Diagnostic Plots for MMRM

Usage

g_mmrm_diagnostic(
  object,
  type = c("fit-residual", "q-q-residual"),
  z_threshold = NULL
)

Arguments

object

(tern_mmrm)
model result produced by fit_mmrm().

type

(string)
specifying the type of diagnostic plot to be produced:

• fit-residual: A fitted vs residuals plot, grouped by visits. This allows to see if there is remaining structure in the residuals that might be captured by adding additional covariates to the model.

• q-q-residual: A Q-Q plot for the residuals (i.e. sorted standardized residuals vs. normal quantiles), grouped by visits. Observations with an absolute standardized residual above z_threshold will be labeled.

z_threshold

(numeric)
optional number indicating the normal quantile threshold for the Q-Q plot.

Value

A ggplot2 plot.

Details

Here we use marginal fitted values and residuals. That is, we estimate fitted values, and the difference of those fitted values vs. the observed data are the residuals.

See also

Examples

mmrm_results <- fit_mmrm(
  vars = list(
    response = "FEV1",
    covariates = c("RACE", "SEX"),
    id = "USUBJID",
    arm = "ARMCD",
    visit = "AVISIT"
  ),
  data = mmrm_test_data,
  cor_struct = "unstructured",
  weights_emmeans = "equal"
)
g_mmrm_diagnostic(mmrm_results)

g_mmrm_diagnostic(mmrm_results, type = "q-q-residual")