CMT02_PT Table 1 (Default) Concomitant Medications by Preferred Name

A concomitant medication table with the number of subjects and the total number of treatments by medication name sorted by frequencies.

cmt02_pt_1(
  adam_db,
  armvar = .study$planarm,
  prune_0 = TRUE,
  lbl_overall = .study$lbl_overall,
  deco = std_deco("CMT02_PT"),
  .study = list(planarm = "ARM", lbl_overall = NULL)
)

cmt02_pt_1_lyt(
  armvar = .study$planarm,
  lbl_overall = .study$lbl_overall,
  deco = std_deco("CMT02_PT"),
  .study = list(planarm = "ARM", lbl_overall = NULL)
)

cmt02_pt_1_pre(adam_db)

Arguments

adam_db: (dm) object containing the ADaM datasets
armvar: (character) variable used for column splitting
prune_0: (logical) remove 0 count rows
lbl_overall: (character) label used for overall column, if set to NULL the overall column is omitted
deco: (character) decoration with title, subtitles and main_footer content
.study: (list) with default values for the arguments of the function

Details

Data should be filtered for concomitant medication. (ATIREL == "CONCOMITANT").
Order by decreasing total number of patients with the specific medication.
Does not include a total column by default.

Functions

cmt02_pt_1_lyt: cmt02_pt_1 Layout
cmt02_pt_1_pre: cmt02_pt_1 Preprocessing

Examples

library(dm)

db <- syn_test_data() %>%
  dm_zoom_to("adcm") %>%
  filter(.data$ATIREL == "CONCOMITANT") %>%
  dm_update_zoomed() %>%
  cmt02_pt_1_pre()

cmt02_pt_1(adam_db = db)
#> Concomitant Medications by Preferred Name: {Specify Population}
#> Protocol: {{protocol}}
#> 
#> —————————————————————————————————————————————————————————————————————————————————————————————————
#> Other Treatment                                         A: Drug X    B: Placebo    C: Combination
#>                                                          (N=134)       (N=134)        (N=132)    
#> —————————————————————————————————————————————————————————————————————————————————————————————————
#> Total number of patients with at least one treatment   117 (87.3%)   116 (86.6%)    116 (87.9%)  
#> Total number of treatments                                 415           414            460      
#>   medname C_2/2                                        52 (38.8%)    58 (43.3%)      60 (45.5%)  
#>   medname B_1/4                                        52 (38.8%)    57 (42.5%)      59 (44.7%)  
#>   medname A_2/3                                        53 (39.6%)    50 (37.3%)      56 (42.4%)  
#>   medname C_1/2                                        51 (38.1%)    50 (37.3%)      56 (42.4%)  
#>   medname B_4/4                                        50 (37.3%)    45 (33.6%)      55 (41.7%)  
#>   medname A_3/3                                        45 (33.6%)    54 (40.3%)      48 (36.4%)  
#> —————————————————————————————————————————————————————————————————————————————————————————————————
#> 
#> Treatments are coded from the WHODrug Global B3 Format dictionary {version}. Multiple uses of a specific medication for a patient were counted once in the frequency for the medication. For frequency counts in "Total number of treatments", multiple uses of the same medication for a patient were counted separately. Standard footnote defining medications included in table (e.g., includes concomitant medications used at any time from first dose of study drug through 7 days after last dose of study drug).
cmt02_pt_1_lyt(
  armvar = "ACTARM",
  lbl_overall = NULL
)
#> A Pre-data Table Layout
#> 
#> Column-Split Structure:
#> ACTARM (lvls) 
#> 
#> Row-Split Structure:
#> CMDECOD (** analysis **) 
#> 
syn_test_data() %>%
  cmt02_pt_1_pre()
#> ── Metadata ────────────────────────────────────────────────────────────────────
#> Tables: `adsl`, `adae`, `adaette`, `adcm`, `addv`, … (15 total)
#> Columns: 846
#> Primary keys: 2
#> Foreign keys: 1