Protocol Deviations Analysis Dataset (ADDV)
raddv.Rd
Function for generating random Protocol Deviations Analysis Dataset for a given Subject-Level Analysis Dataset.
Arguments
- adsl
(
data.frame
)
Subject-Level Analysis Dataset (ADSL).- max_n_dv
(
integer
)
Maximum number of deviations per patient. Defaults to 3.- p_dv
(
proportion
)
Probability of a patient having protocol deviations.- lookup
(
data.frame
)
Additional parameters.- seed
(
numeric
)
Seed to use for reproducible random number generation.- na_percentage
(
proportion
)
Default percentage of values to be replaced byNA
.- na_vars
(
list
)
A named list where the name of each element is a column name ofds
. Each element of this list should be a numeric vector with two elements:seed
(numeric
)
The seed to be used for this element - can beNA
.percentage
(proportion
)
Percentage of elements to be replaced withNA
. IfNA
,na_percentage
is used as a default.
- cached
boolean whether the cached ADDV data
caddv
should be returned or new data should be generated. If set toTRUE
then the other arguments toraddv
will be ignored.
Details
One record per each record in the corresponding SDTM domain.
Keys: STUDYID
, USUBJID
, ASTDT
, DVTERM
, DVSEQ
Examples
library(random.cdisc.data)
adsl <- radsl(N = 10, seed = 1, study_duration = 2)
addv <- raddv(adsl, seed = 2)
addv
#> # A tibble: 9 × 66
#> STUDYID USUBJID SUBJID SITEID AGE AGEU SEX RACE ETHNIC COUNTRY DTHFL
#> <chr> <chr> <chr> <chr> <int> <fct> <fct> <fct> <fct> <fct> <fct>
#> 1 AB12345 AB12345-BR… id-9 BRA-1 35 YEARS F BLAC… UNKNO… BRA N
#> 2 AB12345 AB12345-BR… id-9 BRA-1 35 YEARS F BLAC… UNKNO… BRA N
#> 3 AB12345 AB12345-BR… id-9 BRA-1 35 YEARS F BLAC… UNKNO… BRA N
#> 4 AB12345 AB12345-CH… id-5 CHN-3 36 YEARS F ASIAN NOT H… CHN N
#> 5 AB12345 AB12345-CH… id-5 CHN-3 36 YEARS F ASIAN NOT H… CHN N
#> 6 AB12345 AB12345-CH… id-5 CHN-3 36 YEARS F ASIAN NOT H… CHN N
#> 7 AB12345 AB12345-US… id-3 USA-13 35 YEARS F AMER… NOT H… USA N
#> 8 AB12345 AB12345-US… id-3 USA-13 35 YEARS F AMER… NOT H… USA N
#> 9 AB12345 AB12345-US… id-3 USA-13 35 YEARS F AMER… NOT H… USA N
#> # ℹ 55 more variables: INVID <chr>, INVNAM <chr>, ARM <fct>, ARMCD <fct>,
#> # ACTARM <fct>, ACTARMCD <fct>, TRT01P <fct>, TRT01A <fct>, TRT02P <fct>,
#> # TRT02A <fct>, REGION1 <fct>, STRATA1 <fct>, STRATA2 <fct>, BMRKR1 <dbl>,
#> # BMRKR2 <fct>, ITTFL <fct>, SAFFL <fct>, BMEASIFL <fct>, BEP01FL <fct>,
#> # AEWITHFL <fct>, RANDDT <date>, TRTSDTM <dttm>, TRTEDTM <dttm>,
#> # TRT01SDTM <dttm>, TRT01EDTM <dttm>, TRT02SDTM <dttm>, TRT02EDTM <dttm>,
#> # AP01SDTM <dttm>, AP01EDTM <dttm>, AP02SDTM <dttm>, AP02EDTM <dttm>, …