Run the pipeline

Usage

run(object, adam_db, ...)

# S4 method for chevron_tlg
run(object, adam_db, ...)

Arguments

object: (chevron_tlg) input.
adam_db: (dm) object containing the ADaM datasets
...: extra arguments to pass to the check, pre-processing or tlg functions.

Examples

run(aet01_1, syn_test_data())
#>                                                               A: Drug X    B: Placebo    C: Combination
#>                                                                (N=134)       (N=134)        (N=132)    
#> ———————————————————————————————————————————————————————————————————————————————————————————————————————
#> Total number of patients with at least one AE                 122 (91%)    123 (91.8%)    120 (90.9%)  
#> Total number of AEs                                              609           622            703      
#> Total number of deaths                                       22 (16.4%)    26 (19.4%)      19 (14.4%)  
#> Total number of patients withdrawn from study due to an AE    6 (4.5%)      1 (0.7%)        2 (1.5%)   
#> Total number of patients with at least one                                                             
#>   AE with fatal outcome                                      76 (56.7%)    70 (52.2%)      75 (56.8%)  
#>   Serious AE                                                 104 (77.6%)   101 (75.4%)      99 (75%)   
#>   Serious AE leading to withdrawal from treatment              8 (6%)        8 (6%)         7 (5.3%)   
#>   Serious AE leading to dose modification/interruption       36 (26.9%)    31 (23.1%)      26 (19.7%)  
#>   Related Serious AE                                         76 (56.7%)    70 (52.2%)      75 (56.8%)  
#>   AE leading to withdrawal from treatment                    23 (17.2%)    24 (17.9%)      27 (20.5%)  
#>   AE leading to dose modification/interruption               72 (53.7%)    65 (48.5%)      76 (57.6%)  
#>   Related AE                                                 105 (78.4%)   108 (80.6%)    109 (82.6%)  
#>   Related AE leading to withdrawal from treatment             6 (4.5%)      9 (6.7%)       13 (9.8%)   
#>   Related AE leading to dose modification/interruption       31 (23.1%)    31 (23.1%)      32 (24.2%)  
#>   Severe AE (at greatest intensity)                          91 (67.9%)    90 (67.2%)      93 (70.5%)