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[Stable]

Usage

get_datasets(x)

# S3 method for TealDataAbstract
get_datasets(x)

# S3 method for TealDatasetConnector
get_datasets(x)

# S3 method for TealDataset
get_datasets(x)

Arguments

x

(TealData)
object containing datasets.

Value

list or TealDataset objects

Examples


library(magrittr)

# TealData --------
adsl <- cdisc_dataset(
  dataname = "ADSL",
  x = teal.data::example_cdisc_data("ADSL"), ,
  code = "library(teal.data)\nADSL <- teal.data::example_cdisc_data(\"ADSL\")"
)

adae <- cdisc_dataset(
  dataname = "ADAE",
  x = teal.data::example_cdisc_data("ADAE"),
  code = "library(teal.data)\nADAE <- teal.data::example_cdisc_data(\"ADAE\")"
)

rd <- cdisc_data(adsl, adae)
get_datasets(rd)
#> $ADSL
#> A CDISCTealDataset object containing the following data.frame (400 rows and 55 columns):
#>   STUDYID               USUBJID SUBJID SITEID AGE  AGEU SEX
#> 1 AB12345  AB12345-CHN-3-id-128 id-128  CHN-3  32 YEARS   M
#> 2 AB12345 AB12345-CHN-15-id-262 id-262 CHN-15  35 YEARS   M
#> 3 AB12345  AB12345-RUS-3-id-378 id-378  RUS-3  30 YEARS   F
#> 4 AB12345 AB12345-CHN-11-id-220 id-220 CHN-11  26 YEARS   F
#> 5 AB12345  AB12345-CHN-7-id-267 id-267  CHN-7  40 YEARS   M
#> 6 AB12345 AB12345-CHN-15-id-201 id-201 CHN-15  49 YEARS   M
#>                        RACE                 ETHNIC COUNTRY DTHFL         INVID
#> 1                     ASIAN     HISPANIC OR LATINO     CHN     Y  INV ID CHN-3
#> 2 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO     CHN     N INV ID CHN-15
#> 3                     ASIAN NOT HISPANIC OR LATINO     RUS     N  INV ID RUS-3
#> 4                     ASIAN NOT HISPANIC OR LATINO     CHN     N INV ID CHN-11
#> 5                     ASIAN NOT HISPANIC OR LATINO     CHN     N  INV ID CHN-7
#> 6                     ASIAN NOT HISPANIC OR LATINO     CHN     Y INV ID CHN-15
#>           INVNAM            ARM ARMCD         ACTARM ACTARMCD         TRT01P
#> 1  Dr. CHN-3 Doe      A: Drug X ARM A      A: Drug X    ARM A      A: Drug X
#> 2 Dr. CHN-15 Doe C: Combination ARM C C: Combination    ARM C C: Combination
#> 3  Dr. RUS-3 Doe C: Combination ARM C C: Combination    ARM C C: Combination
#> 4 Dr. CHN-11 Doe     B: Placebo ARM B     B: Placebo    ARM B     B: Placebo
#> 5  Dr. CHN-7 Doe     B: Placebo ARM B     B: Placebo    ARM B     B: Placebo
#> 6 Dr. CHN-15 Doe C: Combination ARM C C: Combination    ARM C C: Combination
#>           TRT01A         TRT02P         TRT02A REGION1 STRATA1 STRATA2
#> 1      A: Drug X     B: Placebo      A: Drug X    Asia       C      S2
#> 2 C: Combination     B: Placebo C: Combination    Asia       C      S1
#> 3 C: Combination      A: Drug X     B: Placebo Eurasia       A      S1
#> 4     B: Placebo     B: Placebo     B: Placebo    Asia       B      S2
#> 5     B: Placebo C: Combination      A: Drug X    Asia       C      S1
#> 6 C: Combination     B: Placebo C: Combination    Asia       C      S2
#>      BMRKR1 BMRKR2 ITTFL SAFFL BMEASIFL BEP01FL AEWITHFL     RANDDT
#> 1 14.424934 MEDIUM     Y     Y        Y       Y        N 2019-02-22
#> 2  4.055463    LOW     Y     Y        N       N        Y 2019-02-26
#> 3  2.803240   HIGH     Y     Y        Y       N        N 2019-02-24
#> 4 10.262734 MEDIUM     Y     Y        Y       Y        N 2019-02-27
#> 5  6.206763    LOW     Y     Y        N       N        N 2019-03-01
#> 6  6.906799 MEDIUM     Y     Y        Y       N        N 2019-03-05
#>               TRTSDTM             TRTEDTM           TRT01SDTM
#> 1 2019-02-24 11:09:25 2022-02-12 04:28:08 2019-02-24 11:09:25
#> 2 2019-02-26 09:05:10 2022-02-26 03:05:10 2019-02-26 09:05:10
#> 3 2019-02-28 03:19:22 2022-02-27 21:19:22 2019-02-28 03:19:22
#> 4 2019-03-01 13:33:19 2022-03-01 07:33:19 2019-03-01 13:33:19
#> 5 2019-03-02 00:09:33 2022-03-01 18:09:33 2019-03-02 00:09:33
#> 6 2019-03-05 15:24:07 2022-02-19 04:06:48 2019-03-05 15:24:07
#>             TRT01EDTM           TRT02SDTM           TRT02EDTM
#> 1 2021-02-11 22:28:08 2021-02-11 22:28:08 2022-02-12 04:28:08
#> 2 2021-02-25 21:05:10 2021-02-25 21:05:10 2022-02-26 03:05:10
#> 3 2021-02-27 15:19:22 2021-02-27 15:19:22 2022-02-27 21:19:22
#> 4 2021-03-01 01:33:19 2021-03-01 01:33:19 2022-03-01 07:33:19
#> 5 2021-03-01 12:09:33 2021-03-01 12:09:33 2022-03-01 18:09:33
#> 6 2021-02-18 22:06:48 2021-02-18 22:06:48 2022-02-19 04:06:48
#>              AP01SDTM            AP01EDTM            AP02SDTM
#> 1 2019-02-24 11:09:25 2021-02-11 22:28:08 2021-02-11 22:28:08
#> 2 2019-02-26 09:05:10 2021-02-25 21:05:10 2021-02-25 21:05:10
#> 3 2019-02-28 03:19:22 2021-02-27 15:19:22 2021-02-27 15:19:22
#> 4 2019-03-01 13:33:19 2021-03-01 01:33:19 2021-03-01 01:33:19
#> 5 2019-03-02 00:09:33 2021-03-01 12:09:33 2021-03-01 12:09:33
#> 6 2019-03-05 15:24:07 2021-02-18 22:06:48 2021-02-18 22:06:48
#>              AP02EDTM       EOSSTT       EOTSTT      EOSDT EOSDY DCSREAS
#> 1 2022-02-12 04:28:08 DISCONTINUED DISCONTINUED 2022-02-12  1084   DEATH
#> 2 2022-02-26 03:05:10    COMPLETED    COMPLETED 2022-02-26  1096    <NA>
#> 3 2022-02-27 21:19:22    COMPLETED    COMPLETED 2022-02-27  1096    <NA>
#> 4 2022-03-01 07:33:19    COMPLETED    COMPLETED 2022-03-01  1096    <NA>
#> 5 2022-03-01 18:09:33    COMPLETED    COMPLETED 2022-03-01  1096    <NA>
#> 6 2022-02-19 04:06:48 DISCONTINUED DISCONTINUED 2022-02-19  1082   DEATH
#>        DTHDT       DTHCAUS        DTHCAT LDDTHELD LDDTHGR1   LSTALVDT DTHADY
#> 1 2022-03-06 ADVERSE EVENT ADVERSE EVENT       22     <=30 2022-03-06   1105
#> 2       <NA>          <NA>          <NA>       NA     <NA> 2022-03-17     NA
#> 3       <NA>          <NA>          <NA>       NA     <NA> 2022-03-11     NA
#> 4       <NA>          <NA>          <NA>       NA     <NA> 2022-03-26     NA
#> 5       <NA>          <NA>          <NA>       NA     <NA> 2022-03-15     NA
#> 6 2022-02-22 ADVERSE EVENT ADVERSE EVENT        3     <=30 2022-02-22   1084
#>   ADTHAUT
#> 1     Yes
#> 2    <NA>
#> 3    <NA>
#> 4    <NA>
#> 5    <NA>
#> 6     Yes
#> ...
#> 
#> $ADAE
#> A CDISCTealDataset object containing the following data.frame (1934 rows and 92 columns):
#>   STUDYID              USUBJID SUBJID SITEID AGE  AGEU SEX  RACE
#> 1 AB12345 AB12345-BRA-1-id-134 id-134  BRA-1  47 YEARS   M WHITE
#> 2 AB12345 AB12345-BRA-1-id-134 id-134  BRA-1  47 YEARS   M WHITE
#> 3 AB12345 AB12345-BRA-1-id-134 id-134  BRA-1  47 YEARS   M WHITE
#> 4 AB12345 AB12345-BRA-1-id-134 id-134  BRA-1  47 YEARS   M WHITE
#> 5 AB12345 AB12345-BRA-1-id-141 id-141  BRA-1  35 YEARS   F WHITE
#> 6 AB12345 AB12345-BRA-1-id-141 id-141  BRA-1  35 YEARS   F WHITE
#>                   ETHNIC COUNTRY DTHFL        INVID        INVNAM
#> 1 NOT HISPANIC OR LATINO     BRA     Y INV ID BRA-1 Dr. BRA-1 Doe
#> 2 NOT HISPANIC OR LATINO     BRA     Y INV ID BRA-1 Dr. BRA-1 Doe
#> 3 NOT HISPANIC OR LATINO     BRA     Y INV ID BRA-1 Dr. BRA-1 Doe
#> 4 NOT HISPANIC OR LATINO     BRA     Y INV ID BRA-1 Dr. BRA-1 Doe
#> 5 NOT HISPANIC OR LATINO     BRA     N INV ID BRA-1 Dr. BRA-1 Doe
#> 6 NOT HISPANIC OR LATINO     BRA     N INV ID BRA-1 Dr. BRA-1 Doe
#>              ARM ARMCD         ACTARM ACTARMCD         TRT01P         TRT01A
#> 1      A: Drug X ARM A      A: Drug X    ARM A      A: Drug X      A: Drug X
#> 2      A: Drug X ARM A      A: Drug X    ARM A      A: Drug X      A: Drug X
#> 3      A: Drug X ARM A      A: Drug X    ARM A      A: Drug X      A: Drug X
#> 4      A: Drug X ARM A      A: Drug X    ARM A      A: Drug X      A: Drug X
#> 5 C: Combination ARM C C: Combination    ARM C C: Combination C: Combination
#> 6 C: Combination ARM C C: Combination    ARM C C: Combination C: Combination
#>           TRT02P         TRT02A       REGION1 STRATA1 STRATA2   BMRKR1 BMRKR2
#> 1     B: Placebo      A: Drug X South America       B      S2 6.462991    LOW
#> 2     B: Placebo      A: Drug X South America       B      S2 6.462991    LOW
#> 3     B: Placebo      A: Drug X South America       B      S2 6.462991    LOW
#> 4     B: Placebo      A: Drug X South America       B      S2 6.462991    LOW
#> 5 C: Combination C: Combination South America       B      S1 7.516076   HIGH
#> 6 C: Combination C: Combination South America       B      S1 7.516076   HIGH
#>   ITTFL SAFFL BMEASIFL BEP01FL AEWITHFL     RANDDT             TRTSDTM
#> 1     Y     Y        Y       N        N 2020-11-03 2020-11-04 04:08:58
#> 2     Y     Y        Y       N        N 2020-11-03 2020-11-04 04:08:58
#> 3     Y     Y        Y       N        N 2020-11-03 2020-11-04 04:08:58
#> 4     Y     Y        Y       N        N 2020-11-03 2020-11-04 04:08:58
#> 5     Y     Y        Y       Y        N 2020-07-22 2020-07-25 14:26:21
#> 6     Y     Y        Y       Y        N 2020-07-22 2020-07-25 14:26:21
#>               TRTEDTM           TRT01SDTM           TRT01EDTM
#> 1 2022-02-20 03:33:55 2020-11-04 04:08:58 2021-02-19 21:33:55
#> 2 2022-02-20 03:33:55 2020-11-04 04:08:58 2021-02-19 21:33:55
#> 3 2022-02-20 03:33:55 2020-11-04 04:08:58 2021-02-19 21:33:55
#> 4 2022-02-20 03:33:55 2020-11-04 04:08:58 2021-02-19 21:33:55
#> 5 2023-07-26 08:26:21 2020-07-25 14:26:21 2022-07-26 02:26:21
#> 6 2023-07-26 08:26:21 2020-07-25 14:26:21 2022-07-26 02:26:21
#>             TRT02SDTM           TRT02EDTM            AP01SDTM
#> 1 2021-02-19 21:33:55 2022-02-20 03:33:55 2020-11-04 04:08:58
#> 2 2021-02-19 21:33:55 2022-02-20 03:33:55 2020-11-04 04:08:58
#> 3 2021-02-19 21:33:55 2022-02-20 03:33:55 2020-11-04 04:08:58
#> 4 2021-02-19 21:33:55 2022-02-20 03:33:55 2020-11-04 04:08:58
#> 5 2022-07-26 02:26:21 2023-07-26 08:26:21 2020-07-25 14:26:21
#> 6 2022-07-26 02:26:21 2023-07-26 08:26:21 2020-07-25 14:26:21
#>              AP01EDTM            AP02SDTM            AP02EDTM       EOSSTT
#> 1 2021-02-19 21:33:55 2021-02-19 21:33:55 2022-02-20 03:33:55 DISCONTINUED
#> 2 2021-02-19 21:33:55 2021-02-19 21:33:55 2022-02-20 03:33:55 DISCONTINUED
#> 3 2021-02-19 21:33:55 2021-02-19 21:33:55 2022-02-20 03:33:55 DISCONTINUED
#> 4 2021-02-19 21:33:55 2021-02-19 21:33:55 2022-02-20 03:33:55 DISCONTINUED
#> 5 2022-07-26 02:26:21 2022-07-26 02:26:21 2023-07-26 08:26:21    COMPLETED
#> 6 2022-07-26 02:26:21 2022-07-26 02:26:21 2023-07-26 08:26:21    COMPLETED
#>         EOTSTT      EOSDT EOSDY DCSREAS      DTHDT       DTHCAUS        DTHCAT
#> 1 DISCONTINUED 2022-02-20   473   DEATH 2022-03-16 ADVERSE EVENT ADVERSE EVENT
#> 2 DISCONTINUED 2022-02-20   473   DEATH 2022-03-16 ADVERSE EVENT ADVERSE EVENT
#> 3 DISCONTINUED 2022-02-20   473   DEATH 2022-03-16 ADVERSE EVENT ADVERSE EVENT
#> 4 DISCONTINUED 2022-02-20   473   DEATH 2022-03-16 ADVERSE EVENT ADVERSE EVENT
#> 5    COMPLETED 2023-07-26  1096    <NA>       <NA>          <NA>          <NA>
#> 6    COMPLETED 2023-07-26  1096    <NA>       <NA>          <NA>          <NA>
#>   LDDTHELD LDDTHGR1   LSTALVDT DTHADY ADTHAUT ASEQ AESEQ        AETERM
#> 1       24     <=30 2022-03-16    496     Yes    1     1 trm B.2.1.2.1
#> 2       24     <=30 2022-03-16    496     Yes    2     2 trm D.1.1.4.2
#> 3       24     <=30 2022-03-16    496     Yes    3     3 trm A.1.1.1.2
#> 4       24     <=30 2022-03-16    496     Yes    4     4 trm A.1.1.1.2
#> 5       NA     <NA> 2023-08-08     NA    <NA>    1     1 trm B.2.1.2.1
#> 6       NA     <NA> 2023-08-08     NA    <NA>    2     2 trm D.2.1.5.3
#>           AELLT       AEDECOD       AEHLT     AEHLGT AEBODSYS AESOC    AESEV
#> 1 llt B.2.1.2.1 dcd B.2.1.2.1 hlt B.2.1.2 hlgt B.2.1   cl B.2  cl B MODERATE
#> 2 llt D.1.1.4.2 dcd D.1.1.4.2 hlt D.1.1.4 hlgt D.1.1   cl D.1  cl D MODERATE
#> 3 llt A.1.1.1.2 dcd A.1.1.1.2 hlt A.1.1.1 hlgt A.1.1   cl A.1  cl A MODERATE
#> 4 llt A.1.1.1.2 dcd A.1.1.1.2 hlt A.1.1.1 hlgt A.1.1   cl A.1  cl A MODERATE
#> 5 llt B.2.1.2.1 dcd B.2.1.2.1 hlt B.2.1.2 hlgt B.2.1   cl B.2  cl B MODERATE
#> 6 llt D.2.1.5.3 dcd D.2.1.5.3 hlt D.2.1.5 hlgt D.2.1   cl D.2  cl D     MILD
#>   AESER            AEACN AEREL                AEOUT AESDTH AESCONG AESDISAB
#> 1     N DOSE NOT CHANGED     N RECOVERING/RESOLVING      N       N        Y
#> 2     N DOSE NOT CHANGED     N RECOVERING/RESOLVING      N       N        Y
#> 3     Y DOSE NOT CHANGED     N RECOVERING/RESOLVING      N       N        Y
#> 4     Y   DRUG WITHDRAWN     N RECOVERING/RESOLVING      N       Y        N
#> 5     N   DOSE INCREASED     N   RECOVERED/RESOLVED      N       N        N
#> 6     N   DOSE INCREASED     Y   RECOVERED/RESOLVED      N       N        Y
#>   AESHOSP AESLIFE AESMIE TRTEMFL AECONTRT              ASTDTM
#> 1       N       N      N       Y        Y 2021-04-15 04:08:58
#> 2       N       N      N       Y        N 2021-05-19 04:08:58
#> 3       N       N      N       Y        Y 2021-09-21 04:08:58
#> 4       N       N      N       Y        N 2021-12-02 04:08:58
#> 5       Y       N      N       Y        Y 2021-08-16 14:26:21
#> 6       N       N      N       Y        N 2021-10-23 14:26:21
#>                AENDTM ASTDY AENDY            LDOSEDTM    LDRELTM AETOXGR
#> 1 2021-10-04 04:08:58   162   334 2020-11-07 09:05:04 228663.896       3
#> 2 2021-10-31 04:08:58   196   361 2021-05-17 07:21:09   2687.814       3
#> 3 2022-02-16 04:08:58   321   469 2021-05-23 15:14:37 173574.345       2
#> 4 2022-01-13 04:08:58   393   435 2021-03-19 08:52:05 371236.878       2
#> 5 2021-08-26 14:26:21   387   397 2021-07-22 06:04:04  36502.291       3
#> 6 2023-07-12 14:26:21   455  1082 2021-07-16 21:30:39 142135.710       1
#>   SMQ01NAM SMQ02NAM SMQ01SC SMQ02SC                  CQ01NAM ANL01FL
#> 1     <NA>     <NA>    <NA>    <NA>                     <NA>       Y
#> 2     <NA>     <NA>    <NA>    <NA>                     <NA>       Y
#> 3     <NA>     <NA>    <NA>    <NA>                     <NA>       Y
#> 4     <NA>     <NA>    <NA>    <NA>                     <NA>       Y
#> 5     <NA>     <NA>    <NA>    <NA>                     <NA>       Y
#> 6     <NA>     <NA>    <NA>    <NA> D.2.1.5.3/A.1.1.1.1 AESI       Y
#>             AERELNST                        AEACNOTH
#> 1               NONE               PROCEDURE/SURGERY
#> 2 CONCURRENT ILLNESS                      MEDICATION
#> 3 CONCURRENT ILLNESS SUBJECT DISCONTINUED FROM STUDY
#> 4 CONCURRENT ILLNESS SUBJECT DISCONTINUED FROM STUDY
#> 5 CONCURRENT ILLNESS               PROCEDURE/SURGERY
#> 6 CONCURRENT ILLNESS                      MEDICATION
#> ...
#> 

# TealDataConnector --------
random_data_connector <- function(dataname) {
  fun_dataset_connector(
    dataname = dataname,
    fun = teal.data::example_cdisc_data,
    fun_args = list(dataname = dataname),
  )
}

adsl_cf <- callable_function(teal.data::example_cdisc_data) %>%
  set_args(list(dataname = "ADSL"))
adsl <- cdisc_dataset_connector(
  dataname = "ADSL",
  pull_callable = adsl_cf,
  keys = get_cdisc_keys("ADSL")
)
adlb_cf <- callable_function(teal.data::example_cdisc_data) %>%
  set_args(list(dataname = "ADLB"))
adlb <- cdisc_dataset_connector(
  dataname = "ADLB",
  pull_callable = adlb_cf,
  keys = get_cdisc_keys("ADLB")
)

rdc <- relational_data_connector(
  connection = data_connection(),
  connectors = list(adsl, adlb)
)

rdc$set_ui(function(id, connection, connectors) p("Example UI"))
rdc$set_server(
  function(id, connection, connectors) {
    moduleServer(
      id = id,
      module = function(input, output, session) {
        # Note this is simplified as we are not opening a real connection here
        for (connector in connectors) {
          set_args(connector, args = list(name = input$name))
          # pull each dataset
          connector$get_server()(id = connector$get_dataname())
          if (connector$is_failed()) {
            break
          }
        }
      }
    )
  }
)
if (FALSE) {
load_datasets(rdc)
get_datasets(rdc)
}

# TealData --------
if (FALSE) {
drc <- cdisc_data(rdc, adae)
get_datasets(drc)
}

# TealDatasetConnector --------
adsl_cf <- callable_function(teal.data::example_cdisc_data) %>%
  set_args(list(dataname = "ADSL"))
rdc <- cdisc_dataset_connector("ADSL", adsl_cf, keys = get_cdisc_keys("ADSL"))
if (FALSE) {
load_datasets(rdc)
get_datasets(rdc)
}

# TealDataset --------
adsl <- cdisc_dataset(
  dataname = "ADSL",
  x = teal.data::example_cdisc_data("ADSL"),
  code = "library(teal.data)\nADSL <- example_cdisc_data(\"ADSL\")"
)

get_datasets(adsl)
#> A CDISCTealDataset object containing the following data.frame (400 rows and 55 columns):
#>   STUDYID               USUBJID SUBJID SITEID AGE  AGEU SEX
#> 1 AB12345  AB12345-CHN-3-id-128 id-128  CHN-3  32 YEARS   M
#> 2 AB12345 AB12345-CHN-15-id-262 id-262 CHN-15  35 YEARS   M
#> 3 AB12345  AB12345-RUS-3-id-378 id-378  RUS-3  30 YEARS   F
#> 4 AB12345 AB12345-CHN-11-id-220 id-220 CHN-11  26 YEARS   F
#> 5 AB12345  AB12345-CHN-7-id-267 id-267  CHN-7  40 YEARS   M
#> 6 AB12345 AB12345-CHN-15-id-201 id-201 CHN-15  49 YEARS   M
#>                        RACE                 ETHNIC COUNTRY DTHFL         INVID
#> 1                     ASIAN     HISPANIC OR LATINO     CHN     Y  INV ID CHN-3
#> 2 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO     CHN     N INV ID CHN-15
#> 3                     ASIAN NOT HISPANIC OR LATINO     RUS     N  INV ID RUS-3
#> 4                     ASIAN NOT HISPANIC OR LATINO     CHN     N INV ID CHN-11
#> 5                     ASIAN NOT HISPANIC OR LATINO     CHN     N  INV ID CHN-7
#> 6                     ASIAN NOT HISPANIC OR LATINO     CHN     Y INV ID CHN-15
#>           INVNAM            ARM ARMCD         ACTARM ACTARMCD         TRT01P
#> 1  Dr. CHN-3 Doe      A: Drug X ARM A      A: Drug X    ARM A      A: Drug X
#> 2 Dr. CHN-15 Doe C: Combination ARM C C: Combination    ARM C C: Combination
#> 3  Dr. RUS-3 Doe C: Combination ARM C C: Combination    ARM C C: Combination
#> 4 Dr. CHN-11 Doe     B: Placebo ARM B     B: Placebo    ARM B     B: Placebo
#> 5  Dr. CHN-7 Doe     B: Placebo ARM B     B: Placebo    ARM B     B: Placebo
#> 6 Dr. CHN-15 Doe C: Combination ARM C C: Combination    ARM C C: Combination
#>           TRT01A         TRT02P         TRT02A REGION1 STRATA1 STRATA2
#> 1      A: Drug X     B: Placebo      A: Drug X    Asia       C      S2
#> 2 C: Combination     B: Placebo C: Combination    Asia       C      S1
#> 3 C: Combination      A: Drug X     B: Placebo Eurasia       A      S1
#> 4     B: Placebo     B: Placebo     B: Placebo    Asia       B      S2
#> 5     B: Placebo C: Combination      A: Drug X    Asia       C      S1
#> 6 C: Combination     B: Placebo C: Combination    Asia       C      S2
#>      BMRKR1 BMRKR2 ITTFL SAFFL BMEASIFL BEP01FL AEWITHFL     RANDDT
#> 1 14.424934 MEDIUM     Y     Y        Y       Y        N 2019-02-22
#> 2  4.055463    LOW     Y     Y        N       N        Y 2019-02-26
#> 3  2.803240   HIGH     Y     Y        Y       N        N 2019-02-24
#> 4 10.262734 MEDIUM     Y     Y        Y       Y        N 2019-02-27
#> 5  6.206763    LOW     Y     Y        N       N        N 2019-03-01
#> 6  6.906799 MEDIUM     Y     Y        Y       N        N 2019-03-05
#>               TRTSDTM             TRTEDTM           TRT01SDTM
#> 1 2019-02-24 11:09:25 2022-02-12 04:28:08 2019-02-24 11:09:25
#> 2 2019-02-26 09:05:10 2022-02-26 03:05:10 2019-02-26 09:05:10
#> 3 2019-02-28 03:19:22 2022-02-27 21:19:22 2019-02-28 03:19:22
#> 4 2019-03-01 13:33:19 2022-03-01 07:33:19 2019-03-01 13:33:19
#> 5 2019-03-02 00:09:33 2022-03-01 18:09:33 2019-03-02 00:09:33
#> 6 2019-03-05 15:24:07 2022-02-19 04:06:48 2019-03-05 15:24:07
#>             TRT01EDTM           TRT02SDTM           TRT02EDTM
#> 1 2021-02-11 22:28:08 2021-02-11 22:28:08 2022-02-12 04:28:08
#> 2 2021-02-25 21:05:10 2021-02-25 21:05:10 2022-02-26 03:05:10
#> 3 2021-02-27 15:19:22 2021-02-27 15:19:22 2022-02-27 21:19:22
#> 4 2021-03-01 01:33:19 2021-03-01 01:33:19 2022-03-01 07:33:19
#> 5 2021-03-01 12:09:33 2021-03-01 12:09:33 2022-03-01 18:09:33
#> 6 2021-02-18 22:06:48 2021-02-18 22:06:48 2022-02-19 04:06:48
#>              AP01SDTM            AP01EDTM            AP02SDTM
#> 1 2019-02-24 11:09:25 2021-02-11 22:28:08 2021-02-11 22:28:08
#> 2 2019-02-26 09:05:10 2021-02-25 21:05:10 2021-02-25 21:05:10
#> 3 2019-02-28 03:19:22 2021-02-27 15:19:22 2021-02-27 15:19:22
#> 4 2019-03-01 13:33:19 2021-03-01 01:33:19 2021-03-01 01:33:19
#> 5 2019-03-02 00:09:33 2021-03-01 12:09:33 2021-03-01 12:09:33
#> 6 2019-03-05 15:24:07 2021-02-18 22:06:48 2021-02-18 22:06:48
#>              AP02EDTM       EOSSTT       EOTSTT      EOSDT EOSDY DCSREAS
#> 1 2022-02-12 04:28:08 DISCONTINUED DISCONTINUED 2022-02-12  1084   DEATH
#> 2 2022-02-26 03:05:10    COMPLETED    COMPLETED 2022-02-26  1096    <NA>
#> 3 2022-02-27 21:19:22    COMPLETED    COMPLETED 2022-02-27  1096    <NA>
#> 4 2022-03-01 07:33:19    COMPLETED    COMPLETED 2022-03-01  1096    <NA>
#> 5 2022-03-01 18:09:33    COMPLETED    COMPLETED 2022-03-01  1096    <NA>
#> 6 2022-02-19 04:06:48 DISCONTINUED DISCONTINUED 2022-02-19  1082   DEATH
#>        DTHDT       DTHCAUS        DTHCAT LDDTHELD LDDTHGR1   LSTALVDT DTHADY
#> 1 2022-03-06 ADVERSE EVENT ADVERSE EVENT       22     <=30 2022-03-06   1105
#> 2       <NA>          <NA>          <NA>       NA     <NA> 2022-03-17     NA
#> 3       <NA>          <NA>          <NA>       NA     <NA> 2022-03-11     NA
#> 4       <NA>          <NA>          <NA>       NA     <NA> 2022-03-26     NA
#> 5       <NA>          <NA>          <NA>       NA     <NA> 2022-03-15     NA
#> 6 2022-02-22 ADVERSE EVENT ADVERSE EVENT        3     <=30 2022-02-22   1084
#>   ADTHAUT
#> 1     Yes
#> 2    <NA>
#> 3    <NA>
#> 4    <NA>
#> 5    <NA>
#> 6     Yes
#> ...