5 (19.2%)      4 (21.1%)   
run(dtht01_1, db, other_category = TRUE, time_since_last_dose = TRUE)
#>                                                             A: Drug X    B: Placebo   C: Combination
#>                                                              (N=134)      (N=134)        (N=132)    
#> ————————————————————————————————————————————————————————————————————————————————————————————————————
#> Total number of deaths                                      22 (16.4%)   26 (19.4%)     19 (14.4%)  
#> Primary cause of death                                                                              
#>   n                                                             22           26             19      
#>   ADVERSE EVENT                                             6 (27.3%)    12 (46.2%)     7 (36.8%)   
#>   PROGRESSIVE DISEASE                                       7 (31.8%)    9 (34.6%)      8 (42.1%)   
#>   OTHER                                                     9 (40.9%)    5 (19.2%)      4 (21.1%)   
#>         LOST TO FOLLOW UP                                   2 (22.2%)     2 (40%)        1 (25%)    
#>         MISSING                                             4 (44.4%)     1 (20%)        2 (50%)    
#>         SUICIDE                                             2 (22.2%)     1 (20%)        1 (25%)    
#>         UNKNOWN                                             1 (11.1%)     1 (20%)           0       
#> Days from last drug administration                                                                  
#>   n                                                             22           26             19      
#>   <=30                                                      12 (54.5%)   16 (61.5%)     10 (52.6%)  
#>   >30                                                       10 (45.5%)   10 (38.5%)     9 (47.4%)   
#> Primary cause by days from last study drug administration                                           
#>   <=30                                                                                              
#>     n                                                           12           16             10      
#>     ADVERSE EVENT                                            3 (25%)     9 (56.2%)       4 (40%)    
#>     PROGRESSIVE DISEASE                                      3 (25%)      4 (25%)        3 (30%)    
#>     OTHER                                                    6 (50%)     3 (18.8%)       3 (30%)    
#>   >30                                                                                               
#>     n                                                           10           10             9       
#>     ADVERSE EVENT                                            3 (30%)      3 (30%)       3 (33.3%)   
#>     PROGRESSIVE DISEASE                                      4 (40%)      5 (50%)       5 (55.6%)   
#>     OTHER                                                    3 (30%)      2 (20%)       1 (11.1%)