NEST  Accelerating Clinical Reporting

NEST is a collection of open-sourced R packages, which enables faster and more efficient insights generation under clinical research settings, for both exploratory and regulatory purposes.

NEST was originally developed at Roche. Since open-sourced, it has attracted many collaborators through efforts such as pharmaverse. With the vision of accelerating clinical reporting, we welcome new collaborators from academia, pharmaceutical industry, as well as clinical research institutes.

More about NEST
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NEST on GitHub

NEST Products

Packages and products under NEST cover a variety of needs for clinical reporting, ranging from generation of regulatory-required tables, listings and graphs (TLGs), to creation of interactive dashboard for data exploration.

NEST Timeline


Here, you can learn about important milestones NEST has achieved so far, and get a preview of key products and features that will become available in the near future.

  1. The first PoC version of {teal} was launched. {teal} is one of the key and foundational components that later formed the NEST project.
  2. {rtables} PoC was presented at BaselR event, followed by the launch of first versions of {rtables}, {tern}, {teal.oncology}, {random.cdisc.data}.
  3. Workshop on {rtables} and numerous talks about NEST were presented at the first RinPharma conference.
  4. NEST project got funded at Roche PD Data Sciences (formally Biometrics). A team of full time developers was established.
  5. The first official release of NEST packages and TLG-Catalog to the Roche internal exploratory computing environment.
  6. NEST packages successfully went through the internal validation process and was allowed to be used in the regulatory computing environment.
  7. The first CRAN release of {rtables}, followed by open source of the codebase which kicked off collaborations with other pharma companies.
  8. NEST project was internally recognised by winning the Roche PD Breakthrough Award, and it was used to support the first R-based submission to FDA.
  9. {formatters} and {tern} were released to CRAN, and a PoC version of {rlistings} was launched.
  10. - NEST was highlighted at various external events, including RConsortium Webinar, PHUSE US Event, and several UseR! Events.
    - TLG-Catalog is open-sourced.
  11. The industry collaborative effort {falcon}, which aims to promote harmonized TLG layouts for clinical reporting, is expected to be released to CRAN.
  12. - A CRAN release of {teal} is planned, with a redesigned and enhanced filter panel.
    - {falcon} will be presented at PHUSE EU Event.
  13. - Launch & open source the package {cardinal} for analysis result data (ARD)
    - More exciting features in various NEST packages

How NEST Operates

A set of operating principles guide NEST team to keep innovating and delivering high-quality products to users.

User Centric

NEST's development priorities are driven by our users needs and business benefits.

Agile Development

NEST is composed of four product teams, which all apply Scale Agile Framework in daily activities.

Learn More about NEST

Collaborative

NEST is an open-source project, which so far has attracted 100+ developers to collaborate.

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