Tumor Response Analysis Dataset (ADTR)
radtr.Rd![[Stable]](figures/lifecycle-stable.svg)
Function for generating a random Tumor Response Analysis Dataset for a given Subject-Level Analysis Dataset.
Arguments
- adsl
(
data.frame)
Subject-Level Analysis Dataset (ADSL).- param
(
character vector)
Parameter values.- paramcd
(
character vector)
Parameter code values.- seed
(
numeric)
Seed to use for reproducible random number generation.- cached
boolean whether the cached ADTR data
cadtrshould be returned or new data should be generated. If set toTRUEthen the other arguments toradtrwill be ignored.- ...
Additional arguments to be passed to
radrs.
Details
One record per subject per parameter per analysis visit per analysis date.
Keys: STUDYID, USUBJID, PARAMCD, BASETYPE, AVISITN, DTYPE
Examples
library(random.cdisc.data)
adsl <- radsl(N = 10, seed = 1, study_duration = 2)
adtr <- radtr(adsl, seed = 2)
adtr
#> STUDYID USUBJID SUBJID SITEID AGE AGEU SEX
#> 1 AB12345 AB12345-BRA-1-id-9 id-9 BRA-1 35 YEARS F
#> 2 AB12345 AB12345-BRA-1-id-9 id-9 BRA-1 35 YEARS F
#> 3 AB12345 AB12345-BRA-1-id-9 id-9 BRA-1 35 YEARS F
#> 4 AB12345 AB12345-BRA-1-id-9 id-9 BRA-1 35 YEARS F
#> 5 AB12345 AB12345-BRA-1-id-9 id-9 BRA-1 35 YEARS F
#> 6 AB12345 AB12345-BRA-1-id-9 id-9 BRA-1 35 YEARS F
#> 7 AB12345 AB12345-BRA-1-id-9 id-9 BRA-1 35 YEARS F
#> 8 AB12345 AB12345-BRA-9-id-8 id-8 BRA-9 31 YEARS F
#> 9 AB12345 AB12345-BRA-9-id-8 id-8 BRA-9 31 YEARS F
#> 10 AB12345 AB12345-BRA-9-id-8 id-8 BRA-9 31 YEARS F
#> 11 AB12345 AB12345-BRA-9-id-8 id-8 BRA-9 31 YEARS F
#> 12 AB12345 AB12345-BRA-9-id-8 id-8 BRA-9 31 YEARS F
#> 13 AB12345 AB12345-BRA-9-id-8 id-8 BRA-9 31 YEARS F
#> 14 AB12345 AB12345-BRA-9-id-8 id-8 BRA-9 31 YEARS F
#> 15 AB12345 AB12345-CHN-11-id-1 id-1 CHN-11 35 YEARS F
#> 16 AB12345 AB12345-CHN-11-id-1 id-1 CHN-11 35 YEARS F
#> 17 AB12345 AB12345-CHN-11-id-1 id-1 CHN-11 35 YEARS F
#> 18 AB12345 AB12345-CHN-11-id-1 id-1 CHN-11 35 YEARS F
#> 19 AB12345 AB12345-CHN-11-id-1 id-1 CHN-11 35 YEARS F
#> 20 AB12345 AB12345-CHN-11-id-1 id-1 CHN-11 35 YEARS F
#> 21 AB12345 AB12345-CHN-11-id-1 id-1 CHN-11 35 YEARS F
#> 22 AB12345 AB12345-CHN-11-id-2 id-2 CHN-11 35 YEARS M
#> 23 AB12345 AB12345-CHN-11-id-2 id-2 CHN-11 35 YEARS M
#> 24 AB12345 AB12345-CHN-11-id-2 id-2 CHN-11 35 YEARS M
#> 25 AB12345 AB12345-CHN-11-id-2 id-2 CHN-11 35 YEARS M
#> 26 AB12345 AB12345-CHN-11-id-2 id-2 CHN-11 35 YEARS M
#> 27 AB12345 AB12345-CHN-11-id-2 id-2 CHN-11 35 YEARS M
#> 28 AB12345 AB12345-CHN-11-id-2 id-2 CHN-11 35 YEARS M
#> 29 AB12345 AB12345-CHN-3-id-10 id-10 CHN-3 35 YEARS M
#> 30 AB12345 AB12345-CHN-3-id-10 id-10 CHN-3 35 YEARS M
#> 31 AB12345 AB12345-CHN-3-id-10 id-10 CHN-3 35 YEARS M
#> 32 AB12345 AB12345-CHN-3-id-10 id-10 CHN-3 35 YEARS M
#> 33 AB12345 AB12345-CHN-3-id-10 id-10 CHN-3 35 YEARS M
#> 34 AB12345 AB12345-CHN-3-id-10 id-10 CHN-3 35 YEARS M
#> 35 AB12345 AB12345-CHN-3-id-10 id-10 CHN-3 35 YEARS M
#> 36 AB12345 AB12345-CHN-3-id-5 id-5 CHN-3 36 YEARS F
#> 37 AB12345 AB12345-CHN-3-id-5 id-5 CHN-3 36 YEARS F
#> 38 AB12345 AB12345-CHN-3-id-5 id-5 CHN-3 36 YEARS F
#> 39 AB12345 AB12345-CHN-3-id-5 id-5 CHN-3 36 YEARS F
#> 40 AB12345 AB12345-CHN-3-id-5 id-5 CHN-3 36 YEARS F
#> 41 AB12345 AB12345-CHN-3-id-5 id-5 CHN-3 36 YEARS F
#> 42 AB12345 AB12345-CHN-3-id-5 id-5 CHN-3 36 YEARS F
#> 43 AB12345 AB12345-JPN-4-id-7 id-7 JPN-4 30 YEARS F
#> 44 AB12345 AB12345-JPN-4-id-7 id-7 JPN-4 30 YEARS F
#> 45 AB12345 AB12345-JPN-4-id-7 id-7 JPN-4 30 YEARS F
#> 46 AB12345 AB12345-JPN-4-id-7 id-7 JPN-4 30 YEARS F
#> 47 AB12345 AB12345-JPN-4-id-7 id-7 JPN-4 30 YEARS F
#> 48 AB12345 AB12345-JPN-4-id-7 id-7 JPN-4 30 YEARS F
#> 49 AB12345 AB12345-JPN-4-id-7 id-7 JPN-4 30 YEARS F
#> 50 AB12345 AB12345-RUS-1-id-4 id-4 RUS-1 36 YEARS M
#> 51 AB12345 AB12345-RUS-1-id-4 id-4 RUS-1 36 YEARS M
#> 52 AB12345 AB12345-RUS-1-id-4 id-4 RUS-1 36 YEARS M
#> 53 AB12345 AB12345-RUS-1-id-4 id-4 RUS-1 36 YEARS M
#> 54 AB12345 AB12345-RUS-1-id-4 id-4 RUS-1 36 YEARS M
#> 55 AB12345 AB12345-RUS-1-id-4 id-4 RUS-1 36 YEARS M
#> 56 AB12345 AB12345-RUS-1-id-4 id-4 RUS-1 36 YEARS M
#> 57 AB12345 AB12345-RUS-1-id-6 id-6 RUS-1 36 YEARS F
#> 58 AB12345 AB12345-RUS-1-id-6 id-6 RUS-1 36 YEARS F
#> 59 AB12345 AB12345-RUS-1-id-6 id-6 RUS-1 36 YEARS F
#> 60 AB12345 AB12345-RUS-1-id-6 id-6 RUS-1 36 YEARS F
#> 61 AB12345 AB12345-RUS-1-id-6 id-6 RUS-1 36 YEARS F
#> 62 AB12345 AB12345-RUS-1-id-6 id-6 RUS-1 36 YEARS F
#> 63 AB12345 AB12345-RUS-1-id-6 id-6 RUS-1 36 YEARS F
#> 64 AB12345 AB12345-USA-13-id-3 id-3 USA-13 35 YEARS F
#> 65 AB12345 AB12345-USA-13-id-3 id-3 USA-13 35 YEARS F
#> 66 AB12345 AB12345-USA-13-id-3 id-3 USA-13 35 YEARS F
#> 67 AB12345 AB12345-USA-13-id-3 id-3 USA-13 35 YEARS F
#> 68 AB12345 AB12345-USA-13-id-3 id-3 USA-13 35 YEARS F
#> 69 AB12345 AB12345-USA-13-id-3 id-3 USA-13 35 YEARS F
#> 70 AB12345 AB12345-USA-13-id-3 id-3 USA-13 35 YEARS F
#> RACE ETHNIC COUNTRY DTHFL
#> 1 BLACK OR AFRICAN AMERICAN UNKNOWN BRA N
#> 2 BLACK OR AFRICAN AMERICAN UNKNOWN BRA N
#> 3 BLACK OR AFRICAN AMERICAN UNKNOWN BRA N
#> 4 BLACK OR AFRICAN AMERICAN UNKNOWN BRA N
#> 5 BLACK OR AFRICAN AMERICAN UNKNOWN BRA N
#> 6 BLACK OR AFRICAN AMERICAN UNKNOWN BRA N
#> 7 BLACK OR AFRICAN AMERICAN UNKNOWN BRA N
#> 8 ASIAN NOT HISPANIC OR LATINO BRA Y
#> 9 ASIAN NOT HISPANIC OR LATINO BRA Y
#> 10 ASIAN NOT HISPANIC OR LATINO BRA Y
#> 11 ASIAN NOT HISPANIC OR LATINO BRA Y
#> 12 ASIAN NOT HISPANIC OR LATINO BRA Y
#> 13 ASIAN NOT HISPANIC OR LATINO BRA Y
#> 14 ASIAN NOT HISPANIC OR LATINO BRA Y
#> 15 WHITE NOT HISPANIC OR LATINO CHN Y
#> 16 WHITE NOT HISPANIC OR LATINO CHN Y
#> 17 WHITE NOT HISPANIC OR LATINO CHN Y
#> 18 WHITE NOT HISPANIC OR LATINO CHN Y
#> 19 WHITE NOT HISPANIC OR LATINO CHN Y
#> 20 WHITE NOT HISPANIC OR LATINO CHN Y
#> 21 WHITE NOT HISPANIC OR LATINO CHN Y
#> 22 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO CHN N
#> 23 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO CHN N
#> 24 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO CHN N
#> 25 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO CHN N
#> 26 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO CHN N
#> 27 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO CHN N
#> 28 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO CHN N
#> 29 ASIAN NOT HISPANIC OR LATINO CHN N
#> 30 ASIAN NOT HISPANIC OR LATINO CHN N
#> 31 ASIAN NOT HISPANIC OR LATINO CHN N
#> 32 ASIAN NOT HISPANIC OR LATINO CHN N
#> 33 ASIAN NOT HISPANIC OR LATINO CHN N
#> 34 ASIAN NOT HISPANIC OR LATINO CHN N
#> 35 ASIAN NOT HISPANIC OR LATINO CHN N
#> 36 ASIAN NOT HISPANIC OR LATINO CHN N
#> 37 ASIAN NOT HISPANIC OR LATINO CHN N
#> 38 ASIAN NOT HISPANIC OR LATINO CHN N
#> 39 ASIAN NOT HISPANIC OR LATINO CHN N
#> 40 ASIAN NOT HISPANIC OR LATINO CHN N
#> 41 ASIAN NOT HISPANIC OR LATINO CHN N
#> 42 ASIAN NOT HISPANIC OR LATINO CHN N
#> 43 ASIAN NOT HISPANIC OR LATINO JPN N
#> 44 ASIAN NOT HISPANIC OR LATINO JPN N
#> 45 ASIAN NOT HISPANIC OR LATINO JPN N
#> 46 ASIAN NOT HISPANIC OR LATINO JPN N
#> 47 ASIAN NOT HISPANIC OR LATINO JPN N
#> 48 ASIAN NOT HISPANIC OR LATINO JPN N
#> 49 ASIAN NOT HISPANIC OR LATINO JPN N
#> 50 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO RUS N
#> 51 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO RUS N
#> 52 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO RUS N
#> 53 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO RUS N
#> 54 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO RUS N
#> 55 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO RUS N
#> 56 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO RUS N
#> 57 ASIAN NOT HISPANIC OR LATINO RUS N
#> 58 ASIAN NOT HISPANIC OR LATINO RUS N
#> 59 ASIAN NOT HISPANIC OR LATINO RUS N
#> 60 ASIAN NOT HISPANIC OR LATINO RUS N
#> 61 ASIAN NOT HISPANIC OR LATINO RUS N
#> 62 ASIAN NOT HISPANIC OR LATINO RUS N
#> 63 ASIAN NOT HISPANIC OR LATINO RUS N
#> 64 AMERICAN INDIAN OR ALASKA NATIVE NOT HISPANIC OR LATINO USA N
#> 65 AMERICAN INDIAN OR ALASKA NATIVE NOT HISPANIC OR LATINO USA N
#> 66 AMERICAN INDIAN OR ALASKA NATIVE NOT HISPANIC OR LATINO USA N
#> 67 AMERICAN INDIAN OR ALASKA NATIVE NOT HISPANIC OR LATINO USA N
#> 68 AMERICAN INDIAN OR ALASKA NATIVE NOT HISPANIC OR LATINO USA N
#> 69 AMERICAN INDIAN OR ALASKA NATIVE NOT HISPANIC OR LATINO USA N
#> 70 AMERICAN INDIAN OR ALASKA NATIVE NOT HISPANIC OR LATINO USA N
#> INVID INVNAM ARM ARMCD ACTARM ACTARMCD
#> 1 INV ID BRA-1 Dr. BRA-1 Doe C: Combination ARM C C: Combination ARM C
#> 2 INV ID BRA-1 Dr. BRA-1 Doe C: Combination ARM C C: Combination ARM C
#> 3 INV ID BRA-1 Dr. BRA-1 Doe C: Combination ARM C C: Combination ARM C
#> 4 INV ID BRA-1 Dr. BRA-1 Doe C: Combination ARM C C: Combination ARM C
#> 5 INV ID BRA-1 Dr. BRA-1 Doe C: Combination ARM C C: Combination ARM C
#> 6 INV ID BRA-1 Dr. BRA-1 Doe C: Combination ARM C C: Combination ARM C
#> 7 INV ID BRA-1 Dr. BRA-1 Doe C: Combination ARM C C: Combination ARM C
#> 8 INV ID BRA-9 Dr. BRA-9 Doe A: Drug X ARM A A: Drug X ARM A
#> 9 INV ID BRA-9 Dr. BRA-9 Doe A: Drug X ARM A A: Drug X ARM A
#> 10 INV ID BRA-9 Dr. BRA-9 Doe A: Drug X ARM A A: Drug X ARM A
#> 11 INV ID BRA-9 Dr. BRA-9 Doe A: Drug X ARM A A: Drug X ARM A
#> 12 INV ID BRA-9 Dr. BRA-9 Doe A: Drug X ARM A A: Drug X ARM A
#> 13 INV ID BRA-9 Dr. BRA-9 Doe A: Drug X ARM A A: Drug X ARM A
#> 14 INV ID BRA-9 Dr. BRA-9 Doe A: Drug X ARM A A: Drug X ARM A
#> 15 INV ID CHN-11 Dr. CHN-11 Doe C: Combination ARM C C: Combination ARM C
#> 16 INV ID CHN-11 Dr. CHN-11 Doe C: Combination ARM C C: Combination ARM C
#> 17 INV ID CHN-11 Dr. CHN-11 Doe C: Combination ARM C C: Combination ARM C
#> 18 INV ID CHN-11 Dr. CHN-11 Doe C: Combination ARM C C: Combination ARM C
#> 19 INV ID CHN-11 Dr. CHN-11 Doe C: Combination ARM C C: Combination ARM C
#> 20 INV ID CHN-11 Dr. CHN-11 Doe C: Combination ARM C C: Combination ARM C
#> 21 INV ID CHN-11 Dr. CHN-11 Doe C: Combination ARM C C: Combination ARM C
#> 22 INV ID CHN-11 Dr. CHN-11 Doe A: Drug X ARM A A: Drug X ARM A
#> 23 INV ID CHN-11 Dr. CHN-11 Doe A: Drug X ARM A A: Drug X ARM A
#> 24 INV ID CHN-11 Dr. CHN-11 Doe A: Drug X ARM A A: Drug X ARM A
#> 25 INV ID CHN-11 Dr. CHN-11 Doe A: Drug X ARM A A: Drug X ARM A
#> 26 INV ID CHN-11 Dr. CHN-11 Doe A: Drug X ARM A A: Drug X ARM A
#> 27 INV ID CHN-11 Dr. CHN-11 Doe A: Drug X ARM A A: Drug X ARM A
#> 28 INV ID CHN-11 Dr. CHN-11 Doe A: Drug X ARM A A: Drug X ARM A
#> 29 INV ID CHN-3 Dr. CHN-3 Doe B: Placebo ARM B B: Placebo ARM B
#> 30 INV ID CHN-3 Dr. CHN-3 Doe B: Placebo ARM B B: Placebo ARM B
#> 31 INV ID CHN-3 Dr. CHN-3 Doe B: Placebo ARM B B: Placebo ARM B
#> 32 INV ID CHN-3 Dr. CHN-3 Doe B: Placebo ARM B B: Placebo ARM B
#> 33 INV ID CHN-3 Dr. CHN-3 Doe B: Placebo ARM B B: Placebo ARM B
#> 34 INV ID CHN-3 Dr. CHN-3 Doe B: Placebo ARM B B: Placebo ARM B
#> 35 INV ID CHN-3 Dr. CHN-3 Doe B: Placebo ARM B B: Placebo ARM B
#> 36 INV ID CHN-3 Dr. CHN-3 Doe A: Drug X ARM A A: Drug X ARM A
#> 37 INV ID CHN-3 Dr. CHN-3 Doe A: Drug X ARM A A: Drug X ARM A
#> 38 INV ID CHN-3 Dr. CHN-3 Doe A: Drug X ARM A A: Drug X ARM A
#> 39 INV ID CHN-3 Dr. CHN-3 Doe A: Drug X ARM A A: Drug X ARM A
#> 40 INV ID CHN-3 Dr. CHN-3 Doe A: Drug X ARM A A: Drug X ARM A
#> 41 INV ID CHN-3 Dr. CHN-3 Doe A: Drug X ARM A A: Drug X ARM A
#> 42 INV ID CHN-3 Dr. CHN-3 Doe A: Drug X ARM A A: Drug X ARM A
#> 43 INV ID JPN-4 Dr. JPN-4 Doe A: Drug X ARM A A: Drug X ARM A
#> 44 INV ID JPN-4 Dr. JPN-4 Doe A: Drug X ARM A A: Drug X ARM A
#> 45 INV ID JPN-4 Dr. JPN-4 Doe A: Drug X ARM A A: Drug X ARM A
#> 46 INV ID JPN-4 Dr. JPN-4 Doe A: Drug X ARM A A: Drug X ARM A
#> 47 INV ID JPN-4 Dr. JPN-4 Doe A: Drug X ARM A A: Drug X ARM A
#> 48 INV ID JPN-4 Dr. JPN-4 Doe A: Drug X ARM A A: Drug X ARM A
#> 49 INV ID JPN-4 Dr. JPN-4 Doe A: Drug X ARM A A: Drug X ARM A
#> 50 INV ID RUS-1 Dr. RUS-1 Doe B: Placebo ARM B B: Placebo ARM B
#> 51 INV ID RUS-1 Dr. RUS-1 Doe B: Placebo ARM B B: Placebo ARM B
#> 52 INV ID RUS-1 Dr. RUS-1 Doe B: Placebo ARM B B: Placebo ARM B
#> 53 INV ID RUS-1 Dr. RUS-1 Doe B: Placebo ARM B B: Placebo ARM B
#> 54 INV ID RUS-1 Dr. RUS-1 Doe B: Placebo ARM B B: Placebo ARM B
#> 55 INV ID RUS-1 Dr. RUS-1 Doe B: Placebo ARM B B: Placebo ARM B
#> 56 INV ID RUS-1 Dr. RUS-1 Doe B: Placebo ARM B B: Placebo ARM B
#> 57 INV ID RUS-1 Dr. RUS-1 Doe A: Drug X ARM A A: Drug X ARM A
#> 58 INV ID RUS-1 Dr. RUS-1 Doe A: Drug X ARM A A: Drug X ARM A
#> 59 INV ID RUS-1 Dr. RUS-1 Doe A: Drug X ARM A A: Drug X ARM A
#> 60 INV ID RUS-1 Dr. RUS-1 Doe A: Drug X ARM A A: Drug X ARM A
#> 61 INV ID RUS-1 Dr. RUS-1 Doe A: Drug X ARM A A: Drug X ARM A
#> 62 INV ID RUS-1 Dr. RUS-1 Doe A: Drug X ARM A A: Drug X ARM A
#> 63 INV ID RUS-1 Dr. RUS-1 Doe A: Drug X ARM A A: Drug X ARM A
#> 64 INV ID USA-13 Dr. USA-13 Doe A: Drug X ARM A A: Drug X ARM A
#> 65 INV ID USA-13 Dr. USA-13 Doe A: Drug X ARM A A: Drug X ARM A
#> 66 INV ID USA-13 Dr. USA-13 Doe A: Drug X ARM A A: Drug X ARM A
#> 67 INV ID USA-13 Dr. USA-13 Doe A: Drug X ARM A A: Drug X ARM A
#> 68 INV ID USA-13 Dr. USA-13 Doe A: Drug X ARM A A: Drug X ARM A
#> 69 INV ID USA-13 Dr. USA-13 Doe A: Drug X ARM A A: Drug X ARM A
#> 70 INV ID USA-13 Dr. USA-13 Doe A: Drug X ARM A A: Drug X ARM A
#> TRT01P TRT01A TRT02P TRT02A REGION1
#> 1 C: Combination C: Combination A: Drug X C: Combination South America
#> 2 C: Combination C: Combination A: Drug X C: Combination South America
#> 3 C: Combination C: Combination A: Drug X C: Combination South America
#> 4 C: Combination C: Combination A: Drug X C: Combination South America
#> 5 C: Combination C: Combination A: Drug X C: Combination South America
#> 6 C: Combination C: Combination A: Drug X C: Combination South America
#> 7 C: Combination C: Combination A: Drug X C: Combination South America
#> 8 A: Drug X A: Drug X A: Drug X A: Drug X South America
#> 9 A: Drug X A: Drug X A: Drug X A: Drug X South America
#> 10 A: Drug X A: Drug X A: Drug X A: Drug X South America
#> 11 A: Drug X A: Drug X A: Drug X A: Drug X South America
#> 12 A: Drug X A: Drug X A: Drug X A: Drug X South America
#> 13 A: Drug X A: Drug X A: Drug X A: Drug X South America
#> 14 A: Drug X A: Drug X A: Drug X A: Drug X South America
#> 15 C: Combination C: Combination B: Placebo B: Placebo Asia
#> 16 C: Combination C: Combination B: Placebo B: Placebo Asia
#> 17 C: Combination C: Combination B: Placebo B: Placebo Asia
#> 18 C: Combination C: Combination B: Placebo B: Placebo Asia
#> 19 C: Combination C: Combination B: Placebo B: Placebo Asia
#> 20 C: Combination C: Combination B: Placebo B: Placebo Asia
#> 21 C: Combination C: Combination B: Placebo B: Placebo Asia
#> 22 A: Drug X A: Drug X A: Drug X A: Drug X Asia
#> 23 A: Drug X A: Drug X A: Drug X A: Drug X Asia
#> 24 A: Drug X A: Drug X A: Drug X A: Drug X Asia
#> 25 A: Drug X A: Drug X A: Drug X A: Drug X Asia
#> 26 A: Drug X A: Drug X A: Drug X A: Drug X Asia
#> 27 A: Drug X A: Drug X A: Drug X A: Drug X Asia
#> 28 A: Drug X A: Drug X A: Drug X A: Drug X Asia
#> 29 B: Placebo B: Placebo A: Drug X A: Drug X Asia
#> 30 B: Placebo B: Placebo A: Drug X A: Drug X Asia
#> 31 B: Placebo B: Placebo A: Drug X A: Drug X Asia
#> 32 B: Placebo B: Placebo A: Drug X A: Drug X Asia
#> 33 B: Placebo B: Placebo A: Drug X A: Drug X Asia
#> 34 B: Placebo B: Placebo A: Drug X A: Drug X Asia
#> 35 B: Placebo B: Placebo A: Drug X A: Drug X Asia
#> 36 A: Drug X A: Drug X A: Drug X C: Combination Asia
#> 37 A: Drug X A: Drug X A: Drug X C: Combination Asia
#> 38 A: Drug X A: Drug X A: Drug X C: Combination Asia
#> 39 A: Drug X A: Drug X A: Drug X C: Combination Asia
#> 40 A: Drug X A: Drug X A: Drug X C: Combination Asia
#> 41 A: Drug X A: Drug X A: Drug X C: Combination Asia
#> 42 A: Drug X A: Drug X A: Drug X C: Combination Asia
#> 43 A: Drug X A: Drug X C: Combination B: Placebo Asia
#> 44 A: Drug X A: Drug X C: Combination B: Placebo Asia
#> 45 A: Drug X A: Drug X C: Combination B: Placebo Asia
#> 46 A: Drug X A: Drug X C: Combination B: Placebo Asia
#> 47 A: Drug X A: Drug X C: Combination B: Placebo Asia
#> 48 A: Drug X A: Drug X C: Combination B: Placebo Asia
#> 49 A: Drug X A: Drug X C: Combination B: Placebo Asia
#> 50 B: Placebo B: Placebo A: Drug X A: Drug X Eurasia
#> 51 B: Placebo B: Placebo A: Drug X A: Drug X Eurasia
#> 52 B: Placebo B: Placebo A: Drug X A: Drug X Eurasia
#> 53 B: Placebo B: Placebo A: Drug X A: Drug X Eurasia
#> 54 B: Placebo B: Placebo A: Drug X A: Drug X Eurasia
#> 55 B: Placebo B: Placebo A: Drug X A: Drug X Eurasia
#> 56 B: Placebo B: Placebo A: Drug X A: Drug X Eurasia
#> 57 A: Drug X A: Drug X C: Combination A: Drug X Eurasia
#> 58 A: Drug X A: Drug X C: Combination A: Drug X Eurasia
#> 59 A: Drug X A: Drug X C: Combination A: Drug X Eurasia
#> 60 A: Drug X A: Drug X C: Combination A: Drug X Eurasia
#> 61 A: Drug X A: Drug X C: Combination A: Drug X Eurasia
#> 62 A: Drug X A: Drug X C: Combination A: Drug X Eurasia
#> 63 A: Drug X A: Drug X C: Combination A: Drug X Eurasia
#> 64 A: Drug X A: Drug X B: Placebo A: Drug X North America
#> 65 A: Drug X A: Drug X B: Placebo A: Drug X North America
#> 66 A: Drug X A: Drug X B: Placebo A: Drug X North America
#> 67 A: Drug X A: Drug X B: Placebo A: Drug X North America
#> 68 A: Drug X A: Drug X B: Placebo A: Drug X North America
#> 69 A: Drug X A: Drug X B: Placebo A: Drug X North America
#> 70 A: Drug X A: Drug X B: Placebo A: Drug X North America
#> STRATA1 STRATA2 BMRKR1 BMRKR2 ITTFL SAFFL BMEASIFL BEP01FL AEWITHFL
#> 1 A S1 6.922043 HIGH Y Y Y N N
#> 2 A S1 6.922043 HIGH Y Y Y N N
#> 3 A S1 6.922043 HIGH Y Y Y N N
#> 4 A S1 6.922043 HIGH Y Y Y N N
#> 5 A S1 6.922043 HIGH Y Y Y N N
#> 6 A S1 6.922043 HIGH Y Y Y N N
#> 7 A S1 6.922043 HIGH Y Y Y N N
#> 8 B S2 11.277028 MEDIUM Y Y Y Y N
#> 9 B S2 11.277028 MEDIUM Y Y Y Y N
#> 10 B S2 11.277028 MEDIUM Y Y Y Y N
#> 11 B S2 11.277028 MEDIUM Y Y Y Y N
#> 12 B S2 11.277028 MEDIUM Y Y Y Y N
#> 13 B S2 11.277028 MEDIUM Y Y Y Y N
#> 14 B S2 11.277028 MEDIUM Y Y Y Y N
#> 15 B S1 8.926907 LOW Y Y N N N
#> 16 B S1 8.926907 LOW Y Y N N N
#> 17 B S1 8.926907 LOW Y Y N N N
#> 18 B S1 8.926907 LOW Y Y N N N
#> 19 B S1 8.926907 LOW Y Y N N N
#> 20 B S1 8.926907 LOW Y Y N N N
#> 21 B S1 8.926907 LOW Y Y N N N
#> 22 C S2 4.084350 HIGH Y Y Y Y N
#> 23 C S2 4.084350 HIGH Y Y Y Y N
#> 24 C S2 4.084350 HIGH Y Y Y Y N
#> 25 C S2 4.084350 HIGH Y Y Y Y N
#> 26 C S2 4.084350 HIGH Y Y Y Y N
#> 27 C S2 4.084350 HIGH Y Y Y Y N
#> 28 C S2 4.084350 HIGH Y Y Y Y N
#> 29 A S1 1.777905 LOW Y Y N Y N
#> 30 A S1 1.777905 LOW Y Y N Y N
#> 31 A S1 1.777905 LOW Y Y N Y N
#> 32 A S1 1.777905 LOW Y Y N Y N
#> 33 A S1 1.777905 LOW Y Y N Y N
#> 34 A S1 1.777905 LOW Y Y N Y N
#> 35 A S1 1.777905 LOW Y Y N Y N
#> 36 A S2 2.619796 LOW Y Y Y N N
#> 37 A S2 2.619796 LOW Y Y Y N N
#> 38 A S2 2.619796 LOW Y Y Y N N
#> 39 A S2 2.619796 LOW Y Y Y N N
#> 40 A S2 2.619796 LOW Y Y Y N N
#> 41 A S2 2.619796 LOW Y Y Y N N
#> 42 A S2 2.619796 LOW Y Y Y N N
#> 43 B S1 7.459420 MEDIUM Y Y Y N N
#> 44 B S1 7.459420 MEDIUM Y Y Y N N
#> 45 B S1 7.459420 MEDIUM Y Y Y N N
#> 46 B S1 7.459420 MEDIUM Y Y Y N N
#> 47 B S1 7.459420 MEDIUM Y Y Y N N
#> 48 B S1 7.459420 MEDIUM Y Y Y N N
#> 49 B S1 7.459420 MEDIUM Y Y Y N N
#> 50 A S1 9.952892 MEDIUM Y Y Y N N
#> 51 A S1 9.952892 MEDIUM Y Y Y N N
#> 52 A S1 9.952892 MEDIUM Y Y Y N N
#> 53 A S1 9.952892 MEDIUM Y Y Y N N
#> 54 A S1 9.952892 MEDIUM Y Y Y N N
#> 55 A S1 9.952892 MEDIUM Y Y Y N N
#> 56 A S1 9.952892 MEDIUM Y Y Y N N
#> 57 B S1 9.342782 MEDIUM Y Y N N N
#> 58 B S1 9.342782 MEDIUM Y Y N N N
#> 59 B S1 9.342782 MEDIUM Y Y N N N
#> 60 B S1 9.342782 MEDIUM Y Y N N N
#> 61 B S1 9.342782 MEDIUM Y Y N N N
#> 62 B S1 9.342782 MEDIUM Y Y N N N
#> 63 B S1 9.342782 MEDIUM Y Y N N N
#> 64 C S1 7.254058 LOW Y Y Y N N
#> 65 C S1 7.254058 LOW Y Y Y N N
#> 66 C S1 7.254058 LOW Y Y Y N N
#> 67 C S1 7.254058 LOW Y Y Y N N
#> 68 C S1 7.254058 LOW Y Y Y N N
#> 69 C S1 7.254058 LOW Y Y Y N N
#> 70 C S1 7.254058 LOW Y Y Y N N
#> RANDDT TRTSDTM TRTEDTM TRT01SDTM
#> 1 2021-01-17 2021-01-17 22:43:53 2024-01-18 16:43:53 2021-01-17 22:43:53
#> 2 2021-01-17 2021-01-17 22:43:53 2024-01-18 16:43:53 2021-01-17 22:43:53
#> 3 2021-01-17 2021-01-17 22:43:53 2024-01-18 16:43:53 2021-01-17 22:43:53
#> 4 2021-01-17 2021-01-17 22:43:53 2024-01-18 16:43:53 2021-01-17 22:43:53
#> 5 2021-01-17 2021-01-17 22:43:53 2024-01-18 16:43:53 2021-01-17 22:43:53
#> 6 2021-01-17 2021-01-17 22:43:53 2024-01-18 16:43:53 2021-01-17 22:43:53
#> 7 2021-01-17 2021-01-17 22:43:53 2024-01-18 16:43:53 2021-01-17 22:43:53
#> 8 2020-01-18 2020-01-21 10:19:08 2021-10-16 19:37:36 2020-01-21 10:19:08
#> 9 2020-01-18 2020-01-21 10:19:08 2021-10-16 19:37:36 2020-01-21 10:19:08
#> 10 2020-01-18 2020-01-21 10:19:08 2021-10-16 19:37:36 2020-01-21 10:19:08
#> 11 2020-01-18 2020-01-21 10:19:08 2021-10-16 19:37:36 2020-01-21 10:19:08
#> 12 2020-01-18 2020-01-21 10:19:08 2021-10-16 19:37:36 2020-01-21 10:19:08
#> 13 2020-01-18 2020-01-21 10:19:08 2021-10-16 19:37:36 2020-01-21 10:19:08
#> 14 2020-01-18 2020-01-21 10:19:08 2021-10-16 19:37:36 2020-01-21 10:19:08
#> 15 2020-04-29 2020-05-02 02:28:45 2021-09-08 20:09:38 2020-05-02 02:28:45
#> 16 2020-04-29 2020-05-02 02:28:45 2021-09-08 20:09:38 2020-05-02 02:28:45
#> 17 2020-04-29 2020-05-02 02:28:45 2021-09-08 20:09:38 2020-05-02 02:28:45
#> 18 2020-04-29 2020-05-02 02:28:45 2021-09-08 20:09:38 2020-05-02 02:28:45
#> 19 2020-04-29 2020-05-02 02:28:45 2021-09-08 20:09:38 2020-05-02 02:28:45
#> 20 2020-04-29 2020-05-02 02:28:45 2021-09-08 20:09:38 2020-05-02 02:28:45
#> 21 2020-04-29 2020-05-02 02:28:45 2021-09-08 20:09:38 2020-05-02 02:28:45
#> 22 2020-02-23 2020-02-26 18:15:59 <NA> 2020-02-26 18:15:59
#> 23 2020-02-23 2020-02-26 18:15:59 <NA> 2020-02-26 18:15:59
#> 24 2020-02-23 2020-02-26 18:15:59 <NA> 2020-02-26 18:15:59
#> 25 2020-02-23 2020-02-26 18:15:59 <NA> 2020-02-26 18:15:59
#> 26 2020-02-23 2020-02-26 18:15:59 <NA> 2020-02-26 18:15:59
#> 27 2020-02-23 2020-02-26 18:15:59 <NA> 2020-02-26 18:15:59
#> 28 2020-02-23 2020-02-26 18:15:59 <NA> 2020-02-26 18:15:59
#> 29 2019-03-24 2019-03-28 12:07:16 2022-03-28 06:07:16 2019-03-28 12:07:16
#> 30 2019-03-24 2019-03-28 12:07:16 2022-03-28 06:07:16 2019-03-28 12:07:16
#> 31 2019-03-24 2019-03-28 12:07:16 2022-03-28 06:07:16 2019-03-28 12:07:16
#> 32 2019-03-24 2019-03-28 12:07:16 2022-03-28 06:07:16 2019-03-28 12:07:16
#> 33 2019-03-24 2019-03-28 12:07:16 2022-03-28 06:07:16 2019-03-28 12:07:16
#> 34 2019-03-24 2019-03-28 12:07:16 2022-03-28 06:07:16 2019-03-28 12:07:16
#> 35 2019-03-24 2019-03-28 12:07:16 2022-03-28 06:07:16 2019-03-28 12:07:16
#> 36 2020-06-24 2020-06-27 04:48:00 2023-06-27 22:48:00 2020-06-27 04:48:00
#> 37 2020-06-24 2020-06-27 04:48:00 2023-06-27 22:48:00 2020-06-27 04:48:00
#> 38 2020-06-24 2020-06-27 04:48:00 2023-06-27 22:48:00 2020-06-27 04:48:00
#> 39 2020-06-24 2020-06-27 04:48:00 2023-06-27 22:48:00 2020-06-27 04:48:00
#> 40 2020-06-24 2020-06-27 04:48:00 2023-06-27 22:48:00 2020-06-27 04:48:00
#> 41 2020-06-24 2020-06-27 04:48:00 2023-06-27 22:48:00 2020-06-27 04:48:00
#> 42 2020-06-24 2020-06-27 04:48:00 2023-06-27 22:48:00 2020-06-27 04:48:00
#> 43 2019-09-22 2019-09-22 02:25:18 2022-09-21 20:25:18 2019-09-22 02:25:18
#> 44 2019-09-22 2019-09-22 02:25:18 2022-09-21 20:25:18 2019-09-22 02:25:18
#> 45 2019-09-22 2019-09-22 02:25:18 2022-09-21 20:25:18 2019-09-22 02:25:18
#> 46 2019-09-22 2019-09-22 02:25:18 2022-09-21 20:25:18 2019-09-22 02:25:18
#> 47 2019-09-22 2019-09-22 02:25:18 2022-09-21 20:25:18 2019-09-22 02:25:18
#> 48 2019-09-22 2019-09-22 02:25:18 2022-09-21 20:25:18 2019-09-22 02:25:18
#> 49 2019-09-22 2019-09-22 02:25:18 2022-09-21 20:25:18 2019-09-22 02:25:18
#> 50 2020-08-27 2020-08-28 20:42:09 2022-01-23 08:46:48 2020-08-28 20:42:09
#> 51 2020-08-27 2020-08-28 20:42:09 2022-01-23 08:46:48 2020-08-28 20:42:09
#> 52 2020-08-27 2020-08-28 20:42:09 2022-01-23 08:46:48 2020-08-28 20:42:09
#> 53 2020-08-27 2020-08-28 20:42:09 2022-01-23 08:46:48 2020-08-28 20:42:09
#> 54 2020-08-27 2020-08-28 20:42:09 2022-01-23 08:46:48 2020-08-28 20:42:09
#> 55 2020-08-27 2020-08-28 20:42:09 2022-01-23 08:46:48 2020-08-28 20:42:09
#> 56 2020-08-27 2020-08-28 20:42:09 2022-01-23 08:46:48 2020-08-28 20:42:09
#> 57 2020-10-24 2020-10-26 22:16:26 2023-10-27 16:16:26 2020-10-26 22:16:26
#> 58 2020-10-24 2020-10-26 22:16:26 2023-10-27 16:16:26 2020-10-26 22:16:26
#> 59 2020-10-24 2020-10-26 22:16:26 2023-10-27 16:16:26 2020-10-26 22:16:26
#> 60 2020-10-24 2020-10-26 22:16:26 2023-10-27 16:16:26 2020-10-26 22:16:26
#> 61 2020-10-24 2020-10-26 22:16:26 2023-10-27 16:16:26 2020-10-26 22:16:26
#> 62 2020-10-24 2020-10-26 22:16:26 2023-10-27 16:16:26 2020-10-26 22:16:26
#> 63 2020-10-24 2020-10-26 22:16:26 2023-10-27 16:16:26 2020-10-26 22:16:26
#> 64 2019-10-16 2019-10-17 17:56:02 2022-10-17 11:56:02 2019-10-17 17:56:02
#> 65 2019-10-16 2019-10-17 17:56:02 2022-10-17 11:56:02 2019-10-17 17:56:02
#> 66 2019-10-16 2019-10-17 17:56:02 2022-10-17 11:56:02 2019-10-17 17:56:02
#> 67 2019-10-16 2019-10-17 17:56:02 2022-10-17 11:56:02 2019-10-17 17:56:02
#> 68 2019-10-16 2019-10-17 17:56:02 2022-10-17 11:56:02 2019-10-17 17:56:02
#> 69 2019-10-16 2019-10-17 17:56:02 2022-10-17 11:56:02 2019-10-17 17:56:02
#> 70 2019-10-16 2019-10-17 17:56:02 2022-10-17 11:56:02 2019-10-17 17:56:02
#> TRT01EDTM TRT02SDTM TRT02EDTM
#> 1 2023-01-18 10:43:53 2023-01-18 10:43:53 2024-01-18 16:43:53
#> 2 2023-01-18 10:43:53 2023-01-18 10:43:53 2024-01-18 16:43:53
#> 3 2023-01-18 10:43:53 2023-01-18 10:43:53 2024-01-18 16:43:53
#> 4 2023-01-18 10:43:53 2023-01-18 10:43:53 2024-01-18 16:43:53
#> 5 2023-01-18 10:43:53 2023-01-18 10:43:53 2024-01-18 16:43:53
#> 6 2023-01-18 10:43:53 2023-01-18 10:43:53 2024-01-18 16:43:53
#> 7 2023-01-18 10:43:53 2023-01-18 10:43:53 2024-01-18 16:43:53
#> 8 2020-10-16 13:37:36 2020-10-16 13:37:36 2021-10-16 19:37:36
#> 9 2020-10-16 13:37:36 2020-10-16 13:37:36 2021-10-16 19:37:36
#> 10 2020-10-16 13:37:36 2020-10-16 13:37:36 2021-10-16 19:37:36
#> 11 2020-10-16 13:37:36 2020-10-16 13:37:36 2021-10-16 19:37:36
#> 12 2020-10-16 13:37:36 2020-10-16 13:37:36 2021-10-16 19:37:36
#> 13 2020-10-16 13:37:36 2020-10-16 13:37:36 2021-10-16 19:37:36
#> 14 2020-10-16 13:37:36 2020-10-16 13:37:36 2021-10-16 19:37:36
#> 15 2020-09-08 14:09:38 2020-09-08 14:09:38 2021-09-08 20:09:38
#> 16 2020-09-08 14:09:38 2020-09-08 14:09:38 2021-09-08 20:09:38
#> 17 2020-09-08 14:09:38 2020-09-08 14:09:38 2021-09-08 20:09:38
#> 18 2020-09-08 14:09:38 2020-09-08 14:09:38 2021-09-08 20:09:38
#> 19 2020-09-08 14:09:38 2020-09-08 14:09:38 2021-09-08 20:09:38
#> 20 2020-09-08 14:09:38 2020-09-08 14:09:38 2021-09-08 20:09:38
#> 21 2020-09-08 14:09:38 2020-09-08 14:09:38 2021-09-08 20:09:38
#> 22 <NA> <NA> <NA>
#> 23 <NA> <NA> <NA>
#> 24 <NA> <NA> <NA>
#> 25 <NA> <NA> <NA>
#> 26 <NA> <NA> <NA>
#> 27 <NA> <NA> <NA>
#> 28 <NA> <NA> <NA>
#> 29 2021-03-28 00:07:16 2021-03-28 00:07:16 2022-03-28 06:07:16
#> 30 2021-03-28 00:07:16 2021-03-28 00:07:16 2022-03-28 06:07:16
#> 31 2021-03-28 00:07:16 2021-03-28 00:07:16 2022-03-28 06:07:16
#> 32 2021-03-28 00:07:16 2021-03-28 00:07:16 2022-03-28 06:07:16
#> 33 2021-03-28 00:07:16 2021-03-28 00:07:16 2022-03-28 06:07:16
#> 34 2021-03-28 00:07:16 2021-03-28 00:07:16 2022-03-28 06:07:16
#> 35 2021-03-28 00:07:16 2021-03-28 00:07:16 2022-03-28 06:07:16
#> 36 2022-06-27 16:48:00 2022-06-27 16:48:00 2023-06-27 22:48:00
#> 37 2022-06-27 16:48:00 2022-06-27 16:48:00 2023-06-27 22:48:00
#> 38 2022-06-27 16:48:00 2022-06-27 16:48:00 2023-06-27 22:48:00
#> 39 2022-06-27 16:48:00 2022-06-27 16:48:00 2023-06-27 22:48:00
#> 40 2022-06-27 16:48:00 2022-06-27 16:48:00 2023-06-27 22:48:00
#> 41 2022-06-27 16:48:00 2022-06-27 16:48:00 2023-06-27 22:48:00
#> 42 2022-06-27 16:48:00 2022-06-27 16:48:00 2023-06-27 22:48:00
#> 43 2021-09-21 14:25:18 2021-09-21 14:25:18 2022-09-21 20:25:18
#> 44 2021-09-21 14:25:18 2021-09-21 14:25:18 2022-09-21 20:25:18
#> 45 2021-09-21 14:25:18 2021-09-21 14:25:18 2022-09-21 20:25:18
#> 46 2021-09-21 14:25:18 2021-09-21 14:25:18 2022-09-21 20:25:18
#> 47 2021-09-21 14:25:18 2021-09-21 14:25:18 2022-09-21 20:25:18
#> 48 2021-09-21 14:25:18 2021-09-21 14:25:18 2022-09-21 20:25:18
#> 49 2021-09-21 14:25:18 2021-09-21 14:25:18 2022-09-21 20:25:18
#> 50 2021-01-23 02:46:48 2021-01-23 02:46:48 2022-01-23 08:46:48
#> 51 2021-01-23 02:46:48 2021-01-23 02:46:48 2022-01-23 08:46:48
#> 52 2021-01-23 02:46:48 2021-01-23 02:46:48 2022-01-23 08:46:48
#> 53 2021-01-23 02:46:48 2021-01-23 02:46:48 2022-01-23 08:46:48
#> 54 2021-01-23 02:46:48 2021-01-23 02:46:48 2022-01-23 08:46:48
#> 55 2021-01-23 02:46:48 2021-01-23 02:46:48 2022-01-23 08:46:48
#> 56 2021-01-23 02:46:48 2021-01-23 02:46:48 2022-01-23 08:46:48
#> 57 2022-10-27 10:16:26 2022-10-27 10:16:26 2023-10-27 16:16:26
#> 58 2022-10-27 10:16:26 2022-10-27 10:16:26 2023-10-27 16:16:26
#> 59 2022-10-27 10:16:26 2022-10-27 10:16:26 2023-10-27 16:16:26
#> 60 2022-10-27 10:16:26 2022-10-27 10:16:26 2023-10-27 16:16:26
#> 61 2022-10-27 10:16:26 2022-10-27 10:16:26 2023-10-27 16:16:26
#> 62 2022-10-27 10:16:26 2022-10-27 10:16:26 2023-10-27 16:16:26
#> 63 2022-10-27 10:16:26 2022-10-27 10:16:26 2023-10-27 16:16:26
#> 64 2021-10-17 05:56:02 2021-10-17 05:56:02 2022-10-17 11:56:02
#> 65 2021-10-17 05:56:02 2021-10-17 05:56:02 2022-10-17 11:56:02
#> 66 2021-10-17 05:56:02 2021-10-17 05:56:02 2022-10-17 11:56:02
#> 67 2021-10-17 05:56:02 2021-10-17 05:56:02 2022-10-17 11:56:02
#> 68 2021-10-17 05:56:02 2021-10-17 05:56:02 2022-10-17 11:56:02
#> 69 2021-10-17 05:56:02 2021-10-17 05:56:02 2022-10-17 11:56:02
#> 70 2021-10-17 05:56:02 2021-10-17 05:56:02 2022-10-17 11:56:02
#> AP01SDTM AP01EDTM AP02SDTM
#> 1 2021-01-17 22:43:53 2023-01-18 10:43:53 2023-01-18 10:43:53
#> 2 2021-01-17 22:43:53 2023-01-18 10:43:53 2023-01-18 10:43:53
#> 3 2021-01-17 22:43:53 2023-01-18 10:43:53 2023-01-18 10:43:53
#> 4 2021-01-17 22:43:53 2023-01-18 10:43:53 2023-01-18 10:43:53
#> 5 2021-01-17 22:43:53 2023-01-18 10:43:53 2023-01-18 10:43:53
#> 6 2021-01-17 22:43:53 2023-01-18 10:43:53 2023-01-18 10:43:53
#> 7 2021-01-17 22:43:53 2023-01-18 10:43:53 2023-01-18 10:43:53
#> 8 2020-01-21 10:19:08 2020-10-16 13:37:36 2020-10-16 13:37:36
#> 9 2020-01-21 10:19:08 2020-10-16 13:37:36 2020-10-16 13:37:36
#> 10 2020-01-21 10:19:08 2020-10-16 13:37:36 2020-10-16 13:37:36
#> 11 2020-01-21 10:19:08 2020-10-16 13:37:36 2020-10-16 13:37:36
#> 12 2020-01-21 10:19:08 2020-10-16 13:37:36 2020-10-16 13:37:36
#> 13 2020-01-21 10:19:08 2020-10-16 13:37:36 2020-10-16 13:37:36
#> 14 2020-01-21 10:19:08 2020-10-16 13:37:36 2020-10-16 13:37:36
#> 15 2020-05-02 02:28:45 2020-09-08 14:09:38 2020-09-08 14:09:38
#> 16 2020-05-02 02:28:45 2020-09-08 14:09:38 2020-09-08 14:09:38
#> 17 2020-05-02 02:28:45 2020-09-08 14:09:38 2020-09-08 14:09:38
#> 18 2020-05-02 02:28:45 2020-09-08 14:09:38 2020-09-08 14:09:38
#> 19 2020-05-02 02:28:45 2020-09-08 14:09:38 2020-09-08 14:09:38
#> 20 2020-05-02 02:28:45 2020-09-08 14:09:38 2020-09-08 14:09:38
#> 21 2020-05-02 02:28:45 2020-09-08 14:09:38 2020-09-08 14:09:38
#> 22 2020-02-26 18:15:59 <NA> <NA>
#> 23 2020-02-26 18:15:59 <NA> <NA>
#> 24 2020-02-26 18:15:59 <NA> <NA>
#> 25 2020-02-26 18:15:59 <NA> <NA>
#> 26 2020-02-26 18:15:59 <NA> <NA>
#> 27 2020-02-26 18:15:59 <NA> <NA>
#> 28 2020-02-26 18:15:59 <NA> <NA>
#> 29 2019-03-28 12:07:16 2021-03-28 00:07:16 2021-03-28 00:07:16
#> 30 2019-03-28 12:07:16 2021-03-28 00:07:16 2021-03-28 00:07:16
#> 31 2019-03-28 12:07:16 2021-03-28 00:07:16 2021-03-28 00:07:16
#> 32 2019-03-28 12:07:16 2021-03-28 00:07:16 2021-03-28 00:07:16
#> 33 2019-03-28 12:07:16 2021-03-28 00:07:16 2021-03-28 00:07:16
#> 34 2019-03-28 12:07:16 2021-03-28 00:07:16 2021-03-28 00:07:16
#> 35 2019-03-28 12:07:16 2021-03-28 00:07:16 2021-03-28 00:07:16
#> 36 2020-06-27 04:48:00 2022-06-27 16:48:00 2022-06-27 16:48:00
#> 37 2020-06-27 04:48:00 2022-06-27 16:48:00 2022-06-27 16:48:00
#> 38 2020-06-27 04:48:00 2022-06-27 16:48:00 2022-06-27 16:48:00
#> 39 2020-06-27 04:48:00 2022-06-27 16:48:00 2022-06-27 16:48:00
#> 40 2020-06-27 04:48:00 2022-06-27 16:48:00 2022-06-27 16:48:00
#> 41 2020-06-27 04:48:00 2022-06-27 16:48:00 2022-06-27 16:48:00
#> 42 2020-06-27 04:48:00 2022-06-27 16:48:00 2022-06-27 16:48:00
#> 43 2019-09-22 02:25:18 2021-09-21 14:25:18 2021-09-21 14:25:18
#> 44 2019-09-22 02:25:18 2021-09-21 14:25:18 2021-09-21 14:25:18
#> 45 2019-09-22 02:25:18 2021-09-21 14:25:18 2021-09-21 14:25:18
#> 46 2019-09-22 02:25:18 2021-09-21 14:25:18 2021-09-21 14:25:18
#> 47 2019-09-22 02:25:18 2021-09-21 14:25:18 2021-09-21 14:25:18
#> 48 2019-09-22 02:25:18 2021-09-21 14:25:18 2021-09-21 14:25:18
#> 49 2019-09-22 02:25:18 2021-09-21 14:25:18 2021-09-21 14:25:18
#> 50 2020-08-28 20:42:09 2021-01-23 02:46:48 2021-01-23 02:46:48
#> 51 2020-08-28 20:42:09 2021-01-23 02:46:48 2021-01-23 02:46:48
#> 52 2020-08-28 20:42:09 2021-01-23 02:46:48 2021-01-23 02:46:48
#> 53 2020-08-28 20:42:09 2021-01-23 02:46:48 2021-01-23 02:46:48
#> 54 2020-08-28 20:42:09 2021-01-23 02:46:48 2021-01-23 02:46:48
#> 55 2020-08-28 20:42:09 2021-01-23 02:46:48 2021-01-23 02:46:48
#> 56 2020-08-28 20:42:09 2021-01-23 02:46:48 2021-01-23 02:46:48
#> 57 2020-10-26 22:16:26 2022-10-27 10:16:26 2022-10-27 10:16:26
#> 58 2020-10-26 22:16:26 2022-10-27 10:16:26 2022-10-27 10:16:26
#> 59 2020-10-26 22:16:26 2022-10-27 10:16:26 2022-10-27 10:16:26
#> 60 2020-10-26 22:16:26 2022-10-27 10:16:26 2022-10-27 10:16:26
#> 61 2020-10-26 22:16:26 2022-10-27 10:16:26 2022-10-27 10:16:26
#> 62 2020-10-26 22:16:26 2022-10-27 10:16:26 2022-10-27 10:16:26
#> 63 2020-10-26 22:16:26 2022-10-27 10:16:26 2022-10-27 10:16:26
#> 64 2019-10-17 17:56:02 2021-10-17 05:56:02 2021-10-17 05:56:02
#> 65 2019-10-17 17:56:02 2021-10-17 05:56:02 2021-10-17 05:56:02
#> 66 2019-10-17 17:56:02 2021-10-17 05:56:02 2021-10-17 05:56:02
#> 67 2019-10-17 17:56:02 2021-10-17 05:56:02 2021-10-17 05:56:02
#> 68 2019-10-17 17:56:02 2021-10-17 05:56:02 2021-10-17 05:56:02
#> 69 2019-10-17 17:56:02 2021-10-17 05:56:02 2021-10-17 05:56:02
#> 70 2019-10-17 17:56:02 2021-10-17 05:56:02 2021-10-17 05:56:02
#> AP02EDTM EOSSTT EOTSTT EOSDT EOSDY DCSREAS
#> 1 2024-01-18 16:43:53 COMPLETED COMPLETED 2024-01-18 1096 <NA>
#> 2 2024-01-18 16:43:53 COMPLETED COMPLETED 2024-01-18 1096 <NA>
#> 3 2024-01-18 16:43:53 COMPLETED COMPLETED 2024-01-18 1096 <NA>
#> 4 2024-01-18 16:43:53 COMPLETED COMPLETED 2024-01-18 1096 <NA>
#> 5 2024-01-18 16:43:53 COMPLETED COMPLETED 2024-01-18 1096 <NA>
#> 6 2024-01-18 16:43:53 COMPLETED COMPLETED 2024-01-18 1096 <NA>
#> 7 2024-01-18 16:43:53 COMPLETED COMPLETED 2024-01-18 1096 <NA>
#> 8 2021-10-16 19:37:36 DISCONTINUED DISCONTINUED 2021-10-16 635 DEATH
#> 9 2021-10-16 19:37:36 DISCONTINUED DISCONTINUED 2021-10-16 635 DEATH
#> 10 2021-10-16 19:37:36 DISCONTINUED DISCONTINUED 2021-10-16 635 DEATH
#> 11 2021-10-16 19:37:36 DISCONTINUED DISCONTINUED 2021-10-16 635 DEATH
#> 12 2021-10-16 19:37:36 DISCONTINUED DISCONTINUED 2021-10-16 635 DEATH
#> 13 2021-10-16 19:37:36 DISCONTINUED DISCONTINUED 2021-10-16 635 DEATH
#> 14 2021-10-16 19:37:36 DISCONTINUED DISCONTINUED 2021-10-16 635 DEATH
#> 15 2021-09-08 20:09:38 DISCONTINUED DISCONTINUED 2021-09-08 495 DEATH
#> 16 2021-09-08 20:09:38 DISCONTINUED DISCONTINUED 2021-09-08 495 DEATH
#> 17 2021-09-08 20:09:38 DISCONTINUED DISCONTINUED 2021-09-08 495 DEATH
#> 18 2021-09-08 20:09:38 DISCONTINUED DISCONTINUED 2021-09-08 495 DEATH
#> 19 2021-09-08 20:09:38 DISCONTINUED DISCONTINUED 2021-09-08 495 DEATH
#> 20 2021-09-08 20:09:38 DISCONTINUED DISCONTINUED 2021-09-08 495 DEATH
#> 21 2021-09-08 20:09:38 DISCONTINUED DISCONTINUED 2021-09-08 495 DEATH
#> 22 <NA> ONGOING ONGOING <NA> NA <NA>
#> 23 <NA> ONGOING ONGOING <NA> NA <NA>
#> 24 <NA> ONGOING ONGOING <NA> NA <NA>
#> 25 <NA> ONGOING ONGOING <NA> NA <NA>
#> 26 <NA> ONGOING ONGOING <NA> NA <NA>
#> 27 <NA> ONGOING ONGOING <NA> NA <NA>
#> 28 <NA> ONGOING ONGOING <NA> NA <NA>
#> 29 2022-03-28 06:07:16 COMPLETED COMPLETED 2022-03-28 1096 <NA>
#> 30 2022-03-28 06:07:16 COMPLETED COMPLETED 2022-03-28 1096 <NA>
#> 31 2022-03-28 06:07:16 COMPLETED COMPLETED 2022-03-28 1096 <NA>
#> 32 2022-03-28 06:07:16 COMPLETED COMPLETED 2022-03-28 1096 <NA>
#> 33 2022-03-28 06:07:16 COMPLETED COMPLETED 2022-03-28 1096 <NA>
#> 34 2022-03-28 06:07:16 COMPLETED COMPLETED 2022-03-28 1096 <NA>
#> 35 2022-03-28 06:07:16 COMPLETED COMPLETED 2022-03-28 1096 <NA>
#> 36 2023-06-27 22:48:00 COMPLETED COMPLETED 2023-06-27 1096 <NA>
#> 37 2023-06-27 22:48:00 COMPLETED COMPLETED 2023-06-27 1096 <NA>
#> 38 2023-06-27 22:48:00 COMPLETED COMPLETED 2023-06-27 1096 <NA>
#> 39 2023-06-27 22:48:00 COMPLETED COMPLETED 2023-06-27 1096 <NA>
#> 40 2023-06-27 22:48:00 COMPLETED COMPLETED 2023-06-27 1096 <NA>
#> 41 2023-06-27 22:48:00 COMPLETED COMPLETED 2023-06-27 1096 <NA>
#> 42 2023-06-27 22:48:00 COMPLETED COMPLETED 2023-06-27 1096 <NA>
#> 43 2022-09-21 20:25:18 COMPLETED COMPLETED 2022-09-21 1096 <NA>
#> 44 2022-09-21 20:25:18 COMPLETED COMPLETED 2022-09-21 1096 <NA>
#> 45 2022-09-21 20:25:18 COMPLETED COMPLETED 2022-09-21 1096 <NA>
#> 46 2022-09-21 20:25:18 COMPLETED COMPLETED 2022-09-21 1096 <NA>
#> 47 2022-09-21 20:25:18 COMPLETED COMPLETED 2022-09-21 1096 <NA>
#> 48 2022-09-21 20:25:18 COMPLETED COMPLETED 2022-09-21 1096 <NA>
#> 49 2022-09-21 20:25:18 COMPLETED COMPLETED 2022-09-21 1096 <NA>
#> 50 2022-01-23 08:46:48 DISCONTINUED DISCONTINUED 2022-01-23 513 ADVERSE EVENT
#> 51 2022-01-23 08:46:48 DISCONTINUED DISCONTINUED 2022-01-23 513 ADVERSE EVENT
#> 52 2022-01-23 08:46:48 DISCONTINUED DISCONTINUED 2022-01-23 513 ADVERSE EVENT
#> 53 2022-01-23 08:46:48 DISCONTINUED DISCONTINUED 2022-01-23 513 ADVERSE EVENT
#> 54 2022-01-23 08:46:48 DISCONTINUED DISCONTINUED 2022-01-23 513 ADVERSE EVENT
#> 55 2022-01-23 08:46:48 DISCONTINUED DISCONTINUED 2022-01-23 513 ADVERSE EVENT
#> 56 2022-01-23 08:46:48 DISCONTINUED DISCONTINUED 2022-01-23 513 ADVERSE EVENT
#> 57 2023-10-27 16:16:26 COMPLETED COMPLETED 2023-10-27 1096 <NA>
#> 58 2023-10-27 16:16:26 COMPLETED COMPLETED 2023-10-27 1096 <NA>
#> 59 2023-10-27 16:16:26 COMPLETED COMPLETED 2023-10-27 1096 <NA>
#> 60 2023-10-27 16:16:26 COMPLETED COMPLETED 2023-10-27 1096 <NA>
#> 61 2023-10-27 16:16:26 COMPLETED COMPLETED 2023-10-27 1096 <NA>
#> 62 2023-10-27 16:16:26 COMPLETED COMPLETED 2023-10-27 1096 <NA>
#> 63 2023-10-27 16:16:26 COMPLETED COMPLETED 2023-10-27 1096 <NA>
#> 64 2022-10-17 11:56:02 COMPLETED COMPLETED 2022-10-17 1096 <NA>
#> 65 2022-10-17 11:56:02 COMPLETED COMPLETED 2022-10-17 1096 <NA>
#> 66 2022-10-17 11:56:02 COMPLETED COMPLETED 2022-10-17 1096 <NA>
#> 67 2022-10-17 11:56:02 COMPLETED COMPLETED 2022-10-17 1096 <NA>
#> 68 2022-10-17 11:56:02 COMPLETED COMPLETED 2022-10-17 1096 <NA>
#> 69 2022-10-17 11:56:02 COMPLETED COMPLETED 2022-10-17 1096 <NA>
#> 70 2022-10-17 11:56:02 COMPLETED COMPLETED 2022-10-17 1096 <NA>
#> DTHDT DTHCAUS DTHCAT LDDTHELD LDDTHGR1
#> 1 <NA> <NA> <NA> NA <NA>
#> 2 <NA> <NA> <NA> NA <NA>
#> 3 <NA> <NA> <NA> NA <NA>
#> 4 <NA> <NA> <NA> NA <NA>
#> 5 <NA> <NA> <NA> NA <NA>
#> 6 <NA> <NA> <NA> NA <NA>
#> 7 <NA> <NA> <NA> NA <NA>
#> 8 2021-11-23 DISEASE PROGRESSION PROGRESSIVE DISEASE 38 >30
#> 9 2021-11-23 DISEASE PROGRESSION PROGRESSIVE DISEASE 38 >30
#> 10 2021-11-23 DISEASE PROGRESSION PROGRESSIVE DISEASE 38 >30
#> 11 2021-11-23 DISEASE PROGRESSION PROGRESSIVE DISEASE 38 >30
#> 12 2021-11-23 DISEASE PROGRESSION PROGRESSIVE DISEASE 38 >30
#> 13 2021-11-23 DISEASE PROGRESSION PROGRESSIVE DISEASE 38 >30
#> 14 2021-11-23 DISEASE PROGRESSION PROGRESSIVE DISEASE 38 >30
#> 15 2021-09-27 ADVERSE EVENT ADVERSE EVENT 19 <=30
#> 16 2021-09-27 ADVERSE EVENT ADVERSE EVENT 19 <=30
#> 17 2021-09-27 ADVERSE EVENT ADVERSE EVENT 19 <=30
#> 18 2021-09-27 ADVERSE EVENT ADVERSE EVENT 19 <=30
#> 19 2021-09-27 ADVERSE EVENT ADVERSE EVENT 19 <=30
#> 20 2021-09-27 ADVERSE EVENT ADVERSE EVENT 19 <=30
#> 21 2021-09-27 ADVERSE EVENT ADVERSE EVENT 19 <=30
#> 22 <NA> <NA> <NA> NA <NA>
#> 23 <NA> <NA> <NA> NA <NA>
#> 24 <NA> <NA> <NA> NA <NA>
#> 25 <NA> <NA> <NA> NA <NA>
#> 26 <NA> <NA> <NA> NA <NA>
#> 27 <NA> <NA> <NA> NA <NA>
#> 28 <NA> <NA> <NA> NA <NA>
#> 29 <NA> <NA> <NA> NA <NA>
#> 30 <NA> <NA> <NA> NA <NA>
#> 31 <NA> <NA> <NA> NA <NA>
#> 32 <NA> <NA> <NA> NA <NA>
#> 33 <NA> <NA> <NA> NA <NA>
#> 34 <NA> <NA> <NA> NA <NA>
#> 35 <NA> <NA> <NA> NA <NA>
#> 36 <NA> <NA> <NA> NA <NA>
#> 37 <NA> <NA> <NA> NA <NA>
#> 38 <NA> <NA> <NA> NA <NA>
#> 39 <NA> <NA> <NA> NA <NA>
#> 40 <NA> <NA> <NA> NA <NA>
#> 41 <NA> <NA> <NA> NA <NA>
#> 42 <NA> <NA> <NA> NA <NA>
#> 43 <NA> <NA> <NA> NA <NA>
#> 44 <NA> <NA> <NA> NA <NA>
#> 45 <NA> <NA> <NA> NA <NA>
#> 46 <NA> <NA> <NA> NA <NA>
#> 47 <NA> <NA> <NA> NA <NA>
#> 48 <NA> <NA> <NA> NA <NA>
#> 49 <NA> <NA> <NA> NA <NA>
#> 50 <NA> <NA> <NA> NA <NA>
#> 51 <NA> <NA> <NA> NA <NA>
#> 52 <NA> <NA> <NA> NA <NA>
#> 53 <NA> <NA> <NA> NA <NA>
#> 54 <NA> <NA> <NA> NA <NA>
#> 55 <NA> <NA> <NA> NA <NA>
#> 56 <NA> <NA> <NA> NA <NA>
#> 57 <NA> <NA> <NA> NA <NA>
#> 58 <NA> <NA> <NA> NA <NA>
#> 59 <NA> <NA> <NA> NA <NA>
#> 60 <NA> <NA> <NA> NA <NA>
#> 61 <NA> <NA> <NA> NA <NA>
#> 62 <NA> <NA> <NA> NA <NA>
#> 63 <NA> <NA> <NA> NA <NA>
#> 64 <NA> <NA> <NA> NA <NA>
#> 65 <NA> <NA> <NA> NA <NA>
#> 66 <NA> <NA> <NA> NA <NA>
#> 67 <NA> <NA> <NA> NA <NA>
#> 68 <NA> <NA> <NA> NA <NA>
#> 69 <NA> <NA> <NA> NA <NA>
#> 70 <NA> <NA> <NA> NA <NA>
#> LSTALVDT DTHADY ADTHAUT AGEGR1 TRTDURD DCSREAS_GRP
#> 1 2024-02-10 NA <NA> <65 1094.7500 <NA>
#> 2 2024-02-10 NA <NA> <65 1094.7500 <NA>
#> 3 2024-02-10 NA <NA> <65 1094.7500 <NA>
#> 4 2024-02-10 NA <NA> <65 1094.7500 <NA>
#> 5 2024-02-10 NA <NA> <65 1094.7500 <NA>
#> 6 2024-02-10 NA <NA> <65 1094.7500 <NA>
#> 7 2024-02-10 NA <NA> <65 1094.7500 <NA>
#> 8 2021-11-23 671 Yes <65 633.3878 Non-Safety
#> 9 2021-11-23 671 Yes <65 633.3878 Non-Safety
#> 10 2021-11-23 671 Yes <65 633.3878 Non-Safety
#> 11 2021-11-23 671 Yes <65 633.3878 Non-Safety
#> 12 2021-11-23 671 Yes <65 633.3878 Non-Safety
#> 13 2021-11-23 671 Yes <65 633.3878 Non-Safety
#> 14 2021-11-23 671 Yes <65 633.3878 Non-Safety
#> 15 2021-09-27 512 Yes <65 493.7367 Non-Safety
#> 16 2021-09-27 512 Yes <65 493.7367 Non-Safety
#> 17 2021-09-27 512 Yes <65 493.7367 Non-Safety
#> 18 2021-09-27 512 Yes <65 493.7367 Non-Safety
#> 19 2021-09-27 512 Yes <65 493.7367 Non-Safety
#> 20 2021-09-27 512 Yes <65 493.7367 Non-Safety
#> 21 2021-09-27 512 Yes <65 493.7367 Non-Safety
#> 22 <NA> NA <NA> <65 NA <NA>
#> 23 <NA> NA <NA> <65 NA <NA>
#> 24 <NA> NA <NA> <65 NA <NA>
#> 25 <NA> NA <NA> <65 NA <NA>
#> 26 <NA> NA <NA> <65 NA <NA>
#> 27 <NA> NA <NA> <65 NA <NA>
#> 28 <NA> NA <NA> <65 NA <NA>
#> 29 2022-04-14 NA <NA> <65 1094.7500 <NA>
#> 30 2022-04-14 NA <NA> <65 1094.7500 <NA>
#> 31 2022-04-14 NA <NA> <65 1094.7500 <NA>
#> 32 2022-04-14 NA <NA> <65 1094.7500 <NA>
#> 33 2022-04-14 NA <NA> <65 1094.7500 <NA>
#> 34 2022-04-14 NA <NA> <65 1094.7500 <NA>
#> 35 2022-04-14 NA <NA> <65 1094.7500 <NA>
#> 36 2023-07-10 NA <NA> <65 1094.7500 <NA>
#> 37 2023-07-10 NA <NA> <65 1094.7500 <NA>
#> 38 2023-07-10 NA <NA> <65 1094.7500 <NA>
#> 39 2023-07-10 NA <NA> <65 1094.7500 <NA>
#> 40 2023-07-10 NA <NA> <65 1094.7500 <NA>
#> 41 2023-07-10 NA <NA> <65 1094.7500 <NA>
#> 42 2023-07-10 NA <NA> <65 1094.7500 <NA>
#> 43 2022-10-09 NA <NA> <65 1094.7500 <NA>
#> 44 2022-10-09 NA <NA> <65 1094.7500 <NA>
#> 45 2022-10-09 NA <NA> <65 1094.7500 <NA>
#> 46 2022-10-09 NA <NA> <65 1094.7500 <NA>
#> 47 2022-10-09 NA <NA> <65 1094.7500 <NA>
#> 48 2022-10-09 NA <NA> <65 1094.7500 <NA>
#> 49 2022-10-09 NA <NA> <65 1094.7500 <NA>
#> 50 2022-02-12 NA <NA> <65 511.5032 Safety
#> 51 2022-02-12 NA <NA> <65 511.5032 Safety
#> 52 2022-02-12 NA <NA> <65 511.5032 Safety
#> 53 2022-02-12 NA <NA> <65 511.5032 Safety
#> 54 2022-02-12 NA <NA> <65 511.5032 Safety
#> 55 2022-02-12 NA <NA> <65 511.5032 Safety
#> 56 2022-02-12 NA <NA> <65 511.5032 Safety
#> 57 2023-11-13 NA <NA> <65 1094.7500 <NA>
#> 58 2023-11-13 NA <NA> <65 1094.7500 <NA>
#> 59 2023-11-13 NA <NA> <65 1094.7500 <NA>
#> 60 2023-11-13 NA <NA> <65 1094.7500 <NA>
#> 61 2023-11-13 NA <NA> <65 1094.7500 <NA>
#> 62 2023-11-13 NA <NA> <65 1094.7500 <NA>
#> 63 2023-11-13 NA <NA> <65 1094.7500 <NA>
#> 64 2022-10-30 NA <NA> <65 1094.7500 <NA>
#> 65 2022-10-30 NA <NA> <65 1094.7500 <NA>
#> 66 2022-10-30 NA <NA> <65 1094.7500 <NA>
#> 67 2022-10-30 NA <NA> <65 1094.7500 <NA>
#> 68 2022-10-30 NA <NA> <65 1094.7500 <NA>
#> 69 2022-10-30 NA <NA> <65 1094.7500 <NA>
#> 70 2022-10-30 NA <NA> <65 1094.7500 <NA>
#> PARAM PARAMCD AVISIT
#> 1 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 2 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 3 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 4 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 5 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 6 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 7 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 8 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 9 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 10 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 11 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 12 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 13 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 14 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 15 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 16 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 17 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 18 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 19 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 20 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 21 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 22 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 23 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 24 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 25 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 26 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 27 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 28 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 29 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 30 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 31 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 32 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 33 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 34 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 35 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 36 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 37 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 38 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 39 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 40 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 41 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 42 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 43 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 44 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 45 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 46 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 47 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 48 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 49 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 50 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 51 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 52 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 53 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 54 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 55 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 56 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 57 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 58 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 59 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 60 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 61 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 62 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 63 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 64 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 65 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 66 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 67 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 68 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 69 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 70 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> AVISITN ADTM ADY DTYPE AVAL AVALC AVALU BASE
#> 1 999 2022-12-07 689 170.92083 170.920832028446 mm 113.2925
#> 2 4 2022-12-20 702 MINIMUM 129.31849 129.318489083911 mm 113.2925
#> 3 -1 2020-10-09 -100 176.74793 176.747928468497 mm 113.2925
#> 4 0 2021-01-17 0 NA <NA> mm 113.2925
#> 5 2 2022-10-21 642 155.21502 155.215022960478 mm 113.2925
#> 6 4 2022-12-20 702 129.31849 129.318489083911 mm 113.2925
#> 7 999 2021-10-16 272 186.12497 186.12497059324 mm 113.2925
#> 8 999 2020-09-07 230 162.83456 162.834559197379 mm 137.2934
#> 9 4 2021-01-03 348 203.88264 203.882642391259 mm 137.2934
#> 10 999 2021-08-17 574 177.21001 177.210013002554 mm 137.2934
#> 11 999 2020-09-07 230 MINIMUM 162.83456 162.834559197379 mm 137.2934
#> 12 0 2020-01-21 0 NA <NA> mm 137.2934
#> 13 2 2020-11-04 288 192.00660 192.006595354685 mm 137.2934
#> 14 -1 2019-10-13 -100 134.70663 134.706625614629 mm 137.2934
#> 15 4 2021-08-28 483 168.40263 168.402625087087 mm 132.9968
#> 16 999 2021-04-27 360 MINIMUM 133.52191 133.521905548814 mm 132.9968
#> 17 -1 2020-01-23 -100 142.36212 142.362118285105 mm 132.9968
#> 18 2 2021-06-29 423 134.27664 134.276636235556 mm 132.9968
#> 19 999 2020-08-19 109 135.26523 135.265230236085 mm 132.9968
#> 20 0 2020-05-02 0 NA <NA> mm 132.9968
#> 21 999 2021-04-27 360 133.52191 133.521905548814 mm 132.9968
#> 22 0 2020-02-26 0 NA <NA> mm 141.9365
#> 23 -1 2019-11-18 -100 139.30736 139.307364831736 mm 141.9365
#> 24 999 2021-03-06 374 198.01823 198.018230416784 mm 141.9365
#> 25 2 2021-05-26 455 132.88408 132.884083286846 mm 141.9365
#> 26 999 2020-03-05 8 133.57914 133.57913565285 mm 141.9365
#> 27 4 2021-07-25 515 MINIMUM 121.63978 121.639776669181 mm 141.9365
#> 28 4 2021-07-25 515 121.63978 121.639776669181 mm 141.9365
#> 29 2 2020-01-25 303 209.04787 209.047870741207 mm 161.6451
#> 30 4 2020-03-25 363 152.92758 152.927578195138 mm 161.6451
#> 31 0 2019-03-28 0 NA <NA> mm 161.6451
#> 32 999 2021-11-14 962 187.63126 187.631264810984 mm 161.6451
#> 33 999 2020-07-05 465 MINIMUM 111.73624 111.736235465107 mm 161.6451
#> 34 999 2020-07-05 465 111.73624 111.736235465107 mm 161.6451
#> 35 -1 2018-12-18 -100 171.03331 171.033308539064 mm 161.6451
#> 36 2 2022-11-05 861 153.31581 153.315812444564 mm 117.4207
#> 37 999 2023-03-28 1004 179.47970 179.479703823713 mm 117.4207
#> 38 999 2022-05-03 675 173.19144 173.191438067149 mm 117.4207
#> 39 0 2020-06-27 0 NA <NA> mm 117.4207
#> 40 2 2022-11-05 861 MINIMUM 153.31581 153.315812444564 mm 117.4207
#> 41 4 2023-01-04 921 155.42461 155.424614142239 mm 117.4207
#> 42 -1 2020-03-19 -100 174.64144 174.641438730238 mm 117.4207
#> 43 4 2021-09-18 727 MINIMUM 120.75645 120.756454557208 mm 107.3777
#> 44 999 2020-12-11 446 122.32514 122.325137102402 mm 107.3777
#> 45 0 2019-09-22 0 NA <NA> mm 107.3777
#> 46 999 2020-09-13 357 124.91752 124.917520384125 mm 107.3777
#> 47 -1 2019-06-14 -100 170.10272 170.102716143127 mm 107.3777
#> 48 2 2021-07-20 667 142.91768 142.91768207549 mm 107.3777
#> 49 4 2021-09-18 727 120.75645 120.756454557208 mm 107.3777
#> 50 -1 2020-05-20 -100 116.29608 116.296079891356 mm 161.1686
#> 51 2 2021-07-21 327 207.32206 207.322064439334 mm 161.1686
#> 52 4 2021-09-19 387 177.35987 177.359868282648 mm 161.1686
#> 53 0 2020-08-28 0 NA <NA> mm 161.1686
#> 54 999 2021-02-25 181 MINIMUM 125.44212 125.442123033571 mm 161.1686
#> 55 999 2021-10-20 418 128.86572 128.865720965572 mm 161.1686
#> 56 999 2021-02-25 181 125.44212 125.442123033571 mm 161.1686
#> 57 0 2020-10-26 0 NA <NA> mm 163.2708
#> 58 -1 2020-07-18 -100 151.82471 151.824708256163 mm 163.2708
#> 59 999 2021-04-09 165 125.77553 125.775527169834 mm 163.2708
#> 60 999 2023-03-25 880 195.61622 195.616215766854 mm 163.2708
#> 61 4 2023-02-09 836 MINIMUM 82.85676 82.8567640271941 mm 163.2708
#> 62 2 2022-12-11 776 102.75526 102.75525794363 mm 163.2708
#> 63 4 2023-02-09 836 82.85676 82.8567640271941 mm 163.2708
#> 64 999 2020-06-13 240 MINIMUM 137.60168 137.60167522998 mm 181.6170
#> 65 999 2021-12-03 778 152.16982 152.169817521355 mm 181.6170
#> 66 4 2022-04-04 900 178.59575 178.595745543059 mm 181.6170
#> 67 999 2020-06-13 240 137.60168 137.60167522998 mm 181.6170
#> 68 -1 2019-07-09 -100 148.93469 148.934693049719 mm 181.6170
#> 69 2 2022-02-03 840 148.18341 148.183410802958 mm 181.6170
#> 70 0 2019-10-17 0 NA <NA> mm 181.6170
#> ABLFL CHG PCHG ONTRTFL ANL01FL ANL02FL ANL03FL
#> 1 57.6283037 50.8668175 Y Y
#> 2 16.0259607 14.1456466 Y Y
#> 3 NA NA
#> 4 Y NA NA Y Y
#> 5 41.9224946 37.0037594 Y Y
#> 6 16.0259607 14.1456466 Y Y Y
#> 7 72.8324422 64.2870658 Y
#> 8 25.5411754 18.6033549 Y Y
#> 9 66.5892586 48.5014331 Y Y
#> 10 39.9166292 29.0739642 Y Y
#> 11 25.5411754 18.6033549 Y Y
#> 12 Y NA NA Y Y
#> 13 54.7132116 39.8513097 Y Y
#> 14 NA NA
#> 15 35.4058146 26.6215517 Y Y Y
#> 16 0.5250951 0.3948178 Y Y
#> 17 NA NA
#> 18 1.2798258 0.9622981 Y Y
#> 19 2.2684198 1.7056197 Y Y
#> 20 Y NA NA Y Y
#> 21 0.5250951 0.3948178 Y
#> 22 Y NA NA Y Y
#> 23 NA NA
#> 24 56.0817767 39.5118909 Y Y
#> 25 -9.0523704 -6.3777629 Y Y
#> 26 -8.3573181 -5.8880702 Y
#> 27 -20.2966771 -14.2998339 Y Y
#> 28 -20.2966771 -14.2998339 Y Y Y
#> 29 47.4028071 29.3252426 Y Y
#> 30 -8.7174854 -5.3929797 Y Y
#> 31 Y NA NA Y Y
#> 32 25.9862012 16.0760871 Y Y Y
#> 33 -49.9088282 -30.8755659 Y Y
#> 34 -49.9088282 -30.8755659 Y
#> 35 NA NA
#> 36 35.8951600 30.5697160 Y Y
#> 37 62.0590514 52.8519048 Y Y Y
#> 38 55.7707856 47.4965728 Y
#> 39 Y NA NA Y Y
#> 40 35.8951600 30.5697160 Y Y
#> 41 38.0039617 32.3656537 Y Y
#> 42 NA NA
#> 43 13.3787815 12.4595562 Y Y
#> 44 14.9474641 13.9204582 Y Y
#> 45 Y NA NA Y Y
#> 46 17.5398474 16.3347248 Y
#> 47 NA NA
#> 48 35.5400090 33.0981367 Y Y
#> 49 13.3787815 12.4595562 Y Y Y
#> 50 NA NA
#> 51 46.1534587 28.6367549 Y Y
#> 52 16.1912625 10.0461640 Y Y
#> 53 Y NA NA Y Y
#> 54 -35.7264827 -22.1671476 Y Y
#> 55 -32.3028848 -20.0429138 Y Y Y
#> 56 -35.7264827 -22.1671476 Y
#> 57 Y NA NA Y Y
#> 58 NA NA
#> 59 -37.4952615 -22.9650765 Y
#> 60 32.3454271 19.8109089 Y Y Y
#> 61 -80.4140246 -49.2519362 Y Y
#> 62 -60.5155307 -37.0645179 Y Y
#> 63 -80.4140246 -49.2519362 Y Y
#> 64 -44.0153038 -24.2352362 Y Y
#> 65 -29.4471615 -16.2138814 Y Y
#> 66 -3.0212335 -1.6635193 Y Y Y
#> 67 -44.0153038 -24.2352362 Y
#> 68 NA NA
#> 69 -33.4335682 -18.4088340 Y Y
#> 70 Y NA NA Y Y