Typical use is tabulating changes from baseline
measurement of an Analysis Variable.
tbl_baseline_chg(
data,
baseline_level,
denominator,
by = NULL,
digits = NULL,
id = "USUBJID",
visit = "AVISIT",
visit_number = "AVISITN",
analysis_variable = "AVAL",
change_variable = "CHG"
)
# S3 method for class 'tbl_baseline_chg'
add_overall(
x,
last = FALSE,
col_label = "All Participants \n(N = {gtsummary::style_number(n)})",
...
)
Arguments
- data
(data.frame)
A data frame.
- baseline_level
(string)
String identifying baseline level in the visit variable.
- denominator
(string)
Data set used to compute the header counts (typically ADSL).
- by
(tidy-select)
A single column from data. Summary statistics will be stratified by this variable.
Default is NULL.
- digits
(formula-list-selector)
Specifies how summary statistics are rounded. Values may be either integer(s)
or function(s). If not specified, default formatting is assigned
via assign_summary_digits(). See below for details.
- id
(string)
String identifying the unique subjects. Default is 'USUBJID'.
- visit
(string)
String for the visit variable. Default is
'AVISIT'. If there are more than one entry for each visit and subject,
only the first row is kept.
- visit_number
(string)
String identifying the visit or analysis sequence number. Default is
'AVISITN'.
- analysis_variable
(string)
String identifying the analysis values. Default is 'AVAL'.
- change_variable
(string)
String identifying the change from baseline values. Default is 'CHG'.
- x
(tbl_summary, tbl_svysummary, tbl_continuous, tbl_custom_summary)
A stratified 'gtsummary' table
- last
(scalar logical)
Logical indicator to display overall column last in table.
Default is FALSE, which will display overall column first.
- col_label
(string)
String indicating the column label. Default is "**Overall** \nN = {style_number(N)}"
- ...
These dots are for future extensions and must be empty.
Examples
theme_gtsummary_roche()
#> Setting theme "Roche"
df <- cards::ADLB |>
dplyr::mutate(AVISIT = trimws(AVISIT)) |>
dplyr::filter(
AVISIT != "End of Treatment",
PARAMCD == "SODIUM"
)
tbl_baseline_chg(
data = df,
baseline_level = "Baseline",
by = "TRTA",
denominator = cards::ADSL
)
#> ℹ Converting column "TRTA" to a factor.
| Visit |
Placebo
(N = 86)
|
Xanomeline High Dose
(N = 84)
|
Xanomeline Low Dose
(N = 84)
|
|---|
| Value at Visit |
Change from Baseline |
Value at Visit |
Change from Baseline |
Value at Visit |
Change from Baseline |
|---|
| Baseline |
|
|
|
|
|
|
| n |
7 |
|
7 |
|
6 |
|
| Mean (SD) |
141.14 (1.46) |
|
139.14 (2.19) |
|
139.50 (4.23) |
|
| Median |
141.00 |
|
139.00 |
|
138.50 |
|
| Min - Max |
140.00 - 144.00 |
|
136.00 - 142.00 |
|
134.00 - 145.00 |
|
| Week 2 |
|
|
|
|
|
|
| n |
7 |
7 |
6 |
6 |
6 |
6 |
| Mean (SD) |
140.57 (1.62) |
-0.6 (1.9) |
138.83 (3.25) |
0.2 (3.5) |
139.50 (2.35) |
0.0 (3.7) |
| Median |
141.00 |
-1.0 |
140.50 |
0.5 |
139.50 |
-0.5 |
| Min - Max |
138.00 - 142.00 |
-3.0 - 2.0 |
133.00 - 141.00 |
-5.0 - 5.0 |
136.00 - 142.00 |
-5.0 - 5.0 |
| Week 4 |
|
|
|
|
|
|
| n |
7 |
7 |
6 |
6 |
5 |
5 |
| Mean (SD) |
139.29 (2.81) |
-1.86 (2.54) |
139.83 (3.54) |
1.17 (2.04) |
139.40 (1.34) |
-0.60 (3.51) |
| Median |
140.00 |
-1.00 |
138.50 |
0.00 |
140.00 |
0.00 |
| Min - Max |
134.00 - 142.00 |
-7.00 - 0.00 |
138.00 - 147.00 |
0.00 - 5.00 |
138.00 - 141.00 |
-5.00 - 4.00 |
| Week 6 |
|
|
|
|
|
|
| n |
5 |
5 |
6 |
6 |
4 |
4 |
| Mean (SD) |
140.00 (1.87) |
-0.40 (1.67) |
139.67 (1.97) |
1.00 (2.28) |
140.50 (2.65) |
1.75 (5.38) |
| Median |
140.00 |
0.00 |
139.00 |
0.50 |
140.00 |
2.50 |
| Min - Max |
138.00 - 143.00 |
-2.00 - 2.00 |
138.00 - 143.00 |
-1.00 - 5.00 |
138.00 - 144.00 |
-5.00 - 7.00 |
| Week 8 |
|
|
|
|
|
|
| n |
5 |
5 |
4 |
4 |
3 |
3 |
| Mean (SD) |
140.60 (1.52) |
0.20 (1.64) |
139.00 (2.16) |
-0.50 (2.38) |
139.00 (2.65) |
0.00 (3.46) |
| Median |
141.00 |
1.00 |
139.50 |
-0.50 |
140.00 |
2.00 |
| Min - Max |
139.00 - 142.00 |
-2.00 - 2.00 |
136.00 - 141.00 |
-3.00 - 2.00 |
136.00 - 141.00 |
-4.00 - 2.00 |
| Week 12 |
|
|
|
|
|
|
| n |
5 |
5 |
4 |
4 |
2 |
2 |
| Mean (SD) |
141.00 (1.58) |
0.60 (1.14) |
140.75 (2.99) |
1.25 (1.26) |
139.00 (0.00) |
0.00 (7.07) |
| Median |
141.00 |
1.00 |
140.00 |
1.00 |
139.00 |
0.00 |
| Min - Max |
139.00 - 143.00 |
-1.00 - 2.00 |
138.00 - 145.00 |
0.00 - 3.00 |
139.00 - 139.00 |
-5.00 - 5.00 |
| Week 16 |
|
|
|
|
|
|
| n |
5 |
5 |
4 |
4 |
2 |
2 |
| Mean (SD) |
140.80 (1.10) |
0.40 (0.89) |
142.00 (3.56) |
2.50 (1.91) |
139.50 (0.71) |
0.50 (6.36) |
| Median |
141.00 |
1.00 |
141.00 |
2.00 |
139.50 |
0.50 |
| Min - Max |
139.00 - 142.00 |
-1.00 - 1.00 |
139.00 - 147.00 |
1.00 - 5.00 |
139.00 - 140.00 |
-4.00 - 5.00 |
| Week 20 |
|
|
|
|
|
|
| n |
5 |
5 |
4 |
4 |
2 |
2 |
| Mean (SD) |
141.60 (1.67) |
1.20 (1.92) |
138.75 (3.59) |
-0.75 (2.22) |
137.50 (0.71) |
-1.50 (6.36) |
| Median |
142.00 |
2.00 |
137.50 |
-1.00 |
137.50 |
-1.50 |
| Min - Max |
139.00 - 143.00 |
-2.00 - 3.00 |
136.00 - 144.00 |
-3.00 - 2.00 |
137.00 - 138.00 |
-6.00 - 3.00 |
| Week 24 |
|
|
|
|
|
|
| n |
5 |
5 |
4 |
4 |
2 |
2 |
| Mean (SD) |
140.40 (1.14) |
0.00 (1.22) |
139.25 (3.59) |
-0.25 (2.63) |
138.00 (2.83) |
-1.00 (4.24) |
| Median |
140.00 |
0.00 |
140.50 |
0.50 |
138.00 |
-1.00 |
| Min - Max |
139.00 - 142.00 |
-2.00 - 1.00 |
134.00 - 142.00 |
-4.00 - 2.00 |
136.00 - 140.00 |
-4.00 - 2.00 |
| Week 26 |
|
|
|
|
|
|
| n |
5 |
5 |
4 |
4 |
2 |
2 |
| Mean (SD) |
140.60 (2.51) |
0.20 (2.77) |
138.75 (4.57) |
-0.75 (2.87) |
142.50 (2.12) |
3.50 (4.95) |
| Median |
140.00 |
-1.00 |
138.00 |
-1.00 |
142.50 |
3.50 |
| Min - Max |
139.00 - 145.00 |
-2.00 - 5.00 |
134.00 - 145.00 |
-4.00 - 3.00 |
141.00 - 144.00 |
0.00 - 7.00 |
| Visit |
Placebo
(N = 86)
|
Xanomeline High Dose
(N = 84)
|
Xanomeline Low Dose
(N = 84)
|
All Participants
|
|---|
| Value at Visit |
Change from Baseline |
Value at Visit |
Change from Baseline |
Value at Visit |
Change from Baseline |
Value at Visit |
Change from Baseline |
|---|
| Baseline |
|
|
|
|
|
|
|
|
| n |
7 |
|
7 |
|
6 |
|
20 |
|
| Mean (SD) |
141.14 (1.46) |
|
139.14 (2.19) |
|
139.50 (4.23) |
|
139.95 (2.78) |
|
| Median |
141.00 |
|
139.00 |
|
138.50 |
|
140.00 |
|
| Min - Max |
140.00 - 144.00 |
|
136.00 - 142.00 |
|
134.00 - 145.00 |
|
134.00 - 145.00 |
|
| Week 2 |
|
|
|
|
|
|
|
|
| n |
7 |
7 |
6 |
6 |
6 |
6 |
19 |
19 |
| Mean (SD) |
140.57 (1.62) |
-0.6 (1.9) |
138.83 (3.25) |
0.2 (3.5) |
139.50 (2.35) |
0.0 (3.7) |
139.68 (2.43) |
-0.2 (2.9) |
| Median |
141.00 |
-1.0 |
140.50 |
0.5 |
139.50 |
-0.5 |
140.00 |
-1.0 |
| Min - Max |
138.00 - 142.00 |
-3.0 - 2.0 |
133.00 - 141.00 |
-5.0 - 5.0 |
136.00 - 142.00 |
-5.0 - 5.0 |
133.00 - 142.00 |
-5.0 - 5.0 |
| Week 4 |
|
|
|
|
|
|
|
|
| n |
7 |
7 |
6 |
6 |
5 |
5 |
18 |
18 |
| Mean (SD) |
139.29 (2.81) |
-1.86 (2.54) |
139.83 (3.54) |
1.17 (2.04) |
139.40 (1.34) |
-0.60 (3.51) |
139.50 (2.64) |
-0.50 (2.85) |
| Median |
140.00 |
-1.00 |
138.50 |
0.00 |
140.00 |
0.00 |
139.50 |
0.00 |
| Min - Max |
134.00 - 142.00 |
-7.00 - 0.00 |
138.00 - 147.00 |
0.00 - 5.00 |
138.00 - 141.00 |
-5.00 - 4.00 |
134.00 - 147.00 |
-7.00 - 5.00 |
| Week 6 |
|
|
|
|
|
|
|
|
| n |
5 |
5 |
6 |
6 |
4 |
4 |
15 |
15 |
| Mean (SD) |
140.00 (1.87) |
-0.40 (1.67) |
139.67 (1.97) |
1.00 (2.28) |
140.50 (2.65) |
1.75 (5.38) |
140.00 (2.00) |
0.73 (3.10) |
| Median |
140.00 |
0.00 |
139.00 |
0.50 |
140.00 |
2.50 |
139.00 |
0.00 |
| Min - Max |
138.00 - 143.00 |
-2.00 - 2.00 |
138.00 - 143.00 |
-1.00 - 5.00 |
138.00 - 144.00 |
-5.00 - 7.00 |
138.00 - 144.00 |
-5.00 - 7.00 |
| Week 8 |
|
|
|
|
|
|
|
|
| n |
5 |
5 |
4 |
4 |
3 |
3 |
12 |
12 |
| Mean (SD) |
140.60 (1.52) |
0.20 (1.64) |
139.00 (2.16) |
-0.50 (2.38) |
139.00 (2.65) |
0.00 (3.46) |
139.67 (2.02) |
-0.08 (2.19) |
| Median |
141.00 |
1.00 |
139.50 |
-0.50 |
140.00 |
2.00 |
140.00 |
1.00 |
| Min - Max |
139.00 - 142.00 |
-2.00 - 2.00 |
136.00 - 141.00 |
-3.00 - 2.00 |
136.00 - 141.00 |
-4.00 - 2.00 |
136.00 - 142.00 |
-4.00 - 2.00 |
| Week 12 |
|
|
|
|
|
|
|
|
| n |
5 |
5 |
4 |
4 |
2 |
2 |
11 |
11 |
| Mean (SD) |
141.00 (1.58) |
0.60 (1.14) |
140.75 (2.99) |
1.25 (1.26) |
139.00 (0.00) |
0.00 (7.07) |
140.55 (2.07) |
0.73 (2.49) |
| Median |
141.00 |
1.00 |
140.00 |
1.00 |
139.00 |
0.00 |
140.00 |
1.00 |
| Min - Max |
139.00 - 143.00 |
-1.00 - 2.00 |
138.00 - 145.00 |
0.00 - 3.00 |
139.00 - 139.00 |
-5.00 - 5.00 |
138.00 - 145.00 |
-5.00 - 5.00 |
| Week 16 |
|
|
|
|
|
|
|
|
| n |
5 |
5 |
4 |
4 |
2 |
2 |
11 |
11 |
| Mean (SD) |
140.80 (1.10) |
0.40 (0.89) |
142.00 (3.56) |
2.50 (1.91) |
139.50 (0.71) |
0.50 (6.36) |
141.00 (2.28) |
1.18 (2.56) |
| Median |
141.00 |
1.00 |
141.00 |
2.00 |
139.50 |
0.50 |
141.00 |
1.00 |
| Min - Max |
139.00 - 142.00 |
-1.00 - 1.00 |
139.00 - 147.00 |
1.00 - 5.00 |
139.00 - 140.00 |
-4.00 - 5.00 |
139.00 - 147.00 |
-4.00 - 5.00 |
| Week 20 |
|
|
|
|
|
|
|
|
| n |
5 |
5 |
4 |
4 |
2 |
2 |
11 |
11 |
| Mean (SD) |
141.60 (1.67) |
1.20 (1.92) |
138.75 (3.59) |
-0.75 (2.22) |
137.50 (0.71) |
-1.50 (6.36) |
139.82 (2.86) |
0.00 (2.90) |
| Median |
142.00 |
2.00 |
137.50 |
-1.00 |
137.50 |
-1.50 |
139.00 |
1.00 |
| Min - Max |
139.00 - 143.00 |
-2.00 - 3.00 |
136.00 - 144.00 |
-3.00 - 2.00 |
137.00 - 138.00 |
-6.00 - 3.00 |
136.00 - 144.00 |
-6.00 - 3.00 |
| Week 24 |
|
|
|
|
|
|
|
|
| n |
5 |
5 |
4 |
4 |
2 |
2 |
11 |
11 |
| Mean (SD) |
140.40 (1.14) |
0.00 (1.22) |
139.25 (3.59) |
-0.25 (2.63) |
138.00 (2.83) |
-1.00 (4.24) |
139.55 (2.46) |
-0.27 (2.15) |
| Median |
140.00 |
0.00 |
140.50 |
0.50 |
138.00 |
-1.00 |
140.00 |
0.00 |
| Min - Max |
139.00 - 142.00 |
-2.00 - 1.00 |
134.00 - 142.00 |
-4.00 - 2.00 |
136.00 - 140.00 |
-4.00 - 2.00 |
134.00 - 142.00 |
-4.00 - 2.00 |
| Week 26 |
|
|
|
|
|
|
|
|
| n |
5 |
5 |
4 |
4 |
2 |
2 |
11 |
11 |
| Mean (SD) |
140.60 (2.51) |
0.20 (2.77) |
138.75 (4.57) |
-0.75 (2.87) |
142.50 (2.12) |
3.50 (4.95) |
140.27 (3.35) |
0.45 (3.24) |
| Median |
140.00 |
-1.00 |
138.00 |
-1.00 |
142.50 |
3.50 |
140.00 |
-1.00 |
| Min - Max |
139.00 - 145.00 |
-2.00 - 5.00 |
134.00 - 145.00 |
-4.00 - 3.00 |
141.00 - 144.00 |
0.00 - 7.00 |
134.00 - 145.00 |
-4.00 - 7.00 |