radtr.RdFunction for generating random dataset from Tumor Response Analysis Dataset for a given Subject-Level Analysis Dataset.
Subject-Level Analysis Dataset (ADSL).
As character string. list of parameter values.
As character string. list of parameter code values.
Seed for random number generation.
boolean whether the cached ADTR data cadtr should be returned or new data
should be generated. If set to TRUE then the other arguments to radtr will be ignored.
parameters from radrs
data.frame
One record per subject per parameter per analysis visit per analysis date.
Keys: STUDYID, USUBJID, PARAMCD, BASETYPE, AVISITN, DTYPE
library(random.cdisc.data)
ADSL <- radsl(N = 10, seed = 1, study_duration = 2)
radtr(ADSL, seed = 2)
#> STUDYID USUBJID SUBJID SITEID AGE AGEU SEX
#> 1 AB12345 AB12345-BRA-1-id-9 id-9 BRA-1 35 YEARS F
#> 2 AB12345 AB12345-BRA-1-id-9 id-9 BRA-1 35 YEARS F
#> 3 AB12345 AB12345-BRA-1-id-9 id-9 BRA-1 35 YEARS F
#> 4 AB12345 AB12345-BRA-1-id-9 id-9 BRA-1 35 YEARS F
#> 5 AB12345 AB12345-BRA-1-id-9 id-9 BRA-1 35 YEARS F
#> 6 AB12345 AB12345-BRA-1-id-9 id-9 BRA-1 35 YEARS F
#> 7 AB12345 AB12345-BRA-1-id-9 id-9 BRA-1 35 YEARS F
#> 8 AB12345 AB12345-BRA-9-id-8 id-8 BRA-9 31 YEARS F
#> 9 AB12345 AB12345-BRA-9-id-8 id-8 BRA-9 31 YEARS F
#> 10 AB12345 AB12345-BRA-9-id-8 id-8 BRA-9 31 YEARS F
#> 11 AB12345 AB12345-BRA-9-id-8 id-8 BRA-9 31 YEARS F
#> 12 AB12345 AB12345-BRA-9-id-8 id-8 BRA-9 31 YEARS F
#> 13 AB12345 AB12345-BRA-9-id-8 id-8 BRA-9 31 YEARS F
#> 14 AB12345 AB12345-BRA-9-id-8 id-8 BRA-9 31 YEARS F
#> 15 AB12345 AB12345-CHN-11-id-1 id-1 CHN-11 35 YEARS F
#> 16 AB12345 AB12345-CHN-11-id-1 id-1 CHN-11 35 YEARS F
#> 17 AB12345 AB12345-CHN-11-id-1 id-1 CHN-11 35 YEARS F
#> 18 AB12345 AB12345-CHN-11-id-1 id-1 CHN-11 35 YEARS F
#> 19 AB12345 AB12345-CHN-11-id-1 id-1 CHN-11 35 YEARS F
#> 20 AB12345 AB12345-CHN-11-id-1 id-1 CHN-11 35 YEARS F
#> 21 AB12345 AB12345-CHN-11-id-1 id-1 CHN-11 35 YEARS F
#> 22 AB12345 AB12345-CHN-11-id-2 id-2 CHN-11 35 YEARS M
#> 23 AB12345 AB12345-CHN-11-id-2 id-2 CHN-11 35 YEARS M
#> 24 AB12345 AB12345-CHN-11-id-2 id-2 CHN-11 35 YEARS M
#> 25 AB12345 AB12345-CHN-11-id-2 id-2 CHN-11 35 YEARS M
#> 26 AB12345 AB12345-CHN-11-id-2 id-2 CHN-11 35 YEARS M
#> 27 AB12345 AB12345-CHN-11-id-2 id-2 CHN-11 35 YEARS M
#> 28 AB12345 AB12345-CHN-11-id-2 id-2 CHN-11 35 YEARS M
#> 29 AB12345 AB12345-CHN-3-id-10 id-10 CHN-3 35 YEARS M
#> 30 AB12345 AB12345-CHN-3-id-10 id-10 CHN-3 35 YEARS M
#> 31 AB12345 AB12345-CHN-3-id-10 id-10 CHN-3 35 YEARS M
#> 32 AB12345 AB12345-CHN-3-id-10 id-10 CHN-3 35 YEARS M
#> 33 AB12345 AB12345-CHN-3-id-10 id-10 CHN-3 35 YEARS M
#> 34 AB12345 AB12345-CHN-3-id-10 id-10 CHN-3 35 YEARS M
#> 35 AB12345 AB12345-CHN-3-id-10 id-10 CHN-3 35 YEARS M
#> 36 AB12345 AB12345-CHN-3-id-5 id-5 CHN-3 36 YEARS F
#> 37 AB12345 AB12345-CHN-3-id-5 id-5 CHN-3 36 YEARS F
#> 38 AB12345 AB12345-CHN-3-id-5 id-5 CHN-3 36 YEARS F
#> 39 AB12345 AB12345-CHN-3-id-5 id-5 CHN-3 36 YEARS F
#> 40 AB12345 AB12345-CHN-3-id-5 id-5 CHN-3 36 YEARS F
#> 41 AB12345 AB12345-CHN-3-id-5 id-5 CHN-3 36 YEARS F
#> 42 AB12345 AB12345-CHN-3-id-5 id-5 CHN-3 36 YEARS F
#> 43 AB12345 AB12345-JPN-4-id-7 id-7 JPN-4 30 YEARS F
#> 44 AB12345 AB12345-JPN-4-id-7 id-7 JPN-4 30 YEARS F
#> 45 AB12345 AB12345-JPN-4-id-7 id-7 JPN-4 30 YEARS F
#> 46 AB12345 AB12345-JPN-4-id-7 id-7 JPN-4 30 YEARS F
#> 47 AB12345 AB12345-JPN-4-id-7 id-7 JPN-4 30 YEARS F
#> 48 AB12345 AB12345-JPN-4-id-7 id-7 JPN-4 30 YEARS F
#> 49 AB12345 AB12345-JPN-4-id-7 id-7 JPN-4 30 YEARS F
#> 50 AB12345 AB12345-RUS-1-id-4 id-4 RUS-1 36 YEARS M
#> 51 AB12345 AB12345-RUS-1-id-4 id-4 RUS-1 36 YEARS M
#> 52 AB12345 AB12345-RUS-1-id-4 id-4 RUS-1 36 YEARS M
#> 53 AB12345 AB12345-RUS-1-id-4 id-4 RUS-1 36 YEARS M
#> 54 AB12345 AB12345-RUS-1-id-4 id-4 RUS-1 36 YEARS M
#> 55 AB12345 AB12345-RUS-1-id-4 id-4 RUS-1 36 YEARS M
#> 56 AB12345 AB12345-RUS-1-id-4 id-4 RUS-1 36 YEARS M
#> 57 AB12345 AB12345-RUS-1-id-6 id-6 RUS-1 36 YEARS F
#> 58 AB12345 AB12345-RUS-1-id-6 id-6 RUS-1 36 YEARS F
#> 59 AB12345 AB12345-RUS-1-id-6 id-6 RUS-1 36 YEARS F
#> 60 AB12345 AB12345-RUS-1-id-6 id-6 RUS-1 36 YEARS F
#> 61 AB12345 AB12345-RUS-1-id-6 id-6 RUS-1 36 YEARS F
#> 62 AB12345 AB12345-RUS-1-id-6 id-6 RUS-1 36 YEARS F
#> 63 AB12345 AB12345-RUS-1-id-6 id-6 RUS-1 36 YEARS F
#> 64 AB12345 AB12345-USA-13-id-3 id-3 USA-13 35 YEARS F
#> 65 AB12345 AB12345-USA-13-id-3 id-3 USA-13 35 YEARS F
#> 66 AB12345 AB12345-USA-13-id-3 id-3 USA-13 35 YEARS F
#> 67 AB12345 AB12345-USA-13-id-3 id-3 USA-13 35 YEARS F
#> 68 AB12345 AB12345-USA-13-id-3 id-3 USA-13 35 YEARS F
#> 69 AB12345 AB12345-USA-13-id-3 id-3 USA-13 35 YEARS F
#> 70 AB12345 AB12345-USA-13-id-3 id-3 USA-13 35 YEARS F
#> RACE ETHNIC COUNTRY DTHFL
#> 1 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO BRA N
#> 2 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO BRA N
#> 3 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO BRA N
#> 4 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO BRA N
#> 5 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO BRA N
#> 6 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO BRA N
#> 7 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO BRA N
#> 8 ASIAN NOT HISPANIC OR LATINO BRA N
#> 9 ASIAN NOT HISPANIC OR LATINO BRA N
#> 10 ASIAN NOT HISPANIC OR LATINO BRA N
#> 11 ASIAN NOT HISPANIC OR LATINO BRA N
#> 12 ASIAN NOT HISPANIC OR LATINO BRA N
#> 13 ASIAN NOT HISPANIC OR LATINO BRA N
#> 14 ASIAN NOT HISPANIC OR LATINO BRA N
#> 15 WHITE UNKNOWN CHN N
#> 16 WHITE UNKNOWN CHN N
#> 17 WHITE UNKNOWN CHN N
#> 18 WHITE UNKNOWN CHN N
#> 19 WHITE UNKNOWN CHN N
#> 20 WHITE UNKNOWN CHN N
#> 21 WHITE UNKNOWN CHN N
#> 22 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO CHN Y
#> 23 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO CHN Y
#> 24 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO CHN Y
#> 25 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO CHN Y
#> 26 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO CHN Y
#> 27 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO CHN Y
#> 28 BLACK OR AFRICAN AMERICAN NOT HISPANIC OR LATINO CHN Y
#> 29 ASIAN NOT HISPANIC OR LATINO CHN N
#> 30 ASIAN NOT HISPANIC OR LATINO CHN N
#> 31 ASIAN NOT HISPANIC OR LATINO CHN N
#> 32 ASIAN NOT HISPANIC OR LATINO CHN N
#> 33 ASIAN NOT HISPANIC OR LATINO CHN N
#> 34 ASIAN NOT HISPANIC OR LATINO CHN N
#> 35 ASIAN NOT HISPANIC OR LATINO CHN N
#> 36 ASIAN NOT HISPANIC OR LATINO CHN N
#> 37 ASIAN NOT HISPANIC OR LATINO CHN N
#> 38 ASIAN NOT HISPANIC OR LATINO CHN N
#> 39 ASIAN NOT HISPANIC OR LATINO CHN N
#> 40 ASIAN NOT HISPANIC OR LATINO CHN N
#> 41 ASIAN NOT HISPANIC OR LATINO CHN N
#> 42 ASIAN NOT HISPANIC OR LATINO CHN N
#> 43 ASIAN NOT HISPANIC OR LATINO JPN N
#> 44 ASIAN NOT HISPANIC OR LATINO JPN N
#> 45 ASIAN NOT HISPANIC OR LATINO JPN N
#> 46 ASIAN NOT HISPANIC OR LATINO JPN N
#> 47 ASIAN NOT HISPANIC OR LATINO JPN N
#> 48 ASIAN NOT HISPANIC OR LATINO JPN N
#> 49 ASIAN NOT HISPANIC OR LATINO JPN N
#> 50 BLACK OR AFRICAN AMERICAN HISPANIC OR LATINO RUS N
#> 51 BLACK OR AFRICAN AMERICAN HISPANIC OR LATINO RUS N
#> 52 BLACK OR AFRICAN AMERICAN HISPANIC OR LATINO RUS N
#> 53 BLACK OR AFRICAN AMERICAN HISPANIC OR LATINO RUS N
#> 54 BLACK OR AFRICAN AMERICAN HISPANIC OR LATINO RUS N
#> 55 BLACK OR AFRICAN AMERICAN HISPANIC OR LATINO RUS N
#> 56 BLACK OR AFRICAN AMERICAN HISPANIC OR LATINO RUS N
#> 57 ASIAN NOT HISPANIC OR LATINO RUS Y
#> 58 ASIAN NOT HISPANIC OR LATINO RUS Y
#> 59 ASIAN NOT HISPANIC OR LATINO RUS Y
#> 60 ASIAN NOT HISPANIC OR LATINO RUS Y
#> 61 ASIAN NOT HISPANIC OR LATINO RUS Y
#> 62 ASIAN NOT HISPANIC OR LATINO RUS Y
#> 63 ASIAN NOT HISPANIC OR LATINO RUS Y
#> 64 AMERICAN INDIAN OR ALASKA NATIVE NOT HISPANIC OR LATINO USA N
#> 65 AMERICAN INDIAN OR ALASKA NATIVE NOT HISPANIC OR LATINO USA N
#> 66 AMERICAN INDIAN OR ALASKA NATIVE NOT HISPANIC OR LATINO USA N
#> 67 AMERICAN INDIAN OR ALASKA NATIVE NOT HISPANIC OR LATINO USA N
#> 68 AMERICAN INDIAN OR ALASKA NATIVE NOT HISPANIC OR LATINO USA N
#> 69 AMERICAN INDIAN OR ALASKA NATIVE NOT HISPANIC OR LATINO USA N
#> 70 AMERICAN INDIAN OR ALASKA NATIVE NOT HISPANIC OR LATINO USA N
#> INVID INVNAM ARM ARMCD ACTARM ACTARMCD
#> 1 INV ID BRA-1 Dr. BRA-1 Doe C: Combination ARM C C: Combination ARM C
#> 2 INV ID BRA-1 Dr. BRA-1 Doe C: Combination ARM C C: Combination ARM C
#> 3 INV ID BRA-1 Dr. BRA-1 Doe C: Combination ARM C C: Combination ARM C
#> 4 INV ID BRA-1 Dr. BRA-1 Doe C: Combination ARM C C: Combination ARM C
#> 5 INV ID BRA-1 Dr. BRA-1 Doe C: Combination ARM C C: Combination ARM C
#> 6 INV ID BRA-1 Dr. BRA-1 Doe C: Combination ARM C C: Combination ARM C
#> 7 INV ID BRA-1 Dr. BRA-1 Doe C: Combination ARM C C: Combination ARM C
#> 8 INV ID BRA-9 Dr. BRA-9 Doe A: Drug X ARM A A: Drug X ARM A
#> 9 INV ID BRA-9 Dr. BRA-9 Doe A: Drug X ARM A A: Drug X ARM A
#> 10 INV ID BRA-9 Dr. BRA-9 Doe A: Drug X ARM A A: Drug X ARM A
#> 11 INV ID BRA-9 Dr. BRA-9 Doe A: Drug X ARM A A: Drug X ARM A
#> 12 INV ID BRA-9 Dr. BRA-9 Doe A: Drug X ARM A A: Drug X ARM A
#> 13 INV ID BRA-9 Dr. BRA-9 Doe A: Drug X ARM A A: Drug X ARM A
#> 14 INV ID BRA-9 Dr. BRA-9 Doe A: Drug X ARM A A: Drug X ARM A
#> 15 INV ID CHN-11 Dr. CHN-11 Doe C: Combination ARM C C: Combination ARM C
#> 16 INV ID CHN-11 Dr. CHN-11 Doe C: Combination ARM C C: Combination ARM C
#> 17 INV ID CHN-11 Dr. CHN-11 Doe C: Combination ARM C C: Combination ARM C
#> 18 INV ID CHN-11 Dr. CHN-11 Doe C: Combination ARM C C: Combination ARM C
#> 19 INV ID CHN-11 Dr. CHN-11 Doe C: Combination ARM C C: Combination ARM C
#> 20 INV ID CHN-11 Dr. CHN-11 Doe C: Combination ARM C C: Combination ARM C
#> 21 INV ID CHN-11 Dr. CHN-11 Doe C: Combination ARM C C: Combination ARM C
#> 22 INV ID CHN-11 Dr. CHN-11 Doe A: Drug X ARM A A: Drug X ARM A
#> 23 INV ID CHN-11 Dr. CHN-11 Doe A: Drug X ARM A A: Drug X ARM A
#> 24 INV ID CHN-11 Dr. CHN-11 Doe A: Drug X ARM A A: Drug X ARM A
#> 25 INV ID CHN-11 Dr. CHN-11 Doe A: Drug X ARM A A: Drug X ARM A
#> 26 INV ID CHN-11 Dr. CHN-11 Doe A: Drug X ARM A A: Drug X ARM A
#> 27 INV ID CHN-11 Dr. CHN-11 Doe A: Drug X ARM A A: Drug X ARM A
#> 28 INV ID CHN-11 Dr. CHN-11 Doe A: Drug X ARM A A: Drug X ARM A
#> 29 INV ID CHN-3 Dr. CHN-3 Doe B: Placebo ARM B B: Placebo ARM B
#> 30 INV ID CHN-3 Dr. CHN-3 Doe B: Placebo ARM B B: Placebo ARM B
#> 31 INV ID CHN-3 Dr. CHN-3 Doe B: Placebo ARM B B: Placebo ARM B
#> 32 INV ID CHN-3 Dr. CHN-3 Doe B: Placebo ARM B B: Placebo ARM B
#> 33 INV ID CHN-3 Dr. CHN-3 Doe B: Placebo ARM B B: Placebo ARM B
#> 34 INV ID CHN-3 Dr. CHN-3 Doe B: Placebo ARM B B: Placebo ARM B
#> 35 INV ID CHN-3 Dr. CHN-3 Doe B: Placebo ARM B B: Placebo ARM B
#> 36 INV ID CHN-3 Dr. CHN-3 Doe A: Drug X ARM A A: Drug X ARM A
#> 37 INV ID CHN-3 Dr. CHN-3 Doe A: Drug X ARM A A: Drug X ARM A
#> 38 INV ID CHN-3 Dr. CHN-3 Doe A: Drug X ARM A A: Drug X ARM A
#> 39 INV ID CHN-3 Dr. CHN-3 Doe A: Drug X ARM A A: Drug X ARM A
#> 40 INV ID CHN-3 Dr. CHN-3 Doe A: Drug X ARM A A: Drug X ARM A
#> 41 INV ID CHN-3 Dr. CHN-3 Doe A: Drug X ARM A A: Drug X ARM A
#> 42 INV ID CHN-3 Dr. CHN-3 Doe A: Drug X ARM A A: Drug X ARM A
#> 43 INV ID JPN-4 Dr. JPN-4 Doe A: Drug X ARM A A: Drug X ARM A
#> 44 INV ID JPN-4 Dr. JPN-4 Doe A: Drug X ARM A A: Drug X ARM A
#> 45 INV ID JPN-4 Dr. JPN-4 Doe A: Drug X ARM A A: Drug X ARM A
#> 46 INV ID JPN-4 Dr. JPN-4 Doe A: Drug X ARM A A: Drug X ARM A
#> 47 INV ID JPN-4 Dr. JPN-4 Doe A: Drug X ARM A A: Drug X ARM A
#> 48 INV ID JPN-4 Dr. JPN-4 Doe A: Drug X ARM A A: Drug X ARM A
#> 49 INV ID JPN-4 Dr. JPN-4 Doe A: Drug X ARM A A: Drug X ARM A
#> 50 INV ID RUS-1 Dr. RUS-1 Doe B: Placebo ARM B B: Placebo ARM B
#> 51 INV ID RUS-1 Dr. RUS-1 Doe B: Placebo ARM B B: Placebo ARM B
#> 52 INV ID RUS-1 Dr. RUS-1 Doe B: Placebo ARM B B: Placebo ARM B
#> 53 INV ID RUS-1 Dr. RUS-1 Doe B: Placebo ARM B B: Placebo ARM B
#> 54 INV ID RUS-1 Dr. RUS-1 Doe B: Placebo ARM B B: Placebo ARM B
#> 55 INV ID RUS-1 Dr. RUS-1 Doe B: Placebo ARM B B: Placebo ARM B
#> 56 INV ID RUS-1 Dr. RUS-1 Doe B: Placebo ARM B B: Placebo ARM B
#> 57 INV ID RUS-1 Dr. RUS-1 Doe A: Drug X ARM A A: Drug X ARM A
#> 58 INV ID RUS-1 Dr. RUS-1 Doe A: Drug X ARM A A: Drug X ARM A
#> 59 INV ID RUS-1 Dr. RUS-1 Doe A: Drug X ARM A A: Drug X ARM A
#> 60 INV ID RUS-1 Dr. RUS-1 Doe A: Drug X ARM A A: Drug X ARM A
#> 61 INV ID RUS-1 Dr. RUS-1 Doe A: Drug X ARM A A: Drug X ARM A
#> 62 INV ID RUS-1 Dr. RUS-1 Doe A: Drug X ARM A A: Drug X ARM A
#> 63 INV ID RUS-1 Dr. RUS-1 Doe A: Drug X ARM A A: Drug X ARM A
#> 64 INV ID USA-13 Dr. USA-13 Doe A: Drug X ARM A A: Drug X ARM A
#> 65 INV ID USA-13 Dr. USA-13 Doe A: Drug X ARM A A: Drug X ARM A
#> 66 INV ID USA-13 Dr. USA-13 Doe A: Drug X ARM A A: Drug X ARM A
#> 67 INV ID USA-13 Dr. USA-13 Doe A: Drug X ARM A A: Drug X ARM A
#> 68 INV ID USA-13 Dr. USA-13 Doe A: Drug X ARM A A: Drug X ARM A
#> 69 INV ID USA-13 Dr. USA-13 Doe A: Drug X ARM A A: Drug X ARM A
#> 70 INV ID USA-13 Dr. USA-13 Doe A: Drug X ARM A A: Drug X ARM A
#> TRT01P TRT01A REGION1 STRATA1 STRATA2 BMRKR1 BMRKR2
#> 1 C: Combination C: Combination South America A S1 6.922043 HIGH
#> 2 C: Combination C: Combination South America A S1 6.922043 HIGH
#> 3 C: Combination C: Combination South America A S1 6.922043 HIGH
#> 4 C: Combination C: Combination South America A S1 6.922043 HIGH
#> 5 C: Combination C: Combination South America A S1 6.922043 HIGH
#> 6 C: Combination C: Combination South America A S1 6.922043 HIGH
#> 7 C: Combination C: Combination South America A S1 6.922043 HIGH
#> 8 A: Drug X A: Drug X South America B S2 11.277028 MEDIUM
#> 9 A: Drug X A: Drug X South America B S2 11.277028 MEDIUM
#> 10 A: Drug X A: Drug X South America B S2 11.277028 MEDIUM
#> 11 A: Drug X A: Drug X South America B S2 11.277028 MEDIUM
#> 12 A: Drug X A: Drug X South America B S2 11.277028 MEDIUM
#> 13 A: Drug X A: Drug X South America B S2 11.277028 MEDIUM
#> 14 A: Drug X A: Drug X South America B S2 11.277028 MEDIUM
#> 15 C: Combination C: Combination Asia B S1 8.926907 LOW
#> 16 C: Combination C: Combination Asia B S1 8.926907 LOW
#> 17 C: Combination C: Combination Asia B S1 8.926907 LOW
#> 18 C: Combination C: Combination Asia B S1 8.926907 LOW
#> 19 C: Combination C: Combination Asia B S1 8.926907 LOW
#> 20 C: Combination C: Combination Asia B S1 8.926907 LOW
#> 21 C: Combination C: Combination Asia B S1 8.926907 LOW
#> 22 A: Drug X A: Drug X Asia C S2 4.084350 HIGH
#> 23 A: Drug X A: Drug X Asia C S2 4.084350 HIGH
#> 24 A: Drug X A: Drug X Asia C S2 4.084350 HIGH
#> 25 A: Drug X A: Drug X Asia C S2 4.084350 HIGH
#> 26 A: Drug X A: Drug X Asia C S2 4.084350 HIGH
#> 27 A: Drug X A: Drug X Asia C S2 4.084350 HIGH
#> 28 A: Drug X A: Drug X Asia C S2 4.084350 HIGH
#> 29 B: Placebo B: Placebo Asia A S1 1.777905 LOW
#> 30 B: Placebo B: Placebo Asia A S1 1.777905 LOW
#> 31 B: Placebo B: Placebo Asia A S1 1.777905 LOW
#> 32 B: Placebo B: Placebo Asia A S1 1.777905 LOW
#> 33 B: Placebo B: Placebo Asia A S1 1.777905 LOW
#> 34 B: Placebo B: Placebo Asia A S1 1.777905 LOW
#> 35 B: Placebo B: Placebo Asia A S1 1.777905 LOW
#> 36 A: Drug X A: Drug X Asia A S2 2.619796 LOW
#> 37 A: Drug X A: Drug X Asia A S2 2.619796 LOW
#> 38 A: Drug X A: Drug X Asia A S2 2.619796 LOW
#> 39 A: Drug X A: Drug X Asia A S2 2.619796 LOW
#> 40 A: Drug X A: Drug X Asia A S2 2.619796 LOW
#> 41 A: Drug X A: Drug X Asia A S2 2.619796 LOW
#> 42 A: Drug X A: Drug X Asia A S2 2.619796 LOW
#> 43 A: Drug X A: Drug X Asia B S1 7.459420 MEDIUM
#> 44 A: Drug X A: Drug X Asia B S1 7.459420 MEDIUM
#> 45 A: Drug X A: Drug X Asia B S1 7.459420 MEDIUM
#> 46 A: Drug X A: Drug X Asia B S1 7.459420 MEDIUM
#> 47 A: Drug X A: Drug X Asia B S1 7.459420 MEDIUM
#> 48 A: Drug X A: Drug X Asia B S1 7.459420 MEDIUM
#> 49 A: Drug X A: Drug X Asia B S1 7.459420 MEDIUM
#> 50 B: Placebo B: Placebo Eurasia A S1 9.952892 MEDIUM
#> 51 B: Placebo B: Placebo Eurasia A S1 9.952892 MEDIUM
#> 52 B: Placebo B: Placebo Eurasia A S1 9.952892 MEDIUM
#> 53 B: Placebo B: Placebo Eurasia A S1 9.952892 MEDIUM
#> 54 B: Placebo B: Placebo Eurasia A S1 9.952892 MEDIUM
#> 55 B: Placebo B: Placebo Eurasia A S1 9.952892 MEDIUM
#> 56 B: Placebo B: Placebo Eurasia A S1 9.952892 MEDIUM
#> 57 A: Drug X A: Drug X Eurasia B S1 9.342782 MEDIUM
#> 58 A: Drug X A: Drug X Eurasia B S1 9.342782 MEDIUM
#> 59 A: Drug X A: Drug X Eurasia B S1 9.342782 MEDIUM
#> 60 A: Drug X A: Drug X Eurasia B S1 9.342782 MEDIUM
#> 61 A: Drug X A: Drug X Eurasia B S1 9.342782 MEDIUM
#> 62 A: Drug X A: Drug X Eurasia B S1 9.342782 MEDIUM
#> 63 A: Drug X A: Drug X Eurasia B S1 9.342782 MEDIUM
#> 64 A: Drug X A: Drug X North America C S1 7.254058 LOW
#> 65 A: Drug X A: Drug X North America C S1 7.254058 LOW
#> 66 A: Drug X A: Drug X North America C S1 7.254058 LOW
#> 67 A: Drug X A: Drug X North America C S1 7.254058 LOW
#> 68 A: Drug X A: Drug X North America C S1 7.254058 LOW
#> 69 A: Drug X A: Drug X North America C S1 7.254058 LOW
#> 70 A: Drug X A: Drug X North America C S1 7.254058 LOW
#> ITTFL SAFFL BMEASIFL BEP01FL RANDDT TRTSDTM
#> 1 Y Y Y N 2021-01-17 2021-01-17 22:43:53
#> 2 Y Y Y N 2021-01-17 2021-01-17 22:43:53
#> 3 Y Y Y N 2021-01-17 2021-01-17 22:43:53
#> 4 Y Y Y N 2021-01-17 2021-01-17 22:43:53
#> 5 Y Y Y N 2021-01-17 2021-01-17 22:43:53
#> 6 Y Y Y N 2021-01-17 2021-01-17 22:43:53
#> 7 Y Y Y N 2021-01-17 2021-01-17 22:43:53
#> 8 Y Y Y Y 2020-01-18 2020-01-21 10:19:08
#> 9 Y Y Y Y 2020-01-18 2020-01-21 10:19:08
#> 10 Y Y Y Y 2020-01-18 2020-01-21 10:19:08
#> 11 Y Y Y Y 2020-01-18 2020-01-21 10:19:08
#> 12 Y Y Y Y 2020-01-18 2020-01-21 10:19:08
#> 13 Y Y Y Y 2020-01-18 2020-01-21 10:19:08
#> 14 Y Y Y Y 2020-01-18 2020-01-21 10:19:08
#> 15 Y Y N N 2020-04-29 2020-05-02 02:28:45
#> 16 Y Y N N 2020-04-29 2020-05-02 02:28:45
#> 17 Y Y N N 2020-04-29 2020-05-02 02:28:45
#> 18 Y Y N N 2020-04-29 2020-05-02 02:28:45
#> 19 Y Y N N 2020-04-29 2020-05-02 02:28:45
#> 20 Y Y N N 2020-04-29 2020-05-02 02:28:45
#> 21 Y Y N N 2020-04-29 2020-05-02 02:28:45
#> 22 Y Y Y Y 2020-02-23 2020-02-26 18:15:59
#> 23 Y Y Y Y 2020-02-23 2020-02-26 18:15:59
#> 24 Y Y Y Y 2020-02-23 2020-02-26 18:15:59
#> 25 Y Y Y Y 2020-02-23 2020-02-26 18:15:59
#> 26 Y Y Y Y 2020-02-23 2020-02-26 18:15:59
#> 27 Y Y Y Y 2020-02-23 2020-02-26 18:15:59
#> 28 Y Y Y Y 2020-02-23 2020-02-26 18:15:59
#> 29 Y Y N Y 2019-03-24 2019-03-28 12:07:16
#> 30 Y Y N Y 2019-03-24 2019-03-28 12:07:16
#> 31 Y Y N Y 2019-03-24 2019-03-28 12:07:16
#> 32 Y Y N Y 2019-03-24 2019-03-28 12:07:16
#> 33 Y Y N Y 2019-03-24 2019-03-28 12:07:16
#> 34 Y Y N Y 2019-03-24 2019-03-28 12:07:16
#> 35 Y Y N Y 2019-03-24 2019-03-28 12:07:16
#> 36 Y Y Y N 2020-06-24 2020-06-27 04:48:00
#> 37 Y Y Y N 2020-06-24 2020-06-27 04:48:00
#> 38 Y Y Y N 2020-06-24 2020-06-27 04:48:00
#> 39 Y Y Y N 2020-06-24 2020-06-27 04:48:00
#> 40 Y Y Y N 2020-06-24 2020-06-27 04:48:00
#> 41 Y Y Y N 2020-06-24 2020-06-27 04:48:00
#> 42 Y Y Y N 2020-06-24 2020-06-27 04:48:00
#> 43 Y Y Y N 2019-09-22 2019-09-22 02:25:18
#> 44 Y Y Y N 2019-09-22 2019-09-22 02:25:18
#> 45 Y Y Y N 2019-09-22 2019-09-22 02:25:18
#> 46 Y Y Y N 2019-09-22 2019-09-22 02:25:18
#> 47 Y Y Y N 2019-09-22 2019-09-22 02:25:18
#> 48 Y Y Y N 2019-09-22 2019-09-22 02:25:18
#> 49 Y Y Y N 2019-09-22 2019-09-22 02:25:18
#> 50 Y Y Y N 2020-08-27 2020-08-28 20:42:09
#> 51 Y Y Y N 2020-08-27 2020-08-28 20:42:09
#> 52 Y Y Y N 2020-08-27 2020-08-28 20:42:09
#> 53 Y Y Y N 2020-08-27 2020-08-28 20:42:09
#> 54 Y Y Y N 2020-08-27 2020-08-28 20:42:09
#> 55 Y Y Y N 2020-08-27 2020-08-28 20:42:09
#> 56 Y Y Y N 2020-08-27 2020-08-28 20:42:09
#> 57 Y Y N N 2020-10-24 2020-10-26 22:16:26
#> 58 Y Y N N 2020-10-24 2020-10-26 22:16:26
#> 59 Y Y N N 2020-10-24 2020-10-26 22:16:26
#> 60 Y Y N N 2020-10-24 2020-10-26 22:16:26
#> 61 Y Y N N 2020-10-24 2020-10-26 22:16:26
#> 62 Y Y N N 2020-10-24 2020-10-26 22:16:26
#> 63 Y Y N N 2020-10-24 2020-10-26 22:16:26
#> 64 Y Y Y N 2019-10-16 2019-10-17 17:56:02
#> 65 Y Y Y N 2019-10-16 2019-10-17 17:56:02
#> 66 Y Y Y N 2019-10-16 2019-10-17 17:56:02
#> 67 Y Y Y N 2019-10-16 2019-10-17 17:56:02
#> 68 Y Y Y N 2019-10-16 2019-10-17 17:56:02
#> 69 Y Y Y N 2019-10-16 2019-10-17 17:56:02
#> 70 Y Y Y N 2019-10-16 2019-10-17 17:56:02
#> TRTEDTM EOSSTT EOTSTT EOSDT EOSDY DCSREAS
#> 1 2023-01-18 10:22:17 COMPLETED COMPLETED 2023-01-18 731 <NA>
#> 2 2023-01-18 10:22:17 COMPLETED COMPLETED 2023-01-18 731 <NA>
#> 3 2023-01-18 10:22:17 COMPLETED COMPLETED 2023-01-18 731 <NA>
#> 4 2023-01-18 10:22:17 COMPLETED COMPLETED 2023-01-18 731 <NA>
#> 5 2023-01-18 10:22:17 COMPLETED COMPLETED 2023-01-18 731 <NA>
#> 6 2023-01-18 10:22:17 COMPLETED COMPLETED 2023-01-18 731 <NA>
#> 7 2023-01-18 10:22:17 COMPLETED COMPLETED 2023-01-18 731 <NA>
#> 8 <NA> ONGOING ONGOING <NA> NA <NA>
#> 9 <NA> ONGOING ONGOING <NA> NA <NA>
#> 10 <NA> ONGOING ONGOING <NA> NA <NA>
#> 11 <NA> ONGOING ONGOING <NA> NA <NA>
#> 12 <NA> ONGOING ONGOING <NA> NA <NA>
#> 13 <NA> ONGOING ONGOING <NA> NA <NA>
#> 14 <NA> ONGOING ONGOING <NA> NA <NA>
#> 15 2022-05-02 14:07:09 COMPLETED COMPLETED 2022-05-02 731 <NA>
#> 16 2022-05-02 14:07:09 COMPLETED COMPLETED 2022-05-02 731 <NA>
#> 17 2022-05-02 14:07:09 COMPLETED COMPLETED 2022-05-02 731 <NA>
#> 18 2022-05-02 14:07:09 COMPLETED COMPLETED 2022-05-02 731 <NA>
#> 19 2022-05-02 14:07:09 COMPLETED COMPLETED 2022-05-02 731 <NA>
#> 20 2022-05-02 14:07:09 COMPLETED COMPLETED 2022-05-02 731 <NA>
#> 21 2022-05-02 14:07:09 COMPLETED COMPLETED 2022-05-02 731 <NA>
#> 22 2021-01-22 14:18:49 DISCONTINUED DISCONTINUED 2021-01-22 331 DEATH
#> 23 2021-01-22 14:18:49 DISCONTINUED DISCONTINUED 2021-01-22 331 DEATH
#> 24 2021-01-22 14:18:49 DISCONTINUED DISCONTINUED 2021-01-22 331 DEATH
#> 25 2021-01-22 14:18:49 DISCONTINUED DISCONTINUED 2021-01-22 331 DEATH
#> 26 2021-01-22 14:18:49 DISCONTINUED DISCONTINUED 2021-01-22 331 DEATH
#> 27 2021-01-22 14:18:49 DISCONTINUED DISCONTINUED 2021-01-22 331 DEATH
#> 28 2021-01-22 14:18:49 DISCONTINUED DISCONTINUED 2021-01-22 331 DEATH
#> 29 2021-03-27 23:45:40 COMPLETED COMPLETED 2021-03-27 731 <NA>
#> 30 2021-03-27 23:45:40 COMPLETED COMPLETED 2021-03-27 731 <NA>
#> 31 2021-03-27 23:45:40 COMPLETED COMPLETED 2021-03-27 731 <NA>
#> 32 2021-03-27 23:45:40 COMPLETED COMPLETED 2021-03-27 731 <NA>
#> 33 2021-03-27 23:45:40 COMPLETED COMPLETED 2021-03-27 731 <NA>
#> 34 2021-03-27 23:45:40 COMPLETED COMPLETED 2021-03-27 731 <NA>
#> 35 2021-03-27 23:45:40 COMPLETED COMPLETED 2021-03-27 731 <NA>
#> 36 2020-11-06 15:43:55 DISCONTINUED DISCONTINUED 2020-11-06 133 ADVERSE EVENT
#> 37 2020-11-06 15:43:55 DISCONTINUED DISCONTINUED 2020-11-06 133 ADVERSE EVENT
#> 38 2020-11-06 15:43:55 DISCONTINUED DISCONTINUED 2020-11-06 133 ADVERSE EVENT
#> 39 2020-11-06 15:43:55 DISCONTINUED DISCONTINUED 2020-11-06 133 ADVERSE EVENT
#> 40 2020-11-06 15:43:55 DISCONTINUED DISCONTINUED 2020-11-06 133 ADVERSE EVENT
#> 41 2020-11-06 15:43:55 DISCONTINUED DISCONTINUED 2020-11-06 133 ADVERSE EVENT
#> 42 2020-11-06 15:43:55 DISCONTINUED DISCONTINUED 2020-11-06 133 ADVERSE EVENT
#> 43 2021-09-21 14:03:42 COMPLETED COMPLETED 2021-09-21 731 <NA>
#> 44 2021-09-21 14:03:42 COMPLETED COMPLETED 2021-09-21 731 <NA>
#> 45 2021-09-21 14:03:42 COMPLETED COMPLETED 2021-09-21 731 <NA>
#> 46 2021-09-21 14:03:42 COMPLETED COMPLETED 2021-09-21 731 <NA>
#> 47 2021-09-21 14:03:42 COMPLETED COMPLETED 2021-09-21 731 <NA>
#> 48 2021-09-21 14:03:42 COMPLETED COMPLETED 2021-09-21 731 <NA>
#> 49 2021-09-21 14:03:42 COMPLETED COMPLETED 2021-09-21 731 <NA>
#> 50 2022-08-29 08:20:33 COMPLETED COMPLETED 2022-08-29 731 <NA>
#> 51 2022-08-29 08:20:33 COMPLETED COMPLETED 2022-08-29 731 <NA>
#> 52 2022-08-29 08:20:33 COMPLETED COMPLETED 2022-08-29 731 <NA>
#> 53 2022-08-29 08:20:33 COMPLETED COMPLETED 2022-08-29 731 <NA>
#> 54 2022-08-29 08:20:33 COMPLETED COMPLETED 2022-08-29 731 <NA>
#> 55 2022-08-29 08:20:33 COMPLETED COMPLETED 2022-08-29 731 <NA>
#> 56 2022-08-29 08:20:33 COMPLETED COMPLETED 2022-08-29 731 <NA>
#> 57 2021-01-30 03:55:51 DISCONTINUED DISCONTINUED 2021-01-30 96 DEATH
#> 58 2021-01-30 03:55:51 DISCONTINUED DISCONTINUED 2021-01-30 96 DEATH
#> 59 2021-01-30 03:55:51 DISCONTINUED DISCONTINUED 2021-01-30 96 DEATH
#> 60 2021-01-30 03:55:51 DISCONTINUED DISCONTINUED 2021-01-30 96 DEATH
#> 61 2021-01-30 03:55:51 DISCONTINUED DISCONTINUED 2021-01-30 96 DEATH
#> 62 2021-01-30 03:55:51 DISCONTINUED DISCONTINUED 2021-01-30 96 DEATH
#> 63 2021-01-30 03:55:51 DISCONTINUED DISCONTINUED 2021-01-30 96 DEATH
#> 64 2021-10-17 05:34:26 COMPLETED COMPLETED 2021-10-17 731 <NA>
#> 65 2021-10-17 05:34:26 COMPLETED COMPLETED 2021-10-17 731 <NA>
#> 66 2021-10-17 05:34:26 COMPLETED COMPLETED 2021-10-17 731 <NA>
#> 67 2021-10-17 05:34:26 COMPLETED COMPLETED 2021-10-17 731 <NA>
#> 68 2021-10-17 05:34:26 COMPLETED COMPLETED 2021-10-17 731 <NA>
#> 69 2021-10-17 05:34:26 COMPLETED COMPLETED 2021-10-17 731 <NA>
#> 70 2021-10-17 05:34:26 COMPLETED COMPLETED 2021-10-17 731 <NA>
#> DTHDT DTHCAUS DTHCAT LDDTHELD LDDTHGR1 LSTALVDT DTHADY
#> 1 <NA> <NA> <NA> NA <NA> 2023-02-15 NA
#> 2 <NA> <NA> <NA> NA <NA> 2023-02-15 NA
#> 3 <NA> <NA> <NA> NA <NA> 2023-02-15 NA
#> 4 <NA> <NA> <NA> NA <NA> 2023-02-15 NA
#> 5 <NA> <NA> <NA> NA <NA> 2023-02-15 NA
#> 6 <NA> <NA> <NA> NA <NA> 2023-02-15 NA
#> 7 <NA> <NA> <NA> NA <NA> 2023-02-15 NA
#> 8 <NA> <NA> <NA> NA <NA> <NA> NA
#> 9 <NA> <NA> <NA> NA <NA> <NA> NA
#> 10 <NA> <NA> <NA> NA <NA> <NA> NA
#> 11 <NA> <NA> <NA> NA <NA> <NA> NA
#> 12 <NA> <NA> <NA> NA <NA> <NA> NA
#> 13 <NA> <NA> <NA> NA <NA> <NA> NA
#> 14 <NA> <NA> <NA> NA <NA> <NA> NA
#> 15 <NA> <NA> <NA> NA <NA> 2022-05-25 NA
#> 16 <NA> <NA> <NA> NA <NA> 2022-05-25 NA
#> 17 <NA> <NA> <NA> NA <NA> 2022-05-25 NA
#> 18 <NA> <NA> <NA> NA <NA> 2022-05-25 NA
#> 19 <NA> <NA> <NA> NA <NA> 2022-05-25 NA
#> 20 <NA> <NA> <NA> NA <NA> 2022-05-25 NA
#> 21 <NA> <NA> <NA> NA <NA> 2022-05-25 NA
#> 22 2021-01-23 ADVERSE EVENT ADVERSE EVENT 1 <=30 2021-01-23 332
#> 23 2021-01-23 ADVERSE EVENT ADVERSE EVENT 1 <=30 2021-01-23 332
#> 24 2021-01-23 ADVERSE EVENT ADVERSE EVENT 1 <=30 2021-01-23 332
#> 25 2021-01-23 ADVERSE EVENT ADVERSE EVENT 1 <=30 2021-01-23 332
#> 26 2021-01-23 ADVERSE EVENT ADVERSE EVENT 1 <=30 2021-01-23 332
#> 27 2021-01-23 ADVERSE EVENT ADVERSE EVENT 1 <=30 2021-01-23 332
#> 28 2021-01-23 ADVERSE EVENT ADVERSE EVENT 1 <=30 2021-01-23 332
#> 29 <NA> <NA> <NA> NA <NA> 2021-04-10 NA
#> 30 <NA> <NA> <NA> NA <NA> 2021-04-10 NA
#> 31 <NA> <NA> <NA> NA <NA> 2021-04-10 NA
#> 32 <NA> <NA> <NA> NA <NA> 2021-04-10 NA
#> 33 <NA> <NA> <NA> NA <NA> 2021-04-10 NA
#> 34 <NA> <NA> <NA> NA <NA> 2021-04-10 NA
#> 35 <NA> <NA> <NA> NA <NA> 2021-04-10 NA
#> 36 <NA> <NA> <NA> NA <NA> 2020-11-17 NA
#> 37 <NA> <NA> <NA> NA <NA> 2020-11-17 NA
#> 38 <NA> <NA> <NA> NA <NA> 2020-11-17 NA
#> 39 <NA> <NA> <NA> NA <NA> 2020-11-17 NA
#> 40 <NA> <NA> <NA> NA <NA> 2020-11-17 NA
#> 41 <NA> <NA> <NA> NA <NA> 2020-11-17 NA
#> 42 <NA> <NA> <NA> NA <NA> 2020-11-17 NA
#> 43 <NA> <NA> <NA> NA <NA> 2021-10-03 NA
#> 44 <NA> <NA> <NA> NA <NA> 2021-10-03 NA
#> 45 <NA> <NA> <NA> NA <NA> 2021-10-03 NA
#> 46 <NA> <NA> <NA> NA <NA> 2021-10-03 NA
#> 47 <NA> <NA> <NA> NA <NA> 2021-10-03 NA
#> 48 <NA> <NA> <NA> NA <NA> 2021-10-03 NA
#> 49 <NA> <NA> <NA> NA <NA> 2021-10-03 NA
#> 50 <NA> <NA> <NA> NA <NA> 2022-09-10 NA
#> 51 <NA> <NA> <NA> NA <NA> 2022-09-10 NA
#> 52 <NA> <NA> <NA> NA <NA> 2022-09-10 NA
#> 53 <NA> <NA> <NA> NA <NA> 2022-09-10 NA
#> 54 <NA> <NA> <NA> NA <NA> 2022-09-10 NA
#> 55 <NA> <NA> <NA> NA <NA> 2022-09-10 NA
#> 56 <NA> <NA> <NA> NA <NA> 2022-09-10 NA
#> 57 2021-02-24 ADVERSE EVENT ADVERSE EVENT 25 <=30 2021-02-24 121
#> 58 2021-02-24 ADVERSE EVENT ADVERSE EVENT 25 <=30 2021-02-24 121
#> 59 2021-02-24 ADVERSE EVENT ADVERSE EVENT 25 <=30 2021-02-24 121
#> 60 2021-02-24 ADVERSE EVENT ADVERSE EVENT 25 <=30 2021-02-24 121
#> 61 2021-02-24 ADVERSE EVENT ADVERSE EVENT 25 <=30 2021-02-24 121
#> 62 2021-02-24 ADVERSE EVENT ADVERSE EVENT 25 <=30 2021-02-24 121
#> 63 2021-02-24 ADVERSE EVENT ADVERSE EVENT 25 <=30 2021-02-24 121
#> 64 <NA> <NA> <NA> NA <NA> 2021-11-15 NA
#> 65 <NA> <NA> <NA> NA <NA> 2021-11-15 NA
#> 66 <NA> <NA> <NA> NA <NA> 2021-11-15 NA
#> 67 <NA> <NA> <NA> NA <NA> 2021-11-15 NA
#> 68 <NA> <NA> <NA> NA <NA> 2021-11-15 NA
#> 69 <NA> <NA> <NA> NA <NA> 2021-11-15 NA
#> 70 <NA> <NA> <NA> NA <NA> 2021-11-15 NA
#> study_duration_secs AGEGR1 TRTDURD DCSREAS_GRP AEWITHFL
#> 1 63113904 <65 730.48499 <NA> <NA>
#> 2 63113904 <65 730.48499 <NA> <NA>
#> 3 63113904 <65 730.48499 <NA> <NA>
#> 4 63113904 <65 730.48499 <NA> <NA>
#> 5 63113904 <65 730.48499 <NA> <NA>
#> 6 63113904 <65 730.48499 <NA> <NA>
#> 7 63113904 <65 730.48499 <NA> <NA>
#> 8 63113904 <65 NA <NA> <NA>
#> 9 63113904 <65 NA <NA> <NA>
#> 10 63113904 <65 NA <NA> <NA>
#> 11 63113904 <65 NA <NA> <NA>
#> 12 63113904 <65 NA <NA> <NA>
#> 13 63113904 <65 NA <NA> <NA>
#> 14 63113904 <65 NA <NA> <NA>
#> 15 63113904 <65 730.48499 <NA> <NA>
#> 16 63113904 <65 730.48499 <NA> <NA>
#> 17 63113904 <65 730.48499 <NA> <NA>
#> 18 63113904 <65 730.48499 <NA> <NA>
#> 19 63113904 <65 730.48499 <NA> <NA>
#> 20 63113904 <65 730.48499 <NA> <NA>
#> 21 63113904 <65 730.48499 <NA> <NA>
#> 22 63113904 <65 330.83529 Non-Safety N
#> 23 63113904 <65 330.83529 Non-Safety N
#> 24 63113904 <65 330.83529 Non-Safety N
#> 25 63113904 <65 330.83529 Non-Safety N
#> 26 63113904 <65 330.83529 Non-Safety N
#> 27 63113904 <65 330.83529 Non-Safety N
#> 28 63113904 <65 330.83529 Non-Safety N
#> 29 63113904 <65 730.48499 <NA> <NA>
#> 30 63113904 <65 730.48499 <NA> <NA>
#> 31 63113904 <65 730.48499 <NA> <NA>
#> 32 63113904 <65 730.48499 <NA> <NA>
#> 33 63113904 <65 730.48499 <NA> <NA>
#> 34 63113904 <65 730.48499 <NA> <NA>
#> 35 63113904 <65 730.48499 <NA> <NA>
#> 36 63113904 <65 132.45549 Safety Y
#> 37 63113904 <65 132.45549 Safety Y
#> 38 63113904 <65 132.45549 Safety Y
#> 39 63113904 <65 132.45549 Safety Y
#> 40 63113904 <65 132.45549 Safety Y
#> 41 63113904 <65 132.45549 Safety Y
#> 42 63113904 <65 132.45549 Safety Y
#> 43 63113904 <65 730.48499 <NA> <NA>
#> 44 63113904 <65 730.48499 <NA> <NA>
#> 45 63113904 <65 730.48499 <NA> <NA>
#> 46 63113904 <65 730.48499 <NA> <NA>
#> 47 63113904 <65 730.48499 <NA> <NA>
#> 48 63113904 <65 730.48499 <NA> <NA>
#> 49 63113904 <65 730.48499 <NA> <NA>
#> 50 63113904 <65 730.48499 <NA> <NA>
#> 51 63113904 <65 730.48499 <NA> <NA>
#> 52 63113904 <65 730.48499 <NA> <NA>
#> 53 63113904 <65 730.48499 <NA> <NA>
#> 54 63113904 <65 730.48499 <NA> <NA>
#> 55 63113904 <65 730.48499 <NA> <NA>
#> 56 63113904 <65 730.48499 <NA> <NA>
#> 57 63113904 <65 95.23569 Non-Safety N
#> 58 63113904 <65 95.23569 Non-Safety N
#> 59 63113904 <65 95.23569 Non-Safety N
#> 60 63113904 <65 95.23569 Non-Safety N
#> 61 63113904 <65 95.23569 Non-Safety N
#> 62 63113904 <65 95.23569 Non-Safety N
#> 63 63113904 <65 95.23569 Non-Safety N
#> 64 63113904 <65 730.48499 <NA> <NA>
#> 65 63113904 <65 730.48499 <NA> <NA>
#> 66 63113904 <65 730.48499 <NA> <NA>
#> 67 63113904 <65 730.48499 <NA> <NA>
#> 68 63113904 <65 730.48499 <NA> <NA>
#> 69 63113904 <65 730.48499 <NA> <NA>
#> 70 63113904 <65 730.48499 <NA> <NA>
#> PARAM PARAMCD AVISIT
#> 1 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 2 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 3 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 4 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 5 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 6 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 7 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 8 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 9 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 10 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 11 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 12 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 13 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 14 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 15 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 16 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 17 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 18 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 19 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 20 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 21 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 22 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 23 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 24 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 25 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 26 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 27 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 28 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 29 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 30 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 31 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 32 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 33 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 34 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 35 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 36 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 37 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 38 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 39 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 40 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 41 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 42 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 43 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 44 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 45 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 46 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 47 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 48 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 49 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 50 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 51 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 52 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 53 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 54 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 55 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 56 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 57 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> 58 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 59 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 60 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 61 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 62 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 63 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 64 Sum of Longest Diameter by Investigator SLDINV POST-BASELINE MINIMUM
#> 65 Sum of Longest Diameter by Investigator SLDINV END OF INDUCTION
#> 66 Sum of Longest Diameter by Investigator SLDINV CYCLE 4 DAY 1
#> 67 Sum of Longest Diameter by Investigator SLDINV FOLLOW UP
#> 68 Sum of Longest Diameter by Investigator SLDINV SCREENING
#> 69 Sum of Longest Diameter by Investigator SLDINV CYCLE 2 DAY 1
#> 70 Sum of Longest Diameter by Investigator SLDINV BASELINE
#> AVISITN ADTM ADY DTYPE AVAL AVALC AVALU
#> 1 999 2021-12-31 00:00:00 348 91.02365 91.0236527565802 mm
#> 2 999 2021-12-31 00:00:00 348 MINIMUM 91.02365 91.0236527565802 mm
#> 3 -1 2020-10-09 00:00:00 -100 124.85139 124.851385571939 mm
#> 4 0 2021-01-17 22:43:53 0 NA <NA> mm
#> 5 2 2021-08-08 00:00:00 203 133.13259 133.132588399725 mm
#> 6 4 2021-10-07 00:00:00 263 188.27147 188.271465355528 mm
#> 7 999 2021-10-16 00:00:00 272 118.57282 118.572821190151 mm
#> 8 999 2021-04-28 00:00:00 463 96.35273 96.3527337970544 mm
#> 9 4 <NA> NA 200.14856 200.14856301978 mm
#> 10 999 2021-06-05 00:00:00 501 210.93728 210.937275562657 mm
#> 11 999 2021-04-28 00:00:00 463 MINIMUM 96.35273 96.3527337970544 mm
#> 12 0 2020-01-21 10:19:08 0 NA <NA> mm
#> 13 2 2021-05-14 00:00:00 479 184.17689 184.176894082022 mm
#> 14 -1 2019-10-13 00:00:00 -100 140.31087 140.310867187201 mm
#> 15 4 2022-03-16 00:00:00 683 125.40015 125.400146831514 mm
#> 16 999 2021-02-14 00:00:00 288 MINIMUM 90.03459 90.0345901510763 mm
#> 17 -1 2020-01-23 00:00:00 -100 128.90567 128.905670010183 mm
#> 18 2 2022-01-15 00:00:00 623 165.18704 165.187043924422 mm
#> 19 999 2021-02-14 00:00:00 288 90.03459 90.0345901510763 mm
#> 20 0 2020-05-02 02:28:45 0 NA <NA> mm
#> 21 999 2021-11-18 00:00:00 565 135.62122 135.621222256451 mm
#> 22 0 2020-02-26 18:15:59 0 NA <NA> mm
#> 23 -1 2019-11-18 00:00:00 -100 152.52540 152.525397129667 mm
#> 24 999 2020-07-18 00:00:00 143 163.04543 163.045432845081 mm
#> 25 2 2020-10-20 00:00:00 237 122.36173 122.361730034768 mm
#> 26 999 2020-04-10 00:00:00 44 145.75018 145.750175731918 mm
#> 27 2 2020-10-20 00:00:00 237 MINIMUM 122.36173 122.361730034768 mm
#> 28 4 2020-12-19 00:00:00 297 159.91349 159.913485103959 mm
#> 29 2 2020-03-11 00:00:00 349 189.10537 189.105366972668 mm
#> 30 4 2020-05-10 00:00:00 409 173.15369 173.153693266196 mm
#> 31 0 2019-03-28 12:07:16 0 NA <NA> mm
#> 32 999 2020-05-29 00:00:00 428 107.69885 107.698849780089 mm
#> 33 999 2020-05-29 00:00:00 428 MINIMUM 107.69885 107.698849780089 mm
#> 34 999 2020-04-20 00:00:00 389 181.57577 181.575767859229 mm
#> 35 -1 2018-12-18 00:00:00 -100 148.38832 148.388321219484 mm
#> 36 2 2020-08-06 00:00:00 40 133.99884 133.998835723584 mm
#> 37 999 2020-11-02 00:00:00 128 204.66368 204.663675562607 mm
#> 38 999 2020-08-13 00:00:00 47 83.76241 83.7624066358607 mm
#> 39 0 2020-06-27 04:48:00 0 NA <NA> mm
#> 40 999 2020-08-13 00:00:00 47 MINIMUM 83.76241 83.7624066358607 mm
#> 41 4 2020-10-05 00:00:00 100 108.83192 108.831916465708 mm
#> 42 -1 2020-03-19 00:00:00 -100 179.87954 179.879537693333 mm
#> 43 2 2021-07-13 00:00:00 660 MINIMUM 138.39151 138.391511890652 mm
#> 44 999 2021-03-23 00:00:00 548 200.43465 200.434648673004 mm
#> 45 0 2019-09-22 02:25:18 0 NA <NA> mm
#> 46 999 2020-05-04 00:00:00 225 198.01173 198.011725546186 mm
#> 47 -1 2019-06-14 00:00:00 -100 130.39820 130.398197675437 mm
#> 48 2 2021-07-13 00:00:00 660 138.39151 138.391511890652 mm
#> 49 4 2021-09-11 00:00:00 720 161.60085 161.600849239382 mm
#> 50 -1 2020-05-20 00:00:00 -100 114.49181 114.491808353182 mm
#> 51 2 2021-11-22 00:00:00 451 104.61988 104.61987615837 mm
#> 52 4 2022-01-21 00:00:00 511 112.40685 112.406853018924 mm
#> 53 0 2020-08-28 20:42:09 0 NA <NA> mm
#> 54 2 2021-11-22 00:00:00 451 MINIMUM 104.61988 104.61987615837 mm
#> 55 999 2022-06-26 00:00:00 667 150.22938 150.229376163983 mm
#> 56 999 2022-03-06 00:00:00 555 208.78071 208.780712314368 mm
#> 57 0 2020-10-26 22:16:26 0 NA <NA> mm
#> 58 -1 2020-07-18 00:00:00 -100 124.72154 124.721544072311 mm
#> 59 999 2020-12-15 00:00:00 50 140.57184 140.571840594842 mm
#> 60 999 2021-01-29 00:00:00 95 127.51110 127.511097135508 mm
#> 61 999 2021-01-29 00:00:00 95 MINIMUM 127.51110 127.511097135508 mm
#> 62 2 2020-11-09 00:00:00 14 182.23378 182.233782192385 mm
#> 63 4 2021-01-08 00:00:00 74 157.81794 157.817935052765 mm
#> 64 999 2020-09-13 00:00:00 332 MINIMUM 137.35879 137.358792827839 mm
#> 65 999 2020-11-08 00:00:00 388 139.47497 139.474967305564 mm
#> 66 4 2020-05-29 00:00:00 225 210.26061 210.260613477461 mm
#> 67 999 2020-09-13 00:00:00 332 137.35879 137.358792827839 mm
#> 68 -1 2019-07-09 00:00:00 -100 124.13405 124.134050109426 mm
#> 69 2 2020-03-30 00:00:00 165 178.19760 178.197602328401 mm
#> 70 0 2019-10-17 17:56:02 0 NA <NA> mm
#> BASE ABLFL CHG PCHG ONTRTFL ANL01FL ANL02FL ANL03FL
#> 1 211.98904 -120.9653879 -57.0620951 Y Y Y
#> 2 211.98904 -120.9653879 -57.0620951 Y Y
#> 3 211.98904 NA NA
#> 4 211.98904 Y NA NA Y Y Y
#> 5 211.98904 -78.8564523 -37.1983627 Y Y
#> 6 211.98904 -23.7175753 -11.1881139 Y Y
#> 7 211.98904 -93.4162195 -44.0665325 Y Y
#> 8 178.07588 -81.7231420 -45.8923151 Y Y
#> 9 178.07588 22.0726872 12.3951024 Y Y
#> 10 178.07588 32.8613998 18.4535944 Y Y Y
#> 11 178.07588 -81.7231420 -45.8923151 Y Y
#> 12 178.07588 Y NA NA Y Y Y
#> 13 178.07588 6.1010183 3.4260779 Y Y
#> 14 178.07588 NA NA
#> 15 154.74494 -29.3447960 -18.9633312 Y Y Y
#> 16 154.74494 -64.7103527 -41.8174265 Y Y
#> 17 154.74494 NA NA
#> 18 154.74494 10.4421010 6.7479433 Y Y
#> 19 154.74494 -64.7103527 -41.8174265 Y Y
#> 20 154.74494 Y NA NA Y Y Y
#> 21 154.74494 -19.1237206 -12.3582201 Y Y
#> 22 123.13540 Y NA NA Y Y Y
#> 23 123.13540 NA NA
#> 24 123.13540 39.9100312 32.4115004 Y Y
#> 25 123.13540 -0.7736716 -0.6283097 Y Y
#> 26 123.13540 22.6147741 18.3657776 Y Y
#> 27 123.13540 -0.7736716 -0.6283097 Y Y
#> 28 123.13540 36.7780834 29.8680013 Y Y Y
#> 29 122.78669 66.3186782 54.0112930 Y Y
#> 30 122.78669 50.3670045 41.0199225 Y Y
#> 31 122.78669 Y NA NA Y Y Y
#> 32 122.78669 -15.0878390 -12.2878458 Y Y Y
#> 33 122.78669 -15.0878390 -12.2878458 Y Y
#> 34 122.78669 58.7890791 47.8790329 Y Y
#> 35 122.78669 NA NA
#> 36 99.12705 34.8717828 35.1788758 Y Y
#> 37 99.12705 105.5366227 106.4660147 Y Y Y
#> 38 99.12705 -15.3646463 -15.4999527 Y Y
#> 39 99.12705 Y NA NA Y Y Y
#> 40 99.12705 -15.3646463 -15.4999527 Y Y
#> 41 99.12705 9.7048636 9.7903280 Y Y
#> 42 99.12705 NA NA
#> 43 141.45956 -3.0680515 -2.1688541 Y Y
#> 44 141.45956 58.9750853 41.6904194 Y Y
#> 45 141.45956 Y NA NA Y Y Y
#> 46 141.45956 56.5521621 39.9776168 Y Y
#> 47 141.45956 NA NA
#> 48 141.45956 -3.0680515 -2.1688541 Y Y
#> 49 141.45956 20.1412858 14.2381931 Y Y Y
#> 50 109.24628 NA NA
#> 51 109.24628 -4.6264062 -4.2348409 Y Y
#> 52 109.24628 3.1605706 2.8930693 Y Y
#> 53 109.24628 Y NA NA Y Y Y
#> 54 109.24628 -4.6264062 -4.2348409 Y Y
#> 55 109.24628 40.9830938 37.5144059 Y Y Y
#> 56 109.24628 99.5344299 91.1101300 Y Y
#> 57 131.96520 Y NA NA Y Y Y
#> 58 131.96520 NA NA
#> 59 131.96520 8.6066437 6.5219042 Y Y
#> 60 131.96520 -4.4540997 -3.3752079 Y Y Y
#> 61 131.96520 -4.4540997 -3.3752079 Y Y
#> 62 131.96520 50.2685853 38.0923051 Y Y
#> 63 131.96520 25.8527382 19.5905730 Y Y
#> 64 211.44121 -74.0824163 -35.0368864 Y Y
#> 65 211.44121 -71.9662418 -34.0360529 Y Y Y
#> 66 211.44121 -1.1805956 -0.5583564 Y Y
#> 67 211.44121 -74.0824163 -35.0368864 Y Y
#> 68 211.44121 NA NA
#> 69 211.44121 -33.2436068 -15.7223878 Y Y
#> 70 211.44121 Y NA NA Y Y Y