Time to Adverse Event Analysis Dataset (ADAETTE) — radaette • random.cdisc.data

Function to generate random time to AE dataset for a given subject-level analysis dataset.

radaette(
  ADSL,
  event.descr = NULL,
  censor.descr = NULL,
  lookup = NULL,
  seed = NULL,
  na_percentage = 0,
  na_vars = list(CNSR = c(NA, 0.1), AVAL = c(1234, 0.1)),
  cached = FALSE
)

Arguments

ADSL

Subject-Level Analysis Dataset (ADSL).

event.descr

Character vector with description of events.

censor.descr

Character vector with description of censors.

lookup

Data.frame containing additional parameters.

seed

Seed for random number generation.

na_percentage

(numeric) Default percentage of values to be replaced by NA

na_vars

(list) A named list where the name of each element is a column name of ds. Each element of this list should be a numeric vector with two elements

seed The seed to be used for this element - can be left NA
percentage How many element should be replaced. 0 is 0 % 1 is 100 %, can be left NA and default percentage is used. This will overwrite default percentage (percentage argument))

cached

boolean whether the cached ADAETTE data cadaette should be returned or new data should be generated. If set to TRUE then the other arguments to radaette will be ignored.

Value

data.frame

Details

Keys: STUDYID USUBJID PARAMCD

Author

Xiuting Mi

Examples

library(random.cdisc.data)
ADSL <- suppressWarnings(radsl(N = 10, seed = 1, study_duration = 2))
radaette(ADSL, seed = 2)
#> # A tibble: 90 × 55
#>    STUDYID USUBJID    SUBJID SITEID   AGE AGEU  SEX   RACE  ETHNIC COUNTRY DTHFL
#>    <chr>   <chr>      <chr>  <chr>  <int> <fct> <fct> <fct> <fct>  <fct>   <fct>
#>  1 AB12345 AB12345-B… id-9   BRA-1     35 YEARS F     BLAC… NOT H… BRA     N    
#>  2 AB12345 AB12345-B… id-9   BRA-1     35 YEARS F     BLAC… NOT H… BRA     N    
#>  3 AB12345 AB12345-B… id-9   BRA-1     35 YEARS F     BLAC… NOT H… BRA     N    
#>  4 AB12345 AB12345-B… id-9   BRA-1     35 YEARS F     BLAC… NOT H… BRA     N    
#>  5 AB12345 AB12345-B… id-9   BRA-1     35 YEARS F     BLAC… NOT H… BRA     N    
#>  6 AB12345 AB12345-B… id-9   BRA-1     35 YEARS F     BLAC… NOT H… BRA     N    
#>  7 AB12345 AB12345-B… id-9   BRA-1     35 YEARS F     BLAC… NOT H… BRA     N    
#>  8 AB12345 AB12345-B… id-9   BRA-1     35 YEARS F     BLAC… NOT H… BRA     N    
#>  9 AB12345 AB12345-B… id-9   BRA-1     35 YEARS F     BLAC… NOT H… BRA     N    
#> 10 AB12345 AB12345-B… id-8   BRA-9     31 YEARS F     ASIAN NOT H… BRA     N    
#> # … with 80 more rows, and 44 more variables: INVID <chr>, INVNAM <chr>,
#> #   ARM <fct>, ARMCD <fct>, ACTARM <fct>, ACTARMCD <fct>, TRT01P <fct>,
#> #   TRT01A <fct>, REGION1 <fct>, STRATA1 <fct>, STRATA2 <fct>, BMRKR1 <dbl>,
#> #   BMRKR2 <fct>, ITTFL <fct>, SAFFL <fct>, BMEASIFL <fct>, BEP01FL <fct>,
#> #   RANDDT <date>, TRTSDTM <dttm>, TRTEDTM <dttm>, EOSSTT <fct>, EOTSTT <fct>,
#> #   EOSDT <date>, EOSDY <int>, DCSREAS <fct>, DTHDT <date>, DTHCAUS <fct>,
#> #   DTHCAT <fct>, LDDTHELD <int>, LDDTHGR1 <fct>, LSTALVDT <date>, …